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Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

1003 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

1003 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

active not recruiting Phase II
A Study to Evaluate Tabelecleucel in Participants With Epstein Barr Virus (EBV) Associated Diseases
A trial testing a new cell therapy (tabelecleucel) to treat diseases caused by Epstein-Barr virus infection.
27 Apr 2026 NCT04554914
● Recruiting Phase II / Phase III
A Study to Investigate the Efficacy and Safety of Frexalimab Versus Tacrolimus in Adults Undergoing Kidney Transplantation
Frexalimab injections compared to tacrolimus tablets in first kidney transplant patients over five years to assess effectiveness and safety.
27 Apr 2026 NCT07412470
● Recruiting Phase I / Phase II
A Study of Roginolisib in Combination With Ruxolitinib in Patients With Myelofibrosis (MF) Who Are Unresponsive to JAK Inhibitors
Testing whether adding roginolisib to ruxolitinib safely improves outcomes in myelofibrosis patients who haven't responded to JAK inhibitors alone.
27 Apr 2026 NCT06887803
● Recruiting Phase II Rheumatology
Obe-cel in Severe, Refractory Systemic Lupus Erythematosus With Active Lupus Nephritis
This trial aims to find out if obe-cel gets rid of harmful B cells that contribute to systemic lupus erythematosus (SLE)/lupus nephritis (LN) when…
27 Apr 2026 NCT07053800
● Recruiting Phase II Cardiology / Cardiovascular
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy
FORTITUDE-HCM is a global, multicenter, double-blind, parallel-group, placebo-controlled Phase 2b study that will assess the efficacy and safety of ninerafaxstat compared to placebo on…
27 Apr 2026 NCT07023614
● Recruiting Phase II Oncology
DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers
This study is open to adults with small cell lung cancer and other neuroendocrine tumours. The study is in people with advanced cancer for…
27 Apr 2026 NCT05882058
● Recruiting Phase II Oncology
A Study of Efgartigimod PH20 SC in Children Between 2 and Less Than 18 Years of Age With Generalized Myasthenia Gravis
The purpose of this study is to measure the pharmacokinetics (PK), pharmacodynamics (PD), safety, tolerability, and immunogenicity of efgartigimod PH20 SC in pediatric participants…
27 Apr 2026 NCT06392386
● Recruiting Phase I / Phase II
Study of KITE-363 or KITE-753 in Participants With Relapsed and/or Refractory B-cell Lymphoma
Trial testing two new cell therapies (KITE-363 and KITE-753) for B-cell lymphoma that hasn't responded to standard treatment.
24 Apr 2026 NCT04989803
active not recruiting Phase II
A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes (LR-MDS)
A trial testing whether tebapivat reduces blood transfusion needs in patients with low-risk bone marrow disorders.
24 Apr 2026 NCT05490446
active not recruiting Phase II / Phase III
An International, Multicenter, Randomized, Double-Blind, Parallel Group, Vehicle-Controlled, Phase 2/3 Study With Open-Label Extension Evaluating the Efficacy and Safety of Diacerein 1% Ointment for the Treatment of Generalized Epidermolysis Bullosa Simplex (EBS)
Diacerein ointment tested for safety and effectiveness in treating generalized epidermolysis bullosa simplex blistering disorder.
24 Apr 2026 NCT06073132
active not recruiting Phase I / Phase II Oncology
A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer
Trial testing durvalumab combinations versus standard chemotherapy in patients with advanced triple negative breast cancer.
24 Apr 2026 NCT03742102
● Recruiting Phase II Dermatology
A Dose-ranging Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Galvokimig in Adult Study Participants With Atopic Dermatitis
Trial testing different doses of galvokimig versus placebo in adults with moderate-to-severe eczema to find the most effective safe dose.
24 Apr 2026 NCT07277660
● Recruiting Phase II Respiratory / COPD / Asthma
Imlifidase Prior to Kidney Transplant in Highly Sensitised Children
What is being tested: Imlifidase, an IgG-degrading enzyme, is being evaluated for its efficacy and safety in enabling successful kidney transplantation in highly sensitized…
24 Apr 2026 NCT05753930
● Recruiting Phase II Oncology
Safety and Preliminary Efficacy of Pumitamig (BNT327), an Investigational Therapy for Patients With Non-small Cell Lung Cancer in Combination With Chemotherapy as First-line or Second-line Treatment
What is being tested: Pumitamig (BNT327), a novel investigational therapy, combined with chemotherapy as first-line or second-line treatment in advanced/metastatic NSCLC, with evaluation of…
24 Apr 2026 NCT06841055
● Recruiting Phase II / Phase III
A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)
A trial testing whether an oral cholesterol-lowering drug is safe and effective in children and teenagers with familial high cholesterol.
23 Apr 2026 NCT07058077
active not recruiting Phase II / Phase III
A Study Evaluating the Efficacy and Safety of Mitapivat (AG-348) in Participants With Sickle Cell Disease (RISE UP)
Mitapivat tested in sickle cell patients to increase haemoglobin levels and reduce painful crisis episodes compared to placebo.
23 Apr 2026 NCT05031780
active not recruiting Phase II
A Dose-Finding Study of Tebapivat to Assess Efficacy, and Safety in Participants With Sickle Cell Disease (SCD)
Trial testing tebapivat against placebo in sickle cell disease patients to find the best dose for improving hemoglobin levels.
23 Apr 2026 NCT06924970
active not recruiting Phase II Rheumatology
An Adaptive Phase 2a/2b Study of LY3871801 in Adult Participants With Rheumatoid Arthritis
A new drug (LY3871801) is being tested for safety and effectiveness in adults with moderate-to-severe rheumatoid arthritis.
23 Apr 2026 NCT05848258
● Recruiting Phase II Respiratory / COPD / Asthma
A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma
What is being tested: KT-621, an oral investigational agent, is being evaluated in a Phase 2b trial to assess its safety and efficacy in…
23 Apr 2026 NCT07323654
● Recruiting Phase II Oncology
DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With HER2 Amplification or Activating Mutations
What is being tested: The efficacy and safety of combined trastuzumab and pertuzumab (two HER2-targeted monoclonal antibodies) across multiple cancer types with HER2 amplification…
23 Apr 2026 NCT05786716
● Recruiting Phase II Infectious Disease
A Clinical Trial of Extended (High) Treatment Dose Antibiotics in Combination With Methenamine Hippurate Compared to the Standard of Care (Either Prophylactic (Low) Dose Antibiotic Treatment or Methenamine Hippurate) in Females With Chronic Urinary Tract Infection
What is being tested: Extended high-dose antibiotic treatment combined with methenamine hippurate versus standard care (low-dose prophylactic antibiotics or methenamine hippurate alone) for managing…
23 Apr 2026 NCT07202949
● Recruiting Phase II Oncology
A Study of Novel Agents or Combinations as Perioperative Treatment in Participants With Locally Advanced Resectable Gastroesophageal Adenocarcinoma
What is being tested: Novel agents or novel combination therapies administered perioperatively (before and after surgery) in patients with locally advanced resectable gastric, gastroesophageal…
23 Apr 2026 NCT07069712
● Recruiting Phase I / Phase II
Safety, Tolerability, PK and PD of ADX-038 in Healthy Participants and Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients
ADX-038, a new drug for rare blood disorder PNH, was tested for safety and effectiveness in healthy people and patients.
22 Apr 2026 NCT05876312
● Recruiting Phase II
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves’ Disease
New drug IMVT-1402 tested against placebo in adults with Graves' disease uncontrolled by standard thyroid medications.
22 Apr 2026 NCT06727604
● Recruiting Phase II
A Study of Momelotinib in Participants With Low-risk Myelodysplastic Syndrome
Momelotinib tested for safety and effectiveness in reducing blood transfusion needs in early-stage myelodysplastic syndrome patients.
22 Apr 2026 NCT06847867
● Recruiting Phase II
Study of ALXN1920 in Adult Participants With Primary Membranous Nephropathy (PMN)
ALXN1920 (a complement C3 inhibitor) is being tested against placebo in adults with primary membranous nephropathy, with efficacy measured by reduction in 24-hour urine…
22 Apr 2026 NCT07157787
● Recruiting Phase II
Phase 2 Study of ADX-038 in Complement-Mediated Kidney Disease
Drug being tested: ADX-038, a novel therapeutic agent targeting complement-mediated pathways, is being evaluated for safety, efficacy, and how the body processes and responds…
22 Apr 2026 NCT06989359
● Recruiting Phase II
Osteogenesis Imperfecta Trial of AGA2115 for ADUlts With COL1A1 and/or COL1A2 GeNetic Variations (IDUN)
AGA2115 tested against placebo in adults with osteogenesis imperfecta caused by COL1A1 or COL1A2 gene mutations.
21 Apr 2026 NCT07062588
active not recruiting Phase I / Phase II Oncology
Durvalumab and Tremelimumab for Pediatric Malignancies
Study testing safe doses of two immunotherapy drugs in children with advanced cancers, then checking if they work.
21 Apr 2026 NCT03837899
● Recruiting Phase II Rheumatology
A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)
Tulisokibart (MK-7240) is being tested to see if it can improve symptoms of radiographic axial spondyloarthritis better than placebo.
20 Apr 2026 NCT07133633
active not recruiting Phase II
Extended Access of Momelotinib in Adults With Myelofibrosis
Momelotinib Extended Access Trial Summary This study provides ongoing access to momelotinib for myelofibrosis patients and monitors long-term safety and survival.
20 Apr 2026 NCT03441113
active not recruiting Phase I / Phase II
Safety and Tolerability of BION-1301 in Healthy Volunteers and Adults With IgA Nephropathy (IgAN)
BION-1301 was tested for safety and tolerability in healthy people and IgA kidney disease patients.
20 Apr 2026 NCT03945318
● Recruiting Phase II Oncology
A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer
The main purpose of this study is to evaluate the safety and efficacy of novel study interventions and combinations in participants with Colorectal Cancer…
20 Apr 2026 NCT06792695
● Recruiting Phase II Rheumatology
Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V
The overall purpose of this two-part study is to evaluate the efficacy, safety and tolerability of iptacopan (LNP023) in addition to standard of care…
20 Apr 2026 NCT05268289
● Recruiting Phase II Women's Health
A Phase 2 Trial to Investigate Efficacy and Safety of Vipoglanstat in Women With Endometriosis
A study testing whether vipoglanstat reduces pelvic pain in women with endometriosis, beyond pain linked to periods.
17 Apr 2026 NCT07260669
active not recruiting Phase II
A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy
Trial testing whether BI 764524 injection helps moderate-to-severe diabetic retinopathy, comparing different dosing schedules against sham control.
17 Apr 2026 NCT06321302
● Recruiting Phase I / Phase II
A Study of Pirtobrutinib in Participants With Immune Thrombocytopenia
Phase 1/2 trial testing oral pirtobrutinib for immune thrombocytopenia, evaluating safety, tolerability, and effectiveness at different doses.
17 Apr 2026 NCT06721013
● Recruiting Phase II Oncology
NEOadjuvant PembRolizumab In Stratified Medicine – ColoRectal Cancer
What is being tested: Neoadjuvant pembrolizumab (an anti-PD-1 immunotherapy) combined with standard chemotherapy and/or radiotherapy in stratified cohorts of early-stage colorectal cancer patients, assessed…
17 Apr 2026 NCT05197322
● Recruiting Phase II Neurology
Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer’s Disease Dementia
What is being tested: EXV-802 and EXV-801 are novel investigational agents being evaluated for their safety and efficacy in treating agitation symptoms in patients…
17 Apr 2026 NCT07284472
● Recruiting Phase II Oncology
Study of Novel Immunomodulators as Monotherapy and in Combination With Anticancer Agents in Participants With Advanced Hepatobiliary Cancer
What is being tested: Novel immunomodulators administered as monotherapy and in combination with anticancer agents to evaluate their efficacy, safety, and tolerability in advanced…
17 Apr 2026 NCT05775159
● Recruiting Phase II Diabetes / Metabolic
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
What is being tested: LY3457263, a novel investigational agent, is being evaluated as an add-on therapy to semaglutide or tirzepatide in patients whose blood…
17 Apr 2026 NCT06897475
active not recruiting Phase II
A Study of Intrathecal SHP611 in Children With Metachromatic Leukodystrophy
Spinal fluid injections of SHP611 tested to slow movement decline in children with metachromatic leukodystrophy.
15 Apr 2026 NCT03771898
● Recruiting Phase II Oncology
Inobrodib, Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma
Inobrodib combined with pomalidomide and dexamethasone shows promise in treating multiple myeloma that resists standard therapies.
15 Apr 2026 NCT07096778
● Recruiting Phase II Oncology
A Phase II Clinical Trial Comparing the Efficacy of RO7198457 Versus Watchful Waiting in Patients With ctDNA-positive, Resected Stage II (High Risk) and Stage III Colorectal Cancer
This is a multi-site, open-label, Phase II, randomized, trial to compare the efficacy of RO7198457 versus watchful waiting in patients with circulating tumor DNA…
15 Apr 2026 NCT04486378
● Recruiting Phase II Diabetes / Metabolic
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Chronic Kidney Disease
This study is open to adults with chronic kidney disease (CKD) that is at risk of getting worse. People who have taken a specific…
15 Apr 2026 NCT06926660
● Recruiting Phase II Oncology
Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer
This is a prospective, open-label, multi-cohort, non-randomized, multicenter phase 2 study evaluating LN-145 in patients with metastatic non-small-cell lung cancer
15 Apr 2026 NCT04614103
● Recruiting Phase II Oncology
Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer
This is a Phase 2/3, multisite, randomized, open-label study in participants with first-line non-small cell lung cancer (NSCLC). This study includes two substudies (substudy…
15 Apr 2026 NCT06712316
● Recruiting Phase II Diabetes / Metabolic
Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease
The primary objective of the FALCON study is to evaluate the efficacy of KL1333 on selected disease manifestations of primary mitochondrial disease (PMD) following…
15 Apr 2026 NCT05650229
● Recruiting Phase II Cardiology / Cardiovascular
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis
The purpose of this study is to evaluate the efficacy, safety and tolerability of pelacarsen (TQJ230) administered subcutaneously once monthly compared to placebo in…
15 Apr 2026 NCT05646381
● Recruiting Phase I / Phase II
A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis
Early-stage trial testing a new oral drug (nuvisertib) for safety and effectiveness in myelofibrosis patients.
14 Apr 2026 NCT04176198