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Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

1963 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

1963 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

active not recruiting Phase II Gastroenterology
Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis
A new drug called tilpisertib fosmecarbil tested against placebo in patients with moderate-to-severe ulcerative colitis to see if it improves symptoms by week 12.
11 Sep 2026 NCT06029972
active not recruiting Phase II
A Study of Ianalumab (VAY736) in Patients With Primary Immune Thrombocytopenia (ITP) Previously Treated With at Least Two Lines of Therapies
Ianalumab is tested in adults with hard-to-treat immune thrombocytopenia who've failed previous treatments.
11 Sep 2026 NCT05885555
● Recruiting Phase II Gastroenterology
A Novel COMBinATorial Therapy With Albumin and Enoxaparin in Patients With Decompensated Cirrhosis at High-risk of Poor Outcome (COMBAT Trial).
The goal of this clinical trial is to determine primarily whether a combinatorial therapy based on the administration of human albumin and enoxaparin is…
11 Sep 2026 NCT05895136
● Recruiting Phase II
Imeroprubart in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
A study testing whether a new drug called Imeroprubart helps adults with chronic nerve inflammation and weakness.
10 Sep 2026 NCT07032662
● Recruiting Phase II Respiratory / COPD / Asthma
Trial Comparing the Safety and Efficacy of Two Different Oral VPV Doses With Placebo as Treatment for RV in Participants With COPD
Compare the safety and efficacy of two different oral vapendavir doses with placebo in order to determine the appropriate dose of vapendavir to reduce…
10 Sep 2026 NCT07610395
● Recruiting Phase II Respiratory / COPD / Asthma
Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)
BTI-203 is a randomized, double-blind, placebo-controlled, multicenter, Phase 2 proof-of-concept (POC) study to evaluate the efficacy and safety of rhu-pGSN plus standard of care…
10 Sep 2026 NCT05947955
● Recruiting Phase II Respiratory / COPD / Asthma
A Study to Investigate the Efficacy and Safety of SC0032, a Magnesium Salt Oral Spray, in Adults With Refractory or Unexplained Chronic Cough
This is a randomized placebo-controlled, parallel-arm study to determine the safety and efficacy of SC0032 in participants with RCC
10 Sep 2026 NCT07690059
● Recruiting Phase II Dermatology
A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C)
Brenipatide injections tested against placebo in patients with constipation-type irritable bowel syndrome over 35 weeks for safety and effectiveness.
08 Sep 2026 NCT07545772
active not recruiting Phase II Oncology
Study of Novel Treatment Combination Therapies in Participants With Head and Neck Squamous Cell Carcinoma Regardless of PD-L1 Expression Status; Substudy-01
Trial comparing two immunotherapy combinations with chemotherapy for advanced head and neck cancer, regardless of PD-L1 status.
03 Sep 2026 NCT06727565
● Recruiting Phase II Oncology
Irinotecan-ChemoSeed in Surgically Resectable Glioblastoma
What is being tested: Irinotecan-ChemoSeed, a locally-delivered chemotherapy implant, is being evaluated for safety, tolerability, and maximum tolerated dose (MTD) in patients undergoing surgical…
03 Sep 2026 NCT07356973
active not recruiting Phase II Oncology
A Study of the Safety and Efficacy of Various Combinations of Avelumab as Therapy in Locally Advanced or Metastatic Urothelial Carcinoma (JAVELIN Bladder Medley)
Avelumab combined with other cancer drugs was tested as maintenance therapy in advanced bladder cancer to assess safety and effectiveness.
01 Sep 2026 NCT05327530
active not recruiting Phase II Gastroenterology
A Phase 2a/b Study of the Efficacy and Safety of Subcutaneous Amlitelimab in Adults With Nonresponsive Celiac Disease
A trial testing whether amlitelimab injection reduces intestinal damage in adults with celiac disease unresponsive to gluten-free diet alone.
31 Aug 2026 NCT06557772
active not recruiting Phase II Gastroenterology
A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis
Combining two biologic drugs (guselkumab and golimumab) tested for treating ulcerative colitis in patients who haven't responded to other treatments.
28 Aug 2026 NCT05242484
active not recruiting Phase II Gastroenterology
A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn’s Disease
Testing whether combining two existing Crohn's drugs works better than either drug alone at 48 weeks.
28 Aug 2026 NCT05242471
● Recruiting Phase II Oncology
Testing Ivonescimab Versus FOLFOX in Advanced Biliary Tract Cancer Patients
What is being tested: Ivonescimab (a PD-L1/CTLA-4 bispecific antibody) is being compared against standard FOLFOX chemotherapy in patients with advanced biliary tract cancer who…
28 Aug 2026 NCT06529718
active not recruiting Phase II / Phase III Dermatology
Long-Term Safety and Efficacy Evaluation of Amlitelimab in Participants of Previous Amlitelimab Moderate to Severe Atopic Dermatitis Clinical Trials
Long-term safety and efficacy study of amlitelimab for moderate-to-severe atopic dermatitis, including drug withdrawal to assess treatment durability.
27 Aug 2026 NCT05492578
active not recruiting Phase II Diabetes / Metabolic
HM15136 (Efpegerglucagon) Treatment for 8 Weeks in Subjects Aged ≥2 Years With Congenital Hyperinsulinism (CHI)
Eight-week study testing weekly injections of HM15136 as add-on treatment for children with congenital hyperinsulinism who remain hypoglycaemic.
26 Aug 2026 NCT04732416
active not recruiting Phase II
A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Sclerosing Cholangitis (PSC)
Volixibat tested for reducing itching in patients with PSC and potentially slowing disease progression.
26 Aug 2026 NCT04663308
active not recruiting Phase I / Phase II Oncology
Study of AZD5305 When Given in Combination With New Hormonal Agents in Patients With Metastatic Prostate Cancer
Trial testing whether combining AZD5305 with hormone therapies is safe and effective for advanced prostate cancer.
26 Aug 2026 NCT05367440
active not recruiting Phase II Oncology
Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)
Entrectinib treats solid cancers with specific genetic fusions (NTRK, ROS1, ALK), grouped by cancer type and mutation.
25 Aug 2026 NCT02568267
active not recruiting Phase II
Study to Evaluate Tulisokibart for Hidradenitis Suppurativa (MK-7240-012)
Tulisokibart tested against placebo in moderate-to-severe skin infection; primary outcome was 50% symptom improvement at 16 weeks.
25 Aug 2026 NCT06956235
● Recruiting Phase II Rheumatology
A Study of Zasocitinib (TAK-279) in Adults With Active Crohn’s Disease
What is being tested: Zasocitinib (TAK-279), an investigational therapy targeting cellular and molecular mechanisms of inflammation, is being evaluated for its efficacy in treating…
24 Aug 2026 NCT07403968
● Recruiting Phase II Respiratory / COPD / Asthma
Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Idiopathic Pulmonary Fibrosis
What is being tested: ABBV-142, an investigational therapeutic agent, is being evaluated for its safety profile and effects on disease progression in adult patients…
24 Aug 2026 NCT07230288
active not recruiting Phase II Oncology
A Study to Learn About the Study Medicine Called PF-07220060 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment
Trial testing PF-07220060 with fulvestrant versus standard treatment in advanced hormone-receptor-positive breast cancer.
20 Aug 2026 NCT06105632
● Recruiting Phase II Gastroenterology
Efficacy and Safety of Vamifeport in Adult Participants With Homeostatic Iron Regulator Gene (HFE)-Related Hereditary Hemochromatosis
Vamifeport reduced liver iron levels in adults with hereditary hemochromatosis, a genetic iron overload disorder.
20 Aug 2026 NCT07332091
active not recruiting Phase II
Study of Efficacy and Safety of Tisagenlecleucel in HR B-ALL EOC MRD Positive Patients
Tisagenlecleucel CAR-T cell therapy for high-risk B-cell leukaemia patients with minimal residual disease after initial treatment.
19 Aug 2026 NCT03876769
● Recruiting Phase II Dermatology
Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis
Multi-drug trial testing new treatments for moderate to severe eczema in adults.
19 Aug 2026 NCT06947993
active not recruiting Phase II Rheumatology
A Study Evaluating the Efficacy and Safety of Afimetoran Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)
Trial testing whether a new drug called Afimetoran works better than placebo for treating active lupus.
17 Aug 2026 NCT04895696
● Recruiting Phase II Oncology
A PoC Study to Evaluate Treatments’ Efficacy by Monitoring MRD Using ctDNA in HR-positive/HER2-negative EBC Population
What is being tested: A phase II study evaluating adjuvant treatment efficacy in HR-positive/HER2-negative early breast cancer by using circulating tumour DNA (ctDNA) as…
17 Aug 2026 NCT05708235
● Recruiting Phase II Oncology
DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.
Treatment Being Tested: The combination of dabrafenib (a BRAF inhibitor) and trametinib (a MEK inhibitor) in patients with BRAF V600 mutation-positive cancers across multiple…
17 Aug 2026 NCT07440290
● Recruiting Phase II Oncology
A Study to Find Out if Enfortumab Vedotin Given With Pembrolizumab Helps People With Muscle-invasive Bladder Cancer Keep Their Bladder
What is being tested: The combination of enfortumab vedotin (an antibody-drug conjugate targeting Nectin-4) with pembrolizumab (a PD-1 checkpoint inhibitor) as a bladder-preserving alternative…
17 Aug 2026 NCT07475806
● Recruiting Phase II / Phase III Oncology
A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma
Trial testing new drug telisotuzumab adizutecan combined with chemotherapy versus standard treatment for advanced pancreatic cancer.
14 Aug 2026 NCT07490301
active not recruiting Phase I / Phase II Oncology
Safety and Pharmacokinetics of ODM-208 in Patients With Metastatic Castration-resistant Prostate Cancer
ODM-208 showed acceptable safety in advanced prostate cancer patients, supporting further development of this new treatment.
14 Aug 2026 NCT03436485
active not recruiting Phase II / Phase III
A Study to Assess the Efficacy and Safety of Weekly Doses of GLM101 in Participants With PMM2-CDG
Weekly GLM101 treatment tested against placebo for a rare genetic disorder affecting protein processing in children and adults.
14 Aug 2026 NCT06892288
● Recruiting Phase II Respiratory / COPD / Asthma
Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis
What is being tested: CSL889 (human hemopexin) administered intravenously in a phase 2 randomized controlled trial to evaluate safety, efficacy, and pharmacokinetics in managing…
14 Aug 2026 NCT06699849
● Recruiting Phase II Cardiology / Cardiovascular
A Study of TAK-755 in Adults With Acute Ischemic Stroke
What is being tested: TAK-755, an investigational therapeutic agent, is being evaluated for safety and efficacy in treating acute ischemic stroke caused by blood…
14 Aug 2026 NCT07392450
● Recruiting Phase I / Phase II Neurology
A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)
Gene therapy AVB-101 delivered to the brain as one-time treatment for early-onset dementia caused by progranulin protein deficiency.
13 Aug 2026 NCT06064890
active not recruiting Phase II Oncology
ADP-A2M4CD8 Monotherapy and in Combination With Nivolumab in HLA-A2+ Subjects With MAGE-A4 Positive Ovarian Cancer (SURPASS-3)
SURPASS-3 Trial Summary A phase 2 trial testing a new cell therapy alone or combined with immunotherapy in women with recurrent ovarian cancer.
12 Aug 2026 NCT05601752
active not recruiting Phase II Neurology
A Study to Evaluate the Safety and Biomarker Effects of RO7269162 in Participants at Risk for or at the Prodromal Stage of Alzheimer’s Disease (AD)
Testing RO7269162 drug versus placebo in people with early-stage Alzheimer's disease brain changes over 90 weeks.
12 Aug 2026 NCT06402838
● Recruiting Phase II
A Study to Evaluate the Pharmacokinetics and Safety of Etavopivat in Pediatric Patients With Sickle Cell Disease
Trial testing a new sickle cell drug in children to check how the body processes it and whether it's safe over 96 weeks.
12 Aug 2026 NCT06198712
● Recruiting Phase II / Phase III
A Study of Efgartigimod IV in Participants From 12 Years to Less Than 18 Years of Age With Chronic Immune Thrombocytopenia (ITP)
Trial testing efgartigimod IV dosing in teenagers with chronic immune thrombocytopenia to find correct treatment dose.
12 Aug 2026 NCT07194850
● Recruiting Phase II Infectious Disease
Prevention of Recurrent C. Difficile Infection Study With AZD5148 Monoclonal Antibody
AZD5148 antibody reduces repeat Clostridioides difficile infections in adults compared to placebo.
12 Aug 2026 NCT07285213
● Recruiting Phase II
Phase 2 Study to Assess the Safety, PK, and PD of Sonefpeglutide (HM15912) in SBS-IF Subjects
A drug (sonefpeglutide) tested in patients with severe bowel disease to see if injections are safe and effective.
12 Aug 2026 NCT04775706
● Recruiting Phase I / Phase II
Study of SRP-1003 in Participants With Type 1 Myotonic Dystrophy
Gene therapy SRP-1003 tested for safety and effectiveness in patients with type 1 myotonic dystrophy.
11 Aug 2026 NCT06138743
active not recruiting Phase II
Phase 2 Study of ALXN2030 in Patients With Antibody-Mediated Rejection After Kidney Transplantation
ALXN2030 drug tested against placebo to see if it improves kidney damage from antibody rejection in transplant patients.
11 Aug 2026 NCT06744647
● Recruiting Phase II Cardiology / Cardiovascular
A Study to Learn About the Safety and Effects of the Study Drug PRX-102 in Children and Adolescents With Fabry Disease
What is being tested: PRX-102, a novel therapeutic agent, is being evaluated for safety and efficacy in the paediatric population (children and adolescents) with…
11 Aug 2026 NCT06328608
● Recruiting Phase II
A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy
Trial testing ARGX-119 injections in children aged 5-17 with spinal muscular atrophy alongside standard treatment.
10 Aug 2026 NCT07287982
active not recruiting Phase II Gastroenterology
A Gene Delivery Study to Evaluate the Safety and Expression of Delandistrogene Moxeparvovec in Participants Under the Age of Four With Duchenne Muscular Dystrophy (DMD)
Gene therapy trial testing safety and effectiveness of a new treatment for very young children with Duchenne muscular dystrophy over five years.
10 Aug 2026 NCT06128564
active not recruiting Phase II Gastroenterology
A Study to Evaluate the Long-Term Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn’s Disease
A trial testing two maintenance doses of TEV-48574 injection to keep moderate-to-severe ulcerative colitis or Crohn's disease under control long-term.
07 Aug 2026 NCT05668013
● Recruiting Phase II Oncology
Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors
Treatment being tested: Zanzalintinib (a novel investigational agent) is being compared directly against everolimus (current standard of care) in patients with advanced neuroendocrine tumors…
07 Aug 2026 NCT06943755