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Clinical Trial Active — Not Recruiting Phase II NCT06703346

Study to Evaluate Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Treated Advanced (Metastatic or Unresectable) Synovial Sarcoma or Myxoid/Round Cell Liposarcoma

Study to Evaluate Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Treated Advanced (Metastatic or Unresectable) Synovial Sarcoma or Myxoid/Round Cell Liposarcoma…

📅 08 Apr 2026 ⏱ 1 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Phase II
NCT ID
NCT06703346
Start
2019-12-31
Completion
2024-03-01
ClinicaliQ Trial Snapshot
  • Study to Evaluate Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Treated Advanced (Metastatic or Unresectable) Synovial Sarcoma or Myxoid/Round Cell Liposarcoma — Active Not Recruiting • Phase II • Oncology • NCT06703346.
  • Engineered T-cell therapy trial testing safety and effectiveness in advanced synovial sarcoma or liposarcoma patients.

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What This Trial Is Studying

This trial will evaluate safety and efficacy of human engineered T-cell therapies, in participants with advanced tumors. This trial is a sub study of the Master study NCT03967223. Conditions: Neoplasms Interventions: Letetresgene autoleucel (Lete-Cel (GSK3377794)), Cyclophosphamide, Fludarabine Lead Sponsor: USWM CT, LLC Planned Enrollment: 87 participants

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
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