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Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

1963 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

1963 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

active not recruiting Phase II Infectious Disease
Study of Bepirovirsen in Participants Living With Human Immunodeficiency Virus and Chronic Hepatitis B Virus Infection (B-Focus)
Bepirovirsen compared to placebo for treating people with both HIV and hepatitis B infection, measuring effectiveness and safety.
08 Jul 2026 NCT06497504
● Recruiting Phase II Oncology
KYSA-6: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Patients With Generalized Myasthenia Gravis
What is being tested: Anti-CD19 chimeric antigen receptor T-cell (CAR-T) therapy, a genetically modified T-cell immunotherapy designed to target and eliminate CD19-expressing B cells…
08 Jul 2026 NCT06193889
active not recruiting Phase I / Phase II
A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma
New dual-targeted CAR-T cell therapy tested in relapsed/refractory B-cell lymphoma and high-risk newly diagnosed DLBCL.
06 Jul 2026 NCT05421663
active not recruiting Phase I / Phase II Oncology
An Open-Label Phase lB/II Study of Glofitamab and Atezolizumab or Polatuzumab Vedotin in Adult Patients With Relapsed/Refractory B-Cell Non-Hodgkin’s Lymphoma
Testing two new drug combinations with glofitamab in patients with relapsed/refractory B-cell lymphoma to find safe doses and assess effectiveness.
06 Jul 2026 NCT03533283
● Recruiting Phase II / Phase III
A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)
A trial testing whether a new drug (atumelnant) safely and effectively treats congenital adrenal hyperplasia in children.
06 Jul 2026 NCT07159841
● Recruiting Phase II
Randomised Treatment of Acute Pancreatitis With Infliximab: Double-blind, Placebo-controlled, Multi-centre Trial (RAPID-I)
Infliximab did not improve outcomes in acute pancreatitis compared to placebo in this randomised controlled trial.
06 Jul 2026 NCT03684278
active not recruiting Phase I / Phase II Gastroenterology
Safety and Clinical Activity of QEL-001 in A2-mismatch Liver Transplant Patients
QEL-001 Trial Summary A study testing a personalised cell therapy to help liver transplant patients accept their donor organ without long-term immunosuppression.
02 Jul 2026 NCT05234190
active not recruiting Phase II Oncology
Study of Efficacy and Safety of JDQ443 Single-agent as First-line Treatment for Patients With Locally Advanced or Metastatic KRAS G12C- Mutated Non-small Cell Lung Cancer With a PD-L1 Expression < 1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation.
JDQ443 alone as initial treatment for advanced lung cancer with KRAS G12C mutation and low immune marker or specific genetic features.
02 Jul 2026 NCT05445843
● Recruiting Phase II Respiratory / COPD / Asthma
A Study to Assess the Effectiveness and Safety of GSK3862995B in Adults With Bronchiectasis
What is being tested: GSK3862995B, a novel investigational drug, is being evaluated for its effectiveness and safety in treating bronchiectasis, alongside assessment of pharmacokinetics…
02 Jul 2026 NCT07201051
● Recruiting Phase II Oncology
A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton’s Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)
NX-5948, a novel protein degradation agent, is being tested as a potential treatment for patients with relapsed/refractory CLL/SLL who have exhausted standard therapeutic options…
02 Jul 2026 NCT07221500
● Recruiting Phase II Oncology
DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) – Master Screening Protocol
What is being tested: DETERMINE evaluates targeted cancer treatments in rare cancers or common cancers with rare genetic mutations identified through routine molecular testing,…
01 Jul 2026 NCT05722886
● Recruiting Phase II Oncology
A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
Drug being tested: Ponsegromab (a novel therapeutic agent) combined with standard systemic chemotherapy, compared to chemotherapy alone with placebo, in treatment-naïve patients with metastatic…
01 Jul 2026 NCT06989437
● Recruiting Phase I / Phase II Rheumatology
Controlling Hyperactive Immunity With Long-lived Lymphocytes
Early-stage trial testing genetically-modified immune cells to treat severe autoimmune diseases (systemic sclerosis and rheumatoid arthritis).
30 Jun 2026 NCT07473154
● Recruiting Phase II / Phase III
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
Trial comparing new eye injection tiespectus against standard aflibercept treatment for wet age-related macular degeneration.
30 Jun 2026 NCT07440225
● Recruiting Phase II
An Extension Study to Evaluate Safety and Efficacy of Atumelnant in Participants With Congenital Adrenal Hyperplasia
Long-term study testing whether atumelnant is safe and effective for treating congenital adrenal hyperplasia.
29 Jun 2026 NCT06712823
● Recruiting Phase II Neurology
A Study of AAV2-GDNF in Adults With Moderate Parkinson’s Disease (REGENERATE-PD)
What is being tested: AAV2-GDNF is a gene therapy delivered surgically to the putamen (a key brain region affected in Parkinson's Disease) to potentially…
29 Jun 2026 NCT06285643
active not recruiting Phase I / Phase II Oncology
Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)
Trial testing pembrolizumab combined with various drugs to treat advanced prostate cancer resistant to hormone therapy.
26 Jun 2026 NCT02861573
active not recruiting Phase II Infectious Disease
SOLSTICE: Combination Therapy for the Treatment of Chronic Hepatitis D Infection.
Two new drugs tested together in hepatitis D patients to check if they're safe and effective.
26 Jun 2026 NCT05461170
● Recruiting Phase II Respiratory / COPD / Asthma
A Study of How the Medicine Called “Etrasimod” Works in Children With the Gut Disease Called Ulcerative Colitis
Drug being tested: Etrasimod, a selective sphingosine-1-phosphate receptor modulator, is being evaluated for safety, efficacy, and pharmacokinetics in children aged 2 to <12 years…
26 Jun 2026 NCT07470879
● Recruiting Phase II Respiratory / COPD / Asthma
Phase IIa Trial in Participants With Asthma to Evaluate Impact of Intranasal ETH47 on Development of Asthma-related Symptoms Following Rhinovirus Challenge
Treatment being tested: Intranasal ETH47, a novel therapeutic agent administered via nasal spray, designed to prevent asthma symptom development triggered by rhinovirus infection in…
26 Jun 2026 NCT07059767
active not recruiting Phase I / Phase II Oncology
Study of Vimseltinib (DCC-3014) in Patients With Advanced Tumors and Tenosynovial Giant Cell Tumor
Early-stage trial testing vimseltinib drug in patients with advanced cancers and tenosynovial giant cell tumours to find safe doses and effectiveness.
25 Jun 2026 NCT03069469
● Recruiting Phase II
Dose-Ranging Safety, Tolerability, and Efficacy Study of AZD2373 in Participants With APOL1-Mediated Kidney Disease
What is being tested: AZD2373, a novel therapeutic agent, is undergoing dose-ranging evaluation for safety, tolerability, and efficacy specifically in APOL1-mediated kidney disease, targeting…
25 Jun 2026 NCT06824987
● Recruiting Phase II Respiratory / COPD / Asthma
A Phase IIb Study to Evaluate AZD8965 in Participants With IPF.
Treatment being tested: AZD8965 at three different doses versus placebo in patients with idiopathic pulmonary fibrosis (IPF), assessed for efficacy, safety, and tolerability, with…
25 Jun 2026 NCT07652658
● Recruiting Phase II Respiratory / COPD / Asthma
Therapeutic Equivalence of CHF5993 pMDI 100/6/12.5 µg HFA-152a in Subjects With Mild to Moderate Asthma
What is being tested: Therapeutic equivalence of CHF5993 pMDI (a combination inhaler containing beclomethasone/formoterol/glycopyrronium) formulated with HFA-152a propellant versus the standard formulation, to confirm…
25 Jun 2026 NCT07301736
● Recruiting Phase II Cardiology / Cardiovascular
A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction
What is being tested: A low-energy diet intervention to improve functional status and symptoms in patients with heart failure with preserved ejection fraction (HFpEF),…
25 Jun 2026 NCT05887271
● Recruiting Phase II Oncology
Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL
Drug being tested: Surovatamig (AZD0486), a novel monotherapy agent, is being evaluated for efficacy, safety and tolerability in treating relapsed/refractory B-cell non-Hodgkin lymphoma in…
25 Jun 2026 NCT06526793
active not recruiting Phase II Gastroenterology
Long-term Follow-up Study to Evaluate Durability of Treatment Response in Previous Bepirovirsen Study Participants (B-Sure)
B-Sure Trial Summary This study tracks how long the benefits of bepirovirsen (an experimental hepatitis B treatment) last in patients after they stop taking…
24 Jun 2026 NCT04954859
● Recruiting Phase II
A Clinical Study to Evaluate DNTH103 in Adults With Multifocal Motor Neuropathy
Phase 2 trial testing Claseprubart safety and effectiveness in adults with multifocal motor neuropathy.
23 Jun 2026 NCT06537999
active not recruiting Phase I / Phase II Oncology
Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options
Entrectinib tested in children with advanced solid or brain tumours carrying specific gene fusions to find safe doses and effectiveness.
23 Jun 2026 NCT02650401
active not recruiting Phase II Oncology
A Study of Olaparib Prior to Surgery and Chemotherapy in Ovarian, Primary Peritoneal, and Fallopian Tube Cancer
Olaparib given before surgery and chemotherapy to shrink recurrent ovarian, peritoneal, or fallopian tube cancers.
23 Jun 2026 NCT02489006
active not recruiting Phase II / Phase III Rheumatology
A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus
Litifilimab injections tested for efficacy and safety in adults with active cutaneous lupus unresponsive to antimalarial therapy.
22 Jun 2026 NCT05531565
active not recruiting Phase II
Acalabrutinib and Rituximab in Previously Untreated Mantle Cell Lymphoma
Acalabrutinib plus rituximab showed promise as a gentler first-line treatment option for elderly or frail patients with mantle cell lymphoma.
22 Jun 2026 NCT05004064
● Recruiting Phase I / Phase II Rare Diseases
A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE)
Single intravenous gene therapy infusion (SGT-003) tested for safety and effectiveness in children with Duchenne muscular dystrophy across age groups.
22 Jun 2026 NCT06138639
● Recruiting Phase II Mental Health / Psychiatry
A Phase 2a Efficacy, Safety, Tolerability, and PK Study of SYT-510 in Participants With Generalized Anxiety Disorder
Single dose of experimental drug SYT-510 tested against placebo in anxiety patients to assess safety, effectiveness and body response.
18 Jun 2026 NCT07478744
active not recruiting Phase II Rheumatology
A Study to Assess the Safety, Tolerability, and Efficacy of IMVT-1402 in Participants With Cutaneous Lupus Erythematosus (CLE)
Trial testing IMVT-1402 injection versus placebo for skin lupus, measuring safety and effectiveness over 52 weeks.
17 Jun 2026 NCT06980805
● Recruiting Phase II Neurology
A Trial to Test the Use of Dapansutrile, an Anti-inflammatory Medication, in People With Parkinson’s Disease
What is being tested: Dapansutrile, an anti-inflammatory medication that inhibits the NLRP3 inflammasome pathway, is being evaluated to determine whether reducing neuroinflammation can slow…
17 Jun 2026 NCT07157735
● Recruiting Phase II Neurology
A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years
Treatment being tested: mRNA-1195, a novel mRNA-based therapeutic, is being investigated for its safety profile and tolerability in multiple sclerosis patients, with evaluation of…
17 Jun 2026 NCT06735248
● Recruiting Phase II Respiratory / COPD / Asthma
A Study of Axatilimab at 3 Different Doses in Participants With Chronic Graft Versus Host Disease (cGVHD)
Treatment being tested: Axatilimab at three different dose levels in patients with recurrent or refractory active chronic graft versus host disease (cGVHD) who have…
17 Jun 2026 NCT04710576
active not recruiting Phase I / Phase II Gastroenterology
Study to Test the Safety and How Well Patients With Severe Hemophilia A Respond to Treatment With BAY 2599023 (DTX 201), a Drug Therapy That Delivers a Healthy Version of the Defective Factor VIII Gene Into the Nucleus of Liver Cells Using an Altered, Non-infectious Virus (AAV) as a “Shuttle”
Gene therapy trial testing safety and effectiveness of BAY 2599023 for severe hemophilia A treatment.
15 Jun 2026 NCT03588299
active not recruiting Phase II / Phase III Oncology
A Study Evaluating the Efficacy and Safety of Inavolisib + Palbociclib + Fulvestrant vs Placebo + Palbociclib + Fulvestrant in Participants With PIK3CA-Mutant, Hormone Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer
Adding inavolisib to standard breast cancer treatment improves outcomes in patients with specific genetic mutations and advanced hormone-receptor-positive disease.
15 Jun 2026 NCT04191499
active not recruiting Phase II
Naxitamab for High-Risk Neuroblastoma Patients With Primary Refractory Disease or Incomplete Response to Salvage Treatment in Bone and/or Bone Marrow
Naxitamab (anti-GD2 antibody) plus GM-CSF treats high-risk neuroblastoma resistant to initial or salvage chemotherapy, with five-year follow-up.
15 Jun 2026 NCT03363373
active not recruiting Phase I / Phase II Oncology
Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cancer
Trial testing a new breast cancer drug (elacestrant) combined with five existing treatments to find safe doses and effectiveness.
12 Jun 2026 NCT05563220
● Recruiting Phase II Oncology
Study of Olutasidenib and Temozolomide in HGG
What is being tested: Olutasidenib combined with temozolomide in newly diagnosed pediatric and young adult patients with IDH1-mutant high-grade gliomas (HGG), evaluating whether this…
12 Jun 2026 NCT06161974
active not recruiting Phase II
Study to Assess the Efficacy, Safety, and Tolerability of NOC-110 in Adults With Refractory or Unexplained Chronic Cough
New inhaled powder drug tested against placebo for treating persistent cough that hasn't responded to standard treatments.
12 Jun 2026 NCT06504446
active not recruiting Phase II Neurology
Venglustat in Combination With Cerezyme in Adult Patients With Gaucher Disease Type 3 With Venglustat Monotherapy Extension
Study tests whether adding venglustat to standard Gaucher disease treatment improves brain-related symptoms and safety in adults.
12 Jun 2026 NCT02843035
active not recruiting Phase II Respiratory / COPD / Asthma
Clairleafᵀᴹ: A Study to Test Long-term Treatment With BI 1291583 in People With Bronchiectasis Who Took Part in a Previous Study With This Medicine
Long-term safety and effectiveness study of BI 1291583 tablet in adults with bronchiectasis who completed previous trials.
12 Jun 2026 NCT05846230
● Recruiting Phase II Oncology
RO7771950 Versus Tucatinib in Combination With Trastuzumab and Capecitabine in People With Locally Advanced or Metastatic Breast Cancer That is Human Epidermal Growth Factor Receptor 2 (HER2)-Positive
Treatment being tested: RO7771950 (a novel HER2-directed tyrosine kinase inhibitor) combined with trastuzumab and capecitabine, compared against the established standard tucatinib-based regimen in HER2-positive…
12 Jun 2026 NCT07413939
● Recruiting Phase II Respiratory / COPD / Asthma
A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants
What is being tested: OHB-607, an investigational drug designed to prevent Bronchopulmonary Dysplasia (BPD) in extremely premature infants, evaluated against standard neonatal care alone…
12 Jun 2026 NCT03253263
● Recruiting Phase II Oncology
A Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Participants With Resected PDAC
What is being tested: Adjuvant autogene cevumeran (personalised neoantigen vaccine) combined with atezolizumab (PD-L1 inhibitor) plus mFOLFIRINOX chemotherapy versus mFOLFIRINOX chemotherapy alone in patients…
09 Jun 2026 NCT05968326
active not recruiting Phase II Oncology
A Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With Persistent or Recurrent Rare Epithelial Ovarian Tumors
Trial testing targeted cancer drugs based on tumour genetic markers in women with rare, recurrent ovarian cancer.
08 Jun 2026 NCT04931342