Mental Health / Psychiatry
Psychiatry and mental health guidance, drug mechanism explainers and evidence updates across prescribing, safety and service-level clinical change.
Latest Guidelines
Obsessive-Compulsive Disorder and Body Dysmorphic Disorder (NICE CG31)
Diagnose OCD and BDD through systematic assessment of intrusive thoughts, images or impulses combined with repetitive behaviours or mental acts that cause significant distress or functional…
Self-Harm: Assessment, Management and Preventing Recurrence (NICE NG225)
Conduct comprehensive psychosocial assessment within 48 hours of all self-harm presentations (including low-lethality harm) to inform risk stratification and care planning, followed by follow-up within 1…
Eating Disorders: Recognition and Treatment (NICE NG69)
Use SCOFF questionnaire or validated screening tool in primary care to assess for weight loss, food restriction, compensatory behaviours and body image concerns when eating disorder…
Post-Traumatic Stress Disorder (NICE NG116)
Offer trauma-focused cognitive behavioural therapy (TF-CBT) or eye movement desensitisation and reprocessing (EMDR) as first-line psychological treatment, delivered by trained practitioners for 8–12 sessions in adults,…
ADHD: Diagnosis and Management (NICE NG87)
Refer suspected ADHD cases (presenting with inattention, hyperactivity, impulsivity, or functional impairment) to specialist services (paediatrician, psychiatrist, or specialist ADHD nurse) for diagnosis using comprehensive assessment…
Bipolar Disorder: Assessment and Management (NICE NG185)
Refer urgently to specialist psychiatry if bipolar disorder is suspected; diagnosis must be made by specialists using ICD-10 or DSM-5 criteria For acute mania give antipsychotics…
Trial Radar
ALTO-100 in Bipolar Disorder With Depression (BD-D)
ALTO-100 tested against placebo for treating depression in bipolar disorder patients already on mood stabilizers or antipsychotics.
NATesting the Efficacy of 100mg Vitamin-B6 Daily for Sensory Reactivity in Autism
High-dose vitamin B6 showed no significant benefit for reducing anxiety or sensory sensitivity in autistic adults compared to…
TrialAddressing Pregnant Women’s First Trimester Worries and Information Needs With mHealth Solutions
What is being tested: An mHealth (mobile health) solution designed to address pregnant women's anxieties and information needs…
PHASE3Relapse Prevention Trial Evaluating KarXT Treatment in Schizophrenia
KarXT may help prevent relapse in schizophrenia patients already responding to treatment.
Clinical News
Born in jail to a mum with a heroin addiction – how US teenager Abby has been affected by drugs
Prenatal opioid exposure consequences: Children born to mothers with opioid addiction face significant long-term developmental and health impacts,…
16 Oct 2026Charity ‘terrified’ closure could leave mums suicidal
Key Takeaways for Clinical Practice Potential closure of the Happy Mums Foundation threatens specialist support services for women…
15 Oct 2026Antidepressants: new safety measures for all patients to improve communication of the risk of suicidal thoughts and behaviours and persistent sexual dysfunction
All antidepressants now require enhanced safety communication about risks of suicidal ideation/behaviour and persistent sexual dysfunction to ensure…
12 Oct 2026New mental health directory launches
A new mental health directory has been launched to signpost healthcare professionals and patients to available mental health…
Relevant Mechanisms
Dopamine D2 Receptor
Dopamine D2 Receptor is a clinically relevant Drug Science explainer. Dopamine (DA) is a monoamine neurotransmitter with distinct functional roles…
MechanismSerotonin/Noradrenaline Reuptake
Serotonin/Noradrenaline Reuptake is a clinically relevant Drug Science explainer. Serotonin (5-hydroxytryptamine, 5-HT) and noradrenaline (norepinephrine, NA) are monoamine neurotransmitters with…
CPD, Podcasts & Webinars
Mental Health in Primary Care — NICE Depression Guidelines Update
Apply NICE NG222 depression guidance using a person-centred choice of psychological, behavioural and pharmacological interventions. Review SSRI initiation,…
cpd moduleMHRA Drug Safety: Valproate in Women of Childbearing Potential
Explain the fetal and developmental risks associated with valproate exposure in pregnancy. Apply MHRA Pregnancy Prevention Programme requirements,…
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