Cardiology / Cardiovascular
Cardiovascular guidance, trial updates, drug mechanisms and CPD resources for clinicians following rapidly changing prevention, heart failure and cardiometabolic evidence.
Latest Guidelines
Semaglutide for reducing the risk of major adverse cardiovascular events in people with cardiovascular disease and overweight or obesity
Semaglutide is recommended for adults with established cardiovascular disease and overweight/obesity to reduce major adverse cardiovascular events – consider prescribing as part of a comprehensive cardiovascular…
EMA Guideline on Clinical Investigation of Medicinal Products for Heart Failure
This EMA guideline addresses EMA Guideline on Clinical Investigation of Medicinal Products for Heart Failure in Cardiology / Cardiovascular. Use it to review current recommendation wording,…
2021 ESC Guidelines on Cardiac Pacing and Cardiac Resynchronisation Therapy
Covers indications for cardiac pacing and cardiac resynchronization therapy (CRT) • Provides guidance on device selection, implantation techniques, and optimization • Addresses follow-up protocols, remote monitoring,…
2024 ESC Guidelines for the Management of Atrial Fibrillation
Covers AF classification, stroke risk assessment (CHA2DS2-VASc), and bleeding risk (HAS-BLED) • Provides recommendations for rate vs rhythm control strategies • Addresses anticoagulation choices including DOACs…
2022 ESC Guidelines for the Management of Patients with Ventricular Arrhythmias
Covers risk stratification for sudden cardiac death and indications for ICD implantation • Provides management recommendations for ventricular tachycardia and ventricular fibrillation • Addresses antiarrhythmic drug…
2023 ESC Guidelines on the Management of Endocarditis
Covers diagnostic criteria for infective endocarditis (Duke criteria) and appropriate imaging modalities • Provides antimicrobial treatment recommendations based on causative organisms and valve involvement • Addresses…
Trial Radar
Exercise Intervention as an Adjunct to Medical Therapy in Newly Diagnosed Patients With Pulmonary Arterial Hypertension
Intervention being tested: A structured exercise programme initiated early after pulmonary arterial hypertension (PAH) diagnosis, delivered alongside standard…
PHASE3A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
What is being tested: The efficacy of triple therapy (budesonide/glycopyrronium/formoterol – BGF MDI) versus dual therapy (glycopyrronium/formoterol –…
TrialChronic Limb-Threatening Ischemia Treated With Intravascular Lithotripsy Observational Study
Intervention being tested: Real-world effectiveness and safety of intravascular lithotripsy (IVL) using the Shockwave system to treat calcified…
TrialOptical Coherence Tomography And NEphropathy: The OCTANE Study
What is being tested: Optical coherence tomography (OCT) imaging to detect structural and functional changes in blood vessels…
Clinical News
The struggle to get hold of medication in England is set to get worse
Drug supply shortages are affecting multiple therapeutic areas – patients with cardiovascular disease, stroke prevention, ophthalmology, and psychiatric…
30 Apr 2026How can a heart rate tracker help you?
I'm unable to provide a summary as the article content hasn't been included—only the title and a brief…
21 Apr 2026Bird flu vaccine trial against potential pandemic strain begins
H5N1 vaccine trial has commenced targeting a potential pandemic strain currently circulating in bird populations without documented human-to-human…
14 Apr 2026Women’s voices to be at the heart of renewed health strategy
Women's Health Strategy will be renewed with enhanced mechanisms to centre female patient voices in healthcare planning and…
Relevant Mechanisms
Coagulation Factor Xa/IIa — DOACs
Coagulation Factor Xa/IIa — DOACs is a clinically relevant Drug Science explainer. The coagulation cascade proceeds via two convergent pathways…
MechanismGLP-1 Receptor Agonism
GLP-1 Receptor Agonism is a clinically relevant Drug Science explainer. Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from intestinal…
MechanismHMG-CoA Reductase — Statins
HMG-CoA Reductase — Statins is a clinically relevant Drug Science explainer. 3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase catalyses the rate-limiting step…
MechanismPCSK9 Inhibition
PCSK9 Inhibition is a clinically relevant Drug Science explainer. PCSK9 (proprotein convertase subtilisin/kexin type 9) is a serine protease secreted…
MechanismRAAS Pathway
RAAS Pathway is a clinically relevant Drug Science explainer. The renin-angiotensin-aldosterone system (RAAS) is a hormonal cascade governing blood pressure,…
CPD, Podcasts & Webinars
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