Drug safety updates, recalls and regulatory warnings from MHRA, organised for rapid clinical review and specialty follow-up.
Parenteral nutrition must be administered through appropriate filters across all care settings to prevent particulate matter embolism, which can be fatal Non-filtered PN administration represents a significant patient safety risk and has been linked…
02 Sep 2026 · Read clinical summaryParenteral nutrition must be administered through appropriate filters across all care settings to prevent particulate matter embolism, which can be fatal Non-filtered PN administration represents a significant patient…
Domperidone is now contraindicated in confirmed or suspected phaeochromocytoma due to risk of severe hypertensive episodes from catecholamine release All domperidone product information has been updated to reflect…
Botulinum toxin type A: Key clinical takeaways Iatrogenic botulism risk: Botulinum toxin type A can spread beyond injection sites, causing systemic botulism with serious consequences; clinicians must recognise…
Angioedema associated with ACE-inhibitors can present with delayed onset, requiring heightened clinical awareness and vigilance beyond initial prescription periods Bradykinin-mediated angioedema (ACE-inhibitor induced) requires different management from histamine-mediated…
Amiodarone carries serious risks of pulmonary, hepatic, and thyroid toxicity requiring regular patient monitoring and supervision throughout treatment Healthcare professionals must ensure appropriate baseline investigations and regular follow-up…
Amiodarone carries serious risks of pulmonary, hepatic, and thyroid toxicity requiring baseline assessment and regular monitoring throughout treatment Patients on amiodarone require structured supervision with scheduled reviews to…
The MHRA has identified suicidal thoughts and behaviours as a safety concern with finasteride and dutasteride, requiring additional risk minimisation measures in clinical practice. Psychiatric adverse effects and…
Nasal decongestant sprays/drops containing xylometazoline or oxymetazoline carry a risk of rebound congestion and rhinitis medicamentosa with overuse, requiring cautious patient counselling on duration of use. Tachyphylaxis (reduced…
A falsified version of Mounjaro (tirzepatide) KwikPen 15mg solution for injection has been found supplied through one online pharmacy in the UK. The falsified product is labelled with…
The Commission on Human Medicines (CHM) has temporarily restricted use of the IXCHIQ Chikungunya vaccine in people aged 65 years and over following very rare fatal reactions reported…
IXCHIQ Chikungunya vaccine: updates to restrictions of use following safety revi...
Semaglutide (Wegovy, Ozempic and Rybelsus): risk of Non-arteritic Anterior Ische...