Neurology
Neurology guidelines, trial updates, mechanisms and education across headache, neuroinflammation, movement disorders and specialist prescribing.
Latest Guidelines
Software with artificial intelligence (AI)-derived algorithms to help interpret electroencephalograms (EEGs) for suspected epilepsy: early-use assessment
AI-assisted EEG interpretation software can support clinicians in identifying abnormalities suggestive of epilepsy, but should complement rather than replace expert clinical review—use as a triage or…
Mirdametinib for treating symptomatic and inoperable plexiform neurofibromas associated with neurofibromatosis type 1 in people 2 to 17 years
Mirdametinib is indicated for symptomatic and inoperable plexiform neurofibromas in children aged 2-17 years with neurofibromatosis type 1 (NF1); confirm diagnosis and operability status before initiating…
Atogepant for treating migraine
Atogepant is recommended as a preventive treatment option for episodic migraine in adults; consider initiating in patients with ≥4 migraine days per month who have failed…
Oxybutynin hydrochloride for managing neurogenic detrusor overactivity in people 6 years and over with spinal cord injury or spina bifida (terminated appraisal)
Oxybutynin is effective for neurogenic detrusor overactivity in patients aged 6+ years with spinal cord injury or spina bifida—consider as first-line antimuscarinic therapy for managing symptoms…
2022 EAN/EFNS Guidelines on Dementia Diagnosis and Management
This EAN guideline addresses 2022 EAN/EFNS Guidelines on Dementia Diagnosis and Management in Neurology. Use it to review current recommendation wording, eligibility criteria, and implementation considerations…
2023 EAN Guidelines on the Management of Multiple Sclerosis
This EAN guideline addresses 2023 EAN Guidelines on the Management of Multiple Sclerosis in Neurology. Use it to review current recommendation wording, eligibility criteria, and implementation…
Trial Radar
Ginger-PD: Ginger as a Modifier of Ghrelin Levels and Gut Function in Parkinson’s Disease
This study will test whether taking ginger supplements can increase ghrelin, a hunger hormone that is decreased in…
TrialWearable for Assessing Tremor and Continuous Health in Parkinson’s Disease and Essential Tremor
What is being tested: Non-invasive wearable sensors are being evaluated to measure tremor and upper-limb movement patterns in…
TrialDeveloping a New EEG Method for the Early Diagnosis of Dementia
Researchers are testing whether routine EEG scans with new analysis software can detect dementia earlier than current methods.
PHASE3Study to Evaluate the Efficacy, Safety and Tolerability of IMU-838 in Patients With Relapsing Multiple Sclerosis
IMU-838 reduced relapses in relapsing multiple sclerosis compared to placebo in this large randomised trial.
Clinical News
Nobel Prize awarded for revealing inner workings of the brain
Karl Deisseroth, Peter Hegemann, and Georg Nagel have been awarded the Nobel Prize for developing optogenetics, a technique…
22 Sep 2026Sisters with life-limiting condition taking NHS fight to Parliament
Two sisters with life-limiting neurological condition are escalating NHS access dispute to parliamentary level, highlighting potential gaps in…
20 Sep 2026Smart beds and motion sensors – is this the future of dementia care?
Key takeaways for clinical practice: Smart home technology including motion sensors, bed monitors, and wearable devices (socks) can…
10 Sep 2026Migraines and acne among five more conditions pharmacists can treat
Pharmacists in England will expand their scope to treat migraines and acne alongside existing common conditions, bringing the…
Relevant Mechanisms
CGRP Pathway — Migraine
CGRP Pathway — Migraine is a clinically relevant Drug Science explainer. Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide…
MechanismDopamine D2 Receptor
Dopamine D2 Receptor is a clinically relevant Drug Science explainer. Dopamine (DA) is a monoamine neurotransmitter with distinct functional roles…
MechanismS1P Receptor Modulation — MS/IBD
S1P Receptor Modulation — MS/IBD is a clinically relevant Drug Science explainer. Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite generated…
MechanismSerotonin/Noradrenaline Reuptake
Serotonin/Noradrenaline Reuptake is a clinically relevant Drug Science explainer. Serotonin (5-hydroxytryptamine, 5-HT) and noradrenaline (norepinephrine, NA) are monoamine neurotransmitters with…
CPD, Podcasts & Webinars
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