Dermatology
Dermatology guidance, immune pathway mechanisms and clinical updates across inflammatory skin disease, biologics and targeted therapy.
Latest Guidelines
Subcutaneous spesolimab 1-ml formulation for preventing generalised pustular psoriasis flares in people 12 years and over (terminated appraisal)
This NICE publication is marked as a terminated appraisal, so it functions as a status notice rather than an active treatment recommendation for routine care. If…
Hidradenitis Suppurativa: Assessment and Management (NICE NG73)
Diagnose hidradenitis suppurativa clinically based on recurrent painful nodules, abscesses, sinus tracts, and scars localised to intertriginous areas (axillae, groin, inframammary folds), then assess severity using…
Non-Melanoma Skin Cancer: Diagnosis and Management (NICE NG12)
Refer suspected BCC or SCC to specialist dermatology using 2-week wait pathway if diagnosis is clear; use urgent referral for lesions >4 mm depth, poorly demarcated,…
Acne Vulgaris: Management (NICE NG198)
Prescribe topical benzoyl peroxide monotherapy for mild facial acne; for mild-to-moderate acne, combine benzoyl peroxide with a topical retinoid or topical antibiotic Prescribe oral antibiotics (doxycycline…
Atopic Eczema in Under 12s: Diagnosis and Management (NICE NG190)
Diagnose atopic eczema clinically based on itching, typical morphology and distribution, onset before age 2 years, and history of dry skin or atopic disease; no diagnostic…
Psoriasis: Assessment and Management (NICE NG10)
Assess psoriasis severity using BSA, PASI, or clinical judgement; classify as mild (
Trial Radar
Long-Term Safety and Efficacy Evaluation of Amlitelimab in Participants of Previous Amlitelimab Moderate to Severe Atopic Dermatitis Clinical Trials
Long-term safety and efficacy study of amlitelimab for moderate-to-severe atopic dermatitis, including drug withdrawal to assess treatment durability.
PHASE1A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK)
Study comparing how the body processes nusinersen delivered via an implantable device versus lumbar puncture in spinal muscular…
PHASE2Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis
Multi-drug trial testing new treatments for moderate to severe eczema in adults.
PHASE3A Research Study on How Well Concizumab Works for You if You Have Haemophilia A or B With or Without Inhibitors
Concizumab daily injections tested in haemophilia A/B patients to prevent bleeds over 2-4 years.
Clinical News
Hundreds contact BBC about mystery skin condition ‘hell’ – but doctors can’t agree it exists
Doctors remain divided on whether a severe skin condition reported by hundreds of patients represents extreme eczema or…
29 Mar 2026Our skin is falling off and no-one can tell us why
Topical Steroid Withdrawal: Key Clinical Takeaways TSW is now subject to formal UK research: Growing social media documentation…
24 Feb 2026Tens of thousands with vitiligo to be offered “life-changing” new cream on NHS to restore skin colour
Tens of thousands of people living with vitiligo affecting their face are to be offered the first approved…
27 Oct 2025Isotretinoin – updates to prescribing guidance and survey of services
The Commission on Human Medicines (CHM) has endorsed changes to isotretinoin prescribing guidance. In addition, CHM is seeking…
Relevant Mechanisms
BRAF/MEK Pathway — Melanoma
BRAF/MEK Pathway — Melanoma is a clinically relevant Drug Science explainer. The MAPK signalling cascade (RAS-RAF-MEK-ERK) transmits extracellular growth signals…
MechanismIL-4/IL-13 Axis
IL-4/IL-13 Axis is a clinically relevant Drug Science explainer. Interleukin-4 (IL-4) and interleukin-13 (IL-13) are hallmark type 2 cytokines produced…
MechanismJAK-STAT Pathway
JAK-STAT Pathway is a clinically relevant Drug Science explainer. The Janus kinase–signal transducer and activator of transcription (JAK-STAT) pathway is…
MechanismThe IL-17/IL-23 Axis
The IL-17/IL-23 Axis is a clinically relevant Drug Science explainer. The IL-23/IL-17 axis is a central driver of immune-mediated inflammatory…
MechanismTNF-α Signalling
TNF-α Signalling is a clinically relevant Drug Science explainer. Tumour necrosis factor-alpha (TNF-α) is a pleiotropic pro-inflammatory cytokine produced predominantly…
CPD, Podcasts & Webinars
No specialty-tagged education live yet
Dermatology podcasts, webinars and CPD modules will appear here as new education is published and tagged.
Useful starting points in Dermatology
Long-Term Safety and Efficacy Evaluation of Amlitelimab in Participants of Previous Amlitelimab Moderate to Severe Atopic Dermatitis Clinical Trials
Long-term safety and efficacy study of amlitelimab for moderate-to-severe atopic dermatitis, including drug withdrawal to assess treatment durability.
TrialA Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK)
Study comparing how the body processes nusinersen delivered via an implantable device versus lumbar puncture in spinal muscular…
TrialPlatform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis
Multi-drug trial testing new treatments for moderate to severe eczema in adults.
Education that still supports this area
JAK Inhibitors: Updated Safety Signals, Patient Selection and Post-ORAL Surveillance
Recorded webinar focused on JAK inhibitors in rheumatology and immune-mediated inflammatory disease. Reviews JAK-STAT signalling, patient selection, ORAL…
PodcastJAK Inhibitors: Updated Safety Signals, Patient Selection and Post-ORAL Surveillance
JAK inhibitors target the JAK-STAT pathway, interrupting intracellular cytokine signalling across several inflammatory diseases. ORAL Surveillance reshaped risk…
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