ClinicaliQ Trial Snapshot
- A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer — Recruiting • Phase II • Oncology • NCT05498428.
- Amivantamab injection tested for safety and effectiveness in advanced cancers, particularly lung cancer with specific genetic mutations.
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What This Trial Is Studying
The purpose of this study is to assess the anti-tumor activity and safety of amivantamab which will be administered as a co-formulation with recombinant human hyaluronidase PH20 (rHuPH20) (subcutaneous co-formulation [SC-CF]) in combination treatment (all cohorts except Cohort 4) and to characterize the safety of amivantamab SC-CF (Cohort 4). Conditions: Carcinoma, Non-small-Cell Lung Interventions: Amivantamab, Lazertinib, Carboplatin, Pemetrexed, Direct Oral Anticoagulant (DOAC), Low Molecular Weight Heparin (LMWH) Lead Sponsor: Janssen Research & Development, LLC Planned Enrollment: 520 participants