Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Rheumatology Women's Health Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

1963 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

1963 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

active not recruiting Phase II Gastroenterology
Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis
A new drug called tilpisertib fosmecarbil tested against placebo in patients with moderate-to-severe ulcerative colitis to see if it improves symptoms by week 12.
11 Sep 2026 NCT06029972
● Recruiting Phase I Gastroenterology
Human Mass Balance Study of [14C] Ontunisertib in Healthy Volunteers
Study tracking how the body absorbs, processes and eliminates a single dose of ontunisertib using radioactive labelling in healthy men.
11 Sep 2026 NCT07672574
active not recruiting Phase II
A Study of Ianalumab (VAY736) in Patients With Primary Immune Thrombocytopenia (ITP) Previously Treated With at Least Two Lines of Therapies
Ianalumab is tested in adults with hard-to-treat immune thrombocytopenia who've failed previous treatments.
11 Sep 2026 NCT05885555
● Recruiting Oncology
International Prospective REgistry on Pre-pectorAl Breast REconstruction
This is an international multicenter prospective cohort study aimed at collecting data on breast reconstruction techniques with pre-pectoral implants after mastectomy for breast cancer.…
11 Sep 2026 NCT05817175
● Recruiting Phase II Gastroenterology
A Novel COMBinATorial Therapy With Albumin and Enoxaparin in Patients With Decompensated Cirrhosis at High-risk of Poor Outcome (COMBAT Trial).
The goal of this clinical trial is to determine primarily whether a combinatorial therapy based on the administration of human albumin and enoxaparin is…
11 Sep 2026 NCT05895136
● Recruiting Cardiology / Cardiovascular
Mechanisms of Atrial Pathoelectrophysiology in HCM
This study aims to learn why atrial fibrillation (AF), a type of irregular heartbeat, happens more often and is harder to treat in people…
11 Sep 2026 NCT07454135
● Recruiting Cardiology / Cardiovascular
The Origin and Role of Thromboembolism in the Pathogenesis of Ischaemic Stroke
Ischaemic stroke is usually due to occlusion of a cerebral artery by thrombus. However, it is often difficult to identify the source of thrombus,…
11 Sep 2026 NCT05636748
● Recruiting Oncology
Breath Research Narrow Validation for Gastrointestinal Cancer Detection
The investigators of this study are developing a simple breath test to help detect gastrointestinal (gut) cancers earlier, including cancers of the oesophagus (food…
11 Sep 2026 NCT07714538
● Recruiting Neurology
Natural History of Type 1 Interferonopathies: Insights From a European Cohort
European study tracking type 1 interferonopathy progression in children and adults to improve diagnosis, prognosis, and personalise treatment options.
10 Sep 2026 NCT07040774
● Recruiting Diabetes / Metabolic
Effects of Quercetin on Cardiometabolic Outcomes
Quercetin supplement compared to placebo in randomized trial to test whether it improves heart disease and diabetes risk factors.
10 Sep 2026 NCT06230861
active not recruiting Cardiology / Cardiovascular
Early Valve Replacement Guided by Biomarkers of LV Decompensation in Asymptomatic Patients With Severe AS
Early aortic valve surgery guided by heart scarring markers may improve outcomes in asymptomatic patients with severe stenosis.
10 Sep 2026 NCT03094143
active not recruiting Infectious Disease
Accelerometry and Rehabilitation After Knee Replacement Study (ARK)
Wearable sensors with remote monitoring may improve exercise compliance and outcomes after knee replacement compared to standard physiotherapy.
10 Sep 2026 NCT05412940
● Recruiting Phase II
Imeroprubart in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
A study testing whether a new drug called Imeroprubart helps adults with chronic nerve inflammation and weakness.
10 Sep 2026 NCT07032662
active not recruiting
Versius Paediatrics Study
Testing whether Versius robotic surgery is safe and effective for urological procedures in children, starting with three procedures then expanding if safe.
10 Sep 2026 NCT06539442
active not recruiting
Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)
Older adults with leaky mitral valves randomly received either catheter-based or surgical repair to compare which approach works better.
10 Sep 2026 NCT05051033
● Recruiting Phase III Respiratory / COPD / Asthma
A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer’s Disease
This study will evaluate the efficacy and safety of trontinemab in participants with biomarker evidence of Alzheimer's Disease (AD) pathology but with no cognitive…
10 Sep 2026 NCT07717411
● Recruiting Neurology
Digital App for Speech & Health Monitoring
Many people living with neurodegenerative conditions like dementia, motor neuron disease (MND), multiple sclerosis (MS), and Parkinson's disease (PD), suffer from speech problems. Using…
10 Sep 2026 NCT06450418
● Recruiting Phase II Respiratory / COPD / Asthma
Trial Comparing the Safety and Efficacy of Two Different Oral VPV Doses With Placebo as Treatment for RV in Participants With COPD
Compare the safety and efficacy of two different oral vapendavir doses with placebo in order to determine the appropriate dose of vapendavir to reduce…
10 Sep 2026 NCT07610395
● Recruiting Respiratory / COPD / Asthma
Perpetual Observational Study – Ventilator Associated Pneumonia
Ventilator-Associated Pneumonia (VAP) is a bacterial respiratory infection that patients in the Intensive Care Unit (ICU) often get when they cannot breathe for themselves…
10 Sep 2026 NCT05719259
● Recruiting Phase II Respiratory / COPD / Asthma
Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)
BTI-203 is a randomized, double-blind, placebo-controlled, multicenter, Phase 2 proof-of-concept (POC) study to evaluate the efficacy and safety of rhu-pGSN plus standard of care…
10 Sep 2026 NCT05947955
● Recruiting Phase II Respiratory / COPD / Asthma
A Study to Investigate the Efficacy and Safety of SC0032, a Magnesium Salt Oral Spray, in Adults With Refractory or Unexplained Chronic Cough
This is a randomized placebo-controlled, parallel-arm study to determine the safety and efficacy of SC0032 in participants with RCC
10 Sep 2026 NCT07690059
● Recruiting Phase III Diabetes / Metabolic
A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
The study will evaluate how well AZD6234 works and how safe it is in adults with excess weight or obesity. Efficacy of AZD6234 will…
10 Sep 2026 NCT07776509
● Recruiting Cardiology / Cardiovascular
Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation
Heart failure and atrial fibrillation are two of the most common heart diseases globally. Nearly half of all patients with heart failure also have…
10 Sep 2026 NCT07436299
● Recruiting Phase III Cardiology / Cardiovascular
Efficacy and Safety of Intranasal Cenegermin in Adult Participants With Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)
This is a phase 3, randomized, multicenter, vehicle-controlled, double-masked study to evaluate the efficacy and safety of intranasal cenegermin compared with vehicle control in…
10 Sep 2026 NCT07453888
● Recruiting Phase I Oncology
CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors
The purpose of this study is to determine the safety and tolerability of monotherapy CR-001 and identify the maximum tolerated dose (MTD), and/or optimal…
10 Sep 2026 NCT07335497
active not recruiting Phase III Diabetes / Metabolic
A Research Study on How Well Semaglutide Helps Children and Teenagers With Excess Body Weight Lose Weight
Semaglutide weekly injections help children and teenagers lose weight better than placebo, alongside lifestyle support.
09 Sep 2026 NCT05726227
● Recruiting
Influence of Gut Microbiome in Gallstone Disease
Study examining whether gut bacteria composition relates to gallstone complications and changes after gallbladder removal surgery.
09 Sep 2026 NCT05732480
active not recruiting Rheumatology
Development of a New Patient Reported Outcome Measure (PROM) to Assess Patient’s Emotional Wellbeing, and Perceptions of Total Knee Replacement Surgery for the Treatment of Knee Arthritis
Researchers created a new questionnaire to measure how knee replacement patients feel emotionally and perceive their surgery outcomes.
09 Sep 2026 NCT06585267
● Recruiting Respiratory / COPD / Asthma
A Long-term Observational Study Evaluating the Presentation and Management of Acute Respiratory Tract Infections in Primary Care Across Europe
Long-term European study examining how respiratory infections present and are managed in GP surgeries.
09 Sep 2026 NCT06282718
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
This is a Phase III, randomized, double-blind, parallel-group, placebo-controlled, multicenter study to investigate CV outcomes with elecoglipron compared with placebo, in adults with heart…
09 Sep 2026 NCT07761117
● Recruiting Oncology
Chemo Brain Prehab Project
Colorectal cancer is 37% higher in the North West than the national average and is treated by chemotherapy, including fluorouracil, capecitabine, and oxaliplatin. A…
09 Sep 2026 NCT07341217
● Recruiting Phase III Diabetes / Metabolic
A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
This is a Phase III, randomized, double-blind, parallel-group, placebo-controlled multicenter study to investigate outcomes with elecoglipron compared with placebo in participants with CKD with…
09 Sep 2026 NCT07753993
● Recruiting Phase III Respiratory / COPD / Asthma
A Study to Investigate the Long-term Safety and Efficacy of Belimumab in Adults With Interstitial Lung Disease (ILD) Associated With Systemic Sclerosis (SSc) and Other Connective Tissue Diseases (CTD) (BLISSconneCTD-OLE)
This is an open label extension (OLE) study of an ongoing randomized controlled parent clinical studies 218224 (NCT05878717) and 221672 (NCT06572384) which aim to…
09 Sep 2026 NCT06716606
● Recruiting Cardiology / Cardiovascular
Establishing the Incidence of Tako-tsubo Cardiomyopathy in Scotland
Acute stress-induced (Takotsubo cardiomyopathy) presents like a heart attack and is triggered by intense emotional or physical stress. Although coronary arteries are unobstructed, it…
09 Sep 2026 NCT03299569
● Recruiting Phase III Cardiology / Cardiovascular
Single-arm Study of IgPro20 in Adults With Secondary Immune Deficiencies Due to Hematologic Malignancies Treated With B-cell Targeting Chimeric Antigen Receptor T-cell and T-cell Redirecting Therapies
This is a prospective, multicenter, open-label, single-arm study to assess the efficacy, safety, and pharmacokinetics (PK) of IgPro20 in adults with hematologic malignancies treated…
09 Sep 2026 NCT07648264
● Recruiting Cardiology / Cardiovascular
Barts Sex-CAD Database – Sex Hormones and Inflammatory Status in Coronary Artery Disease
There is a lack of understanding of how Coronary Artery Disease (CAD) - meaning the blocking or furring up of the arteries of the…
09 Sep 2026 NCT06327984
● Recruiting Oncology
Observational Study of Acalabrutinib in Patients With Chronic Lymphocytic Leukaemia in the United Kingdom
This is a retrospective observational research study to describe the characteristics and real-world clinical outcomes of patients with chronic lymphocytic leukaemia receiving acalabrutinib in…
09 Sep 2026 NCT05557695
● Recruiting Phase III Oncology
A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)
This study aims to address the unmet medical need of participants with metastatic colorectal cancer (mCRC) who have previously been treated with irinotecan, oxaliplatin,…
09 Sep 2026 NCT07549412
● Recruiting Oncology
PRostate Cancer Enhanced Diagnosis by Calibration Technology
The CARE® Phantom system is a medical device system that is being developed has been designed to enable the quantitative measurement of the apparent…
09 Sep 2026 NCT06607783
● Recruiting Oncology
Anatomical Landmarks for Chest Wall Perforators Used for Partial Breast Reconstruction
The aim of this 6-month proof-of-concept study is to map out the chest wall perforators in relation to anatomical landmarks for partial breast reconstruction.
09 Sep 2026 NCT07006662
● Recruiting Phase III Oncology
Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2
The purpose of this study is to evaluate the efficacy and safety of sonesitatug vedotin in combination with capecitabine with or without rilvegostomig in…
09 Sep 2026 NCT07431281
active not recruiting
BONAPH1DE, A Prospective Observational Study of Patients With Primary Hyperoxaluria Type 1 (PH1)
Study tracking disease progression and lumasiran treatment outcomes in primary hyperoxaluria type 1 patients over time.
08 Sep 2026 NCT04982393
active not recruiting Phase I Diabetes / Metabolic
To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
Phase I trial testing inavolisib alone and combined with standard breast cancer treatments in patients with PIK3CA-mutant tumours.
08 Sep 2026 NCT03006172
● Recruiting Phase II Dermatology
A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C)
Brenipatide injections tested against placebo in patients with constipation-type irritable bowel syndrome over 35 weeks for safety and effectiveness.
08 Sep 2026 NCT07545772
● Recruiting Oncology
EORTC Metastatic Breast Cancer Module Development
The overall aim of this project is to help improve the Health Related Quality of Life (HRQOL) of metastatic breast cancer (MBC) patients. There…
08 Sep 2026 NCT07806266
● Recruiting Phase I Neurology
SIZOMUS Safety of Ixazomib Targeting Plasma Cells in Multiple Sclerosis
The study seeks to investigate safety and efficacy of ixazomib (NINLARO), a proteasome inhibitor, in multiple sclerosis (MS). Participants will receive either ixazomib capsules…
08 Sep 2026 NCT03783416
● Recruiting Phase III Respiratory / COPD / Asthma
A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease
Interstitial lung disease (ILD) is a lung condition resulting in inflammation and stiffening of the lung, often associated with connective tissue diseases (CTDs). ILD…
08 Sep 2026 NCT06572384
● Recruiting Cardiology / Cardiovascular
Diagnosing Variable Primary Aldosteronism.
The goal of this observational study is to see if there is a cyclical or exaggerated diurnal variation in aldosterone production in people with…
08 Sep 2026 NCT05765786
● Recruiting Cardiology / Cardiovascular
Cerebral Protection in Aortic Arch Surgery
Aortic arch repair surgery is a technically complex and challenging procedure to treat aortic pathologies. Despite advancements in perioperative care, detrimental neurological complications occur…
08 Sep 2026 NCT04966247
● Recruiting Women's Health
Effectiveness of Nutritional Resources for Milk Donors
Trial tests whether nutritional guidance for milk donors increases beneficial fatty acids in donated breast milk.
04 Sep 2026 NCT07042009