Trial Collections

Themed entry points into Trial Radar

These collections group high-interest trial areas with nearby guidelines, Drug Science explainers and clinical briefs, so you can move from headline results to practical context without hopping across archives.

6 curated themes 1,963 total trials indexed Trial Radar plus linked clinical context

Collections

Use these to orient quickly in a topic area, then continue into the full trial archive or the relevant specialty hub.

Cardio-Renal

Cardiovascular, kidney and metabolic outcomes

A practical route into outcomes trials spanning heart failure, chronic kidney disease and diabetes-driven cardiovascular risk.

Recruiting NCT06230861

Effects of Quercetin on Cardiometabolic Outcomes

Quercetin supplement compared to placebo in randomized trial to test whether it improves heart disease and diabetes risk factors.

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Recruiting NCT07436299

Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation

Heart failure and atrial fibrillation are two of the most common heart diseases globally. Nearly half of all patients with heart failure…

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Phase III Recruiting NCT07776509

A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus

The study will evaluate how well AZD6234 works and how safe it is in adults with excess weight or obesity. Efficacy of…

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Drug Science HMG-CoA Reductase — Statins

Clinical Brief Campaigners hold vigil as stroke unit closes

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Respiratory

Airways, biologics and exacerbation prevention

Trials shaping asthma, COPD and severe airways disease management, from biologics to exacerbation reduction strategies.

Phase IV Recruiting NCT07761351

A Randomized Controlled Trial Comparing Percutaneous CT-Guided Biopsy and Shape-Sensing Robotic-Assisted Bronchoscopy

What is being tested: The ENCOMPASS study compares diagnostic accuracy and safety outcomes between CT-guided percutaneous lung biopsy and shape-sensing robotic-assisted bronchoscopy…

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Phase II Recruiting NCT05947955

Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)

BTI-203 is a randomized, double-blind, placebo-controlled, multicenter, Phase 2 proof-of-concept (POC) study to evaluate the efficacy and safety of rhu-pGSN plus standard…

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Recruiting NCT06282718

A Long-term Observational Study Evaluating the Presentation and Management of Acute Respiratory Tract Infections in Primary Care Across Europe

Long-term European study examining how respiratory infections present and are managed in GP surgeries.

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Drug Science CFTR Modulation

Clinical Brief Only around half of primary school children got their flu vaccine last year

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Immunology

Inflammation, biologics and immune pathways

Immune-mediated disease research across rheumatology, dermatology and inflammatory pathways with clinically useful mechanism context.

Phase II Active Not Recruiting NCT06029972

Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis

A new drug called tilpisertib fosmecarbil tested against placebo in patients with moderate-to-severe ulcerative colitis to see if it improves symptoms by…

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Active Not Recruiting NCT06585267

Development of a New Patient Reported Outcome Measure (PROM) to Assess Patient’s Emotional Wellbeing, and Perceptions of Total Knee Replacement Surgery for the Treatment of Knee Arthritis

Researchers created a new questionnaire to measure how knee replacement patients feel emotionally and perceive their surgery outcomes.

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Phase II Active Not Recruiting NCT05242484

A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis

Combining two biologic drugs (guselkumab and golimumab) tested for treating ulcerative colitis in patients who haven't responded to other treatments.

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Drug Science S1P Receptor Modulation — MS/IBD

Clinical Brief Mum’s perforated bowel ordeal after scan error

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Oncology

Checkpoint, targeted and precision oncology trials

A fast entry point into oncology trial activity, combining registry-linked studies with the supporting drug science and related clinical briefings.

Phase III Recruiting NCT07431281

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

The purpose of this study is to evaluate the efficacy and safety of sonesitatug vedotin in combination with capecitabine with or without…

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Phase I Recruiting NCT07335497

CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

The purpose of this study is to determine the safety and tolerability of monotherapy CR-001 and identify the maximum tolerated dose (MTD),…

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Phase III Recruiting NCT07549412

A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)

This study aims to address the unmet medical need of participants with metastatic colorectal cancer (mCRC) who have previously been treated with…

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Drug Science BRAF/MEK Pathway — Melanoma

Clinical Brief ‘My cancer spread while I waited months for surgery’: The cost of England’s cancer wait times

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Neuro / Mental Health

Neurology and mental health evidence watch

Trials and linked clinical context for neurology and psychiatry where practice is moving quickly and clinicians need concise orientation.

Phase I Recruiting NCT06565195

A Clinical Trial of LY3962681 in Healthy Volunteers and in Patients With Parkinson’s Disease

Drug being tested: LY3962681, a novel investigational compound undergoing evaluation for safety, tolerability, and pharmacokinetic/pharmacodynamic properties in both healthy volunteers and Parkinson's…

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Recruiting NCT07227896

Real-World Study of Foslevodopa/Foscarbidopa to Assess Quality of Life Outcomes in Adult Participants Earlier Within Advanced Parkinson Disease

What is being tested: Foslevodopa/foscarbidopa (a continuous subcutaneous infusion therapy) is being evaluated for its effects on quality of life outcomes in…

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Phase III Active Not Recruiting NCT04437511

A Study of Donanemab (LY3002813) in Participants With Early Alzheimer’s Disease (TRAILBLAZER-ALZ 2)

Donanemab slows cognitive decline in early Alzheimer's disease; follow-up study monitors long-term safety and effectiveness.

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Related Guideline Atogepant for treating migraine

Drug Science S1P Receptor Modulation — MS/IBD

Clinical Brief ‘Game-changing’ suicide prevention charity expands

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Infectious Disease

Infection, antimicrobial and outbreak-linked research

Current infectious disease trials with the nearby clinical updates and guidance needed to place them in real-world practice.

Phase II Active Not Recruiting NCT06497504

Study of Bepirovirsen in Participants Living With Human Immunodeficiency Virus and Chronic Hepatitis B Virus Infection (B-Focus)

Bepirovirsen compared to placebo for treating people with both HIV and hepatitis B infection, measuring effectiveness and safety.

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Phase II Active Not Recruiting NCT05461170

SOLSTICE: Combination Therapy for the Treatment of Chronic Hepatitis D Infection.

Two new drugs tested together in hepatitis D patients to check if they're safe and effective.

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Phase III Recruiting NCT07650916

A Study to Investigate Cabotegravir Ultra Long-Acting (CAB ULA) Plus Rilpivirine Ultra Long-Acting (RPV ULA) in Adults and Adolescents With HIV Who Are Virologically Suppressed

What is being tested: Cabotegravir ultra long-acting (CAB ULA) plus rilpivirine ultra-acting (RPV ULA) injections are being compared against standard long-acting formulations…

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Drug Science IL-6 Signalling

Clinical Brief Running costs of vaccine damage scheme more than double amount paid to victims

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