UK-recruiting trials from ClinicalTrials.gov — updated daily. Filter by therapeutic area.
The PulseSelect™ PFA Global Registry is a prospective, global, multi-center, observational post-approval study. Subjects will be treated with the PulseSelect™ PFA System and followed according to SOC.
Sponsor: Medtronic Cardiac Ablation Solutions
70 patients with heart failure, AF and CRT with BiV
Sponsor: Guy's and St Thomas' NHS Foundation Trust
The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients…
Sponsor: Icahn School of Medicine at Mount Sinai
LAAOS-4 aims to determine if catheter-based endovascular left atrial appendage occlusion prevents ischemic stroke or systemic embolism in participants with atrial fibrillation, who remain at high risk of stroke, despite…
Sponsor: Hamilton Health Sciences Corporation
Atrial fibrillation (AF) is one of the most common cardiac arrhythmias and cardioembolic stroke due to AF is its major complication. Direct oral anticoagulants (DOAC) reduce the risk of cardioembolism…
Sponsor: Insel Gruppe AG, University Hospital Bern
A randomized, placebo-controlled, participant-and investigator-blinded study to evaluate the efficacy in reducing atrial fibrillation burden as well as the safety, tolerability and pharmacokinetics of PKN605 in participants with atrial fibrillation
Sponsor: Novartis Pharmaceuticals
A study to evaluate the effect of abelacimab relative to placebo on the rate of ischemic stroke or systemic embolism (SE) in patients with Atrial Fibrillation (AF) who have been…
Sponsor: Anthos Therapeutics, Inc.
The study is designed to collect data on the acute and long-term (1 year) safety and effectiveness outcome when an ablation procedure is performed in a commercial and standard of…
Sponsor: Boston Scientific Corporation
Heart failure with preserved ejection fraction (HFpEF) causes symptoms of breathlessness and leg swelling. It is associated with significant number of hospital admissions and could lead to the patient's death.…
Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust
The purpose of this study is to learn about the safety and effects of the study medicine (PF-07328948) for the possible treatment of heart failure (HF).
Sponsor: Pfizer
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