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Clinical Trial ● Currently Recruiting Phase II NCT07545759

A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Diarrhea (IBS-D)

A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Diarrhea (IBS-D) — Recruiting • Phase II • Dermatology • NCT07545759.

📅 13 May 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Phase II
NCT ID
NCT07545759
Start
2026-05-06
Completion
2027-09
ClinicaliQ Trial Snapshot
  • A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Diarrhea (IBS-D) — Recruiting • Phase II • Dermatology • NCT07545759.
  • A 35-week trial testing whether brenipatide injections improve symptoms and are safe in patients with IBS-diarrhea compared to placebo.

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What This Trial Is Studying

The purpose of this study is to evaluate how well brenipatide (LY3537031) is tolerated, what side effects may occur, and the safety and efficacy in participants with Irritable Bowel Syndrome-Diarrhea (IBS-D). The study drug will be administered subcutaneously (SC) (under the skin) when compared with placebo. The study will last approximately 35 weeks. Conditions: Irritable Bowel Syndrome, Diarrhea Interventions: LY3537031, Placebo Lead Sponsor: Eli Lilly and Company Planned Enrollment: 531 participants

Full Trial Details
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Eligibility criteria, protocol, and results when available
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