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Clinical Trial Active — Not Recruiting Phase I / Phase II NCT06116136

A Study to Evaluate the Safety and the Activity of S095029 as Part of Combination Therapy in Advanced Gastroesophageal Junction/Gastric Cancers.

A Study to Evaluate the Safety and the Activity of S095029 as Part of Combination Therapy in Advanced Gastroesophageal Junction/Gastric Cancers. — Active Not Recruiting • Phase I…

📅 03 Apr 2026 ⏱ 1 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Phase I / Phase II
NCT ID
NCT06116136
Start
2024-08-31
Completion
2027-08
ClinicaliQ Trial Snapshot
  • A Study to Evaluate the Safety and the Activity of S095029 as Part of Combination Therapy in Advanced Gastroesophageal Junction/Gastric Cancers. — Active Not Recruiting • Phase I / Phase II • Oncology • NCT06116136.
  • Review the linked registry entry for study design, population, endpoints, and operational status.

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What This Trial Is Studying

This study will investigate the safety, tolerability, and antitumor activity of S095029 (anti-NKG2A antibody) in combination with pembrolizumab in in microsatellite instability-high/Defective mismatch repair (MSI-H/dMMR) locally advanced unresectable or metastatic gastric /GEJ adenocarcinomas. Conditions: MSI-H/dMMR Gastroesophageal-junction Cancer, MSI-H/dMMR Gastric Cancer Interventions: S095029, pembrolizumab 200 mg (KEYTRUDA ®) Lead Sponsor: Servier Bio-Innovation LLC Planned Enrollment: 48 participants

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
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