ClinicaliQ Trial Snapshot
- BAY3401016; Biomarker Study Alport — Recruiting • Phase II • NCT07211685.
- BAY3401016 is a new drug that blocks a protein to slow kidney damage progression in adults with rapidly worsening Alport syndrome.
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What This Trial Is Studying
Alport syndrome (AS) is a rare genetic condition that causes kidney disease, hearing loss, and eye abnormalities that occur due to changes in specific genes (COL4A3, COL4A4, and COL4A5). These genes help in producing an important protein called collagen. People with AS have a high risk of developing chronic kidney disease (CKD), a condition in which there is progressive loss in kidney function over time. The kidneys soon lose their ability to remove waste products from the body properly, resulting in end-stage kidney disease. A common sign of decreasing kidney…