Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Women's Health Rheumatology Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

2231 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

2231 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase I / Phase II Diabetes / Metabolic
A Phase 1/2a Study of WVE-007 in Adults Living With Overweight or Obesity
WVE-007 is a new injectable weight-loss drug being tested for safety and effectiveness in overweight and obese adults, with and without type 2 diabetes.
26 Oct 2026 NCT06842186
● Recruiting Phase I Respiratory / COPD / Asthma
A 2-part Phase 1/2 Open-label Trial on ODM-212
What is being tested: ODM-212 is a novel therapeutic agent being evaluated through a structured phase 1/2 trial design, progressing from initial dose escalation…
22 Oct 2026 NCT07563738
● Recruiting Phase I Oncology
A Study of MX006 in Patients With Advanced and/or Metastatic Tumors Known to Express B7-H3
What is being tested: MX006, a novel first-in-human B7-H3-targeted immunotherapy, is being evaluated in a Phase 1a/1b dose-escalation and dose-expansion study in patients with…
22 Oct 2026 NCT07807241
● Recruiting Phase I Oncology
Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors
Drug Being Tested: PF-07220060, a novel investigational agent being evaluated both as monotherapy and in combination with endocrine therapy for advanced solid tumors, with…
21 Oct 2026 NCT04557449
active not recruiting Phase I / Phase II Oncology
Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies
BT8009-100 Trial Summary First-in-human trial testing BT8009 alone and with pembrolizumab in advanced cancers expressing Nectin-4 protein.
20 Oct 2026 NCT04561362
● Recruiting Phase I Respiratory / COPD / Asthma
A Study of RO7830698 in Healthy Participants and Participants With Chronic Obstructive Pulmonary Disease
What is being tested: RO7830698, a novel therapeutic agent, is undergoing evaluation for safety, tolerability, pharmacokinetics, immunogenicity, and pharmacodynamic effects at single and multiple…
20 Oct 2026 NCT07822334
● Recruiting Phase I
Phase 1/2 Study of ABO-101 in Primary Hyperoxaluria Type 1 (redePHine)
The goal of the redePHine study is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of ABO-101 in participants with primary hyperoxaluria type 1…
19 Oct 2026 NCT06839235
● Recruiting Phase I Respiratory / COPD / Asthma
A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD
The purpose of this open-label study is to assess the safety, tolerability, pharmacodynamics, and pharmacokinetics of WVE-006 in participants with alpha-1 antitrypsin deficiency (AATD)…
19 Oct 2026 NCT06405633
● Recruiting Phase I Oncology
Study of ART6043 in Advanced/Metastatic Solid Tumors Patients (POLKA)
This interventional study will evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of ART6043 as monotherapy or in combination with olaparib.
19 Oct 2026 NCT05898399
● Recruiting Phase I Oncology
A Clinical Study of MK-4208/TERN-701 in Participants With Chronic Myeloid Leukemia (CML) (MK-4208-003/Tern701-1012/CARDINAL)
Researchers are looking for a new way to treat a blood cancer called chronic myeloid leukemia (CML). Researchers want to learn if MK-4208 (Tern-701)…
15 Oct 2026 NCT06163430
● Recruiting Phase I Respiratory / COPD / Asthma
Evaluation of Safety, Side Effects, and How the Drug, Inhaled CHF10136, Is Absorbed, Modified and Removed From the Body in Healthy Adults and Adults With Asthma
This study evaluates the safety and tolerability of CHF10136 administered by inhalation in healthy adults and adults with asthma. The study includes single-dose, multiple-dose,…
13 Oct 2026 NCT07851623
● Recruiting Phase I Oncology
AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia
This is a Phase 1/2, global multicentre, open-label, single-arm, dose escalation and dose optimization study of surovatamig (AZD0486) to evaluate the safety, tolerability, and…
13 Oct 2026 NCT06137118
● Recruiting Phase I Oncology
Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors
Drug being tested: XmAb541, an investigational immunotherapy agent, is undergoing Phase 1 evaluation to establish safety, tolerability, and optimal dosing in patients with advanced…
09 Oct 2026 NCT06276491
● Recruiting Phase I Oncology
A Study of CHM-029 in Participants With NPM1 Mutated, KMT2A or NUP98 Rearranged AML
What is being tested: CHM-029, an investigational oral medication, is being evaluated for safety and efficacy in adult patients with specific subtypes of acute…
08 Oct 2026 NCT07751991
● Recruiting Phase I Oncology
A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Patients With Bladder Cancer (MK-2870-027)
Drug being tested: Sacituzumab Tirumotecan (MK-2870), an antibody-drug conjugate targeting Trop-2, administered directly into the bladder to determine safety, tolerability, and maximum tolerated dose…
06 Oct 2026 NCT06637423
● Recruiting Phase I
First-in-Human Dose-escalation of GSK4425689A: Safety, Tolerability, and PK in Healthy Adults
Early-stage trial testing a new antibody drug's safety and how the body processes it in healthy volunteers via injection or infusion.
05 Oct 2026 NCT07646353
● Recruiting Phase I Oncology
A Study of Mocertatug Rezetecan in Combination With Anti-cancer Therapies for Advanced Solid Tumors (BEHOLD-2)
What is being tested: Mocertatug rezetecan, a novel targeted cancer therapy, combined with existing anti-cancer treatments in patients with advanced solid tumors that have…
02 Oct 2026 NCT06796907
● Recruiting Phase I Oncology
HTL0039732 in Participants With Advanced Solid Tumours
What is being tested: HTL0039732, a novel therapeutic agent, is being evaluated as monotherapy and in combination regimens with atezolizumab and other established anti-cancer…
01 Oct 2026 NCT05944237
● Recruiting Phase I Oncology
A Study Evaluating the Efficacy and Safety of Risvutatug Rezetecan in Participants With Advanced Sarcomas (EMBOLD Sarcoma-202)
Treatment being tested: Risvutatug Rezetecan (Ris-Rez), a novel therapeutic agent being evaluated for efficacy and safety in patients with advanced sarcomas, with assessment of…
01 Oct 2026 NCT07602777
active not recruiting Phase I Oncology
A Study to Test Different Doses of BI 1823911 Alone and Combined With Other Medicines in People With Different Types of Advanced Cancer With KRAS Mutation
Trial of BI 1823911 alone and combined with BI 1701963 in advanced KRAS-mutated cancers to find tolerable doses and tumour response.
30 Sep 2026 NCT04973163
active not recruiting Phase I Infectious Disease
A Study to Investigate the Use of VH3810109 With or Without Fostemsavir (FTR) to Reduce the Size and Activity of the Viral Reservoir in People Living With HIV
Trial testing VH3810109 alone or with fostemsavir to shrink and reduce HIV reservoir activity in treatment-naive and treatment-experienced patients.
28 Sep 2026 NCT07053384
● Recruiting Phase I Oncology
A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers.
What is being tested: Novel dose ramp-up schedules for sonrotoclax, a new therapeutic agent, to establish safe initiation protocols in patients with blood cancers…
28 Sep 2026 NCT06697184
active not recruiting Phase I
A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies
A trial testing a new drug (bleximenib) combined with standard AML treatments to find safe, effective doses.
25 Sep 2026 NCT05453903
active not recruiting Phase I Gastroenterology
A Study of Amivantamab Subcutaneous (SC) Administration for the Treatment of Advanced Solid Malignancies
Testing whether amivantamab can be safely given by injection under the skin instead of intravenously for treating advanced cancers.
25 Sep 2026 NCT04606381
● Recruiting Phase I Oncology
A Study of GSK5764227 in Combination With Standard of Care (SoC) or Other Agents in Participants With Advanced Solid Tumors
What is being tested: GSK5764227, a novel targeted toxin delivery agent designed to selectively kill cancer cells, is being evaluated in combination with standard-of-care…
25 Sep 2026 NCT07277270
● Recruiting Phase I Oncology
First in Human Study of CDR404 in HLA-A*02:01 Participants With MAGE-A4 Expressing Solid Tumors
What is being tested: CDR404, a novel bispecific T-cell engaging antibody that targets MAGE-A4 expressing solid tumors in HLA-A*02:01 positive patients, with evaluation of…
24 Sep 2026 NCT06402201
● Recruiting Phase I / Phase II
A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration
Single eye injection of SAR446597 tested for safety and effectiveness in age-related macular degeneration vision loss over two years.
22 Sep 2026 NCT07215234
● Recruiting Phase I
A Drug-drug Interaction Study to Assess the Effect of Phenytoin and Itraconazole on the Pharmacokinetics of Pelabresib in Healthy Participants
Phenytoin and itraconazole significantly alter pelabresib blood levels; phenytoin reduces levels while itraconazole increases them in healthy volunteers.
22 Sep 2026 NCT07783503
active not recruiting Phase I / Phase II Oncology
Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies
Early-stage trial testing whether AZD5305 PARP inhibitor works alone or combined with other cancer drugs in advanced solid tumors.
21 Sep 2026 NCT04644068
● Recruiting Phase I
A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A
Trial testing whether new medicine Inno8 is safe and effective at different doses for haemophilia A patients.
18 Sep 2026 NCT07220564
● Recruiting Phase I Gastroenterology
An Early-Stage Study in Multiple Clinics of How Afimkibart May Affect the Body’s Processing of Medicines That Rely on Cytochrome P450 Enzymes in Participants With Ulcerative Colitis
Early trial testing whether afimkibart affects how the body breaks down common medicines in ulcerative colitis patients.
18 Sep 2026 NCT07665723
● Recruiting Phase I
A Study to Evaluate ALN-4915 in Adult Healthy Volunteers
A study testing a new drug called ALN-4915 in healthy adults to check if it's safe and how the body processes it.
16 Sep 2026 NCT07535606
active not recruiting Phase I Oncology
NG-350A Plus Chemoradiotherapy for Locally Advanced Rectal Cancer
NG-350A combined with standard chemoradiotherapy improves outcomes in high-risk locally advanced rectal cancer patients.
16 Sep 2026 NCT06459869
● Recruiting Phase I
A Study to Evaluate ALN-HTT02 in Adult Patients With Huntington’s Disease
A trial testing whether a new drug (ALN-HTT02) is safe and effective in adults with Huntington's disease.
16 Sep 2026 NCT06585449
● Recruiting Phase I Oncology
A Study of CD19 Targeted CAR T Cell Therapy in Pediatric Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia (B ALL) and Aggressive Mature B-cell Non-Hodgkin Lymphoma (B NHL)
What is being tested: Autologous CAR T cell therapy engineered to target CD19 antigen in pediatric patients with relapsed or refractory B-cell acute lymphoblastic…
16 Sep 2026 NCT06173518
active not recruiting Phase I / Phase II Neurology
Brainshuttle AD: A Multiple Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7126209 Following Intravenous Infusion in Participants With Prodromal or Mild to Moderate Alzheimer’s Disease
Study testing increasing doses of RO7126209 infusions to assess safety and effectiveness in early Alzheimer's disease patients with amyloid buildup.
14 Sep 2026 NCT04639050
● Recruiting Phase I Gastroenterology
Human Mass Balance Study of [14C] Ontunisertib in Healthy Volunteers
Study tracking how the body absorbs, processes and eliminates a single dose of ontunisertib using radioactive labelling in healthy men.
11 Sep 2026 NCT07672574
● Recruiting Phase I Oncology
CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors
CR-001 monotherapy is being evaluated for safety, tolerability, and dose optimization (MTD/RP2D) in adults with locally advanced or metastatic solid tumors, representing early-stage clinical…
10 Sep 2026 NCT07335497
active not recruiting Phase I Diabetes / Metabolic
To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
Phase I trial testing inavolisib alone and combined with standard breast cancer treatments in patients with PIK3CA-mutant tumours.
08 Sep 2026 NCT03006172
● Recruiting Phase I Neurology
SIZOMUS Safety of Ixazomib Targeting Plasma Cells in Multiple Sclerosis
What is being tested: Ixazomib (NINLARO), a proteasome inhibitor licensed for multiple myeloma, is being investigated as a novel therapeutic agent to target plasma…
08 Sep 2026 NCT03783416
● Recruiting Phase I Oncology
Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration
ORIC-114 is being tested as a novel therapeutic agent either alone or combined with chemotherapy in patients with advanced solid tumors carrying EGFR or…
04 Sep 2026 NCT05315700
active not recruiting Phase I
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RG6496 in Huntington’s Disease
RG6496 is being tested in Huntington's disease gene carriers to assess its safety, tolerability, and how the body processes it.
02 Sep 2026 NCT07246941
● Recruiting Phase I Neurology
A Clinical Trial of LY3962681 in Healthy Volunteers and in Patients With Parkinson’s Disease
Drug being tested: LY3962681, a novel investigational compound undergoing evaluation for safety, tolerability, and pharmacokinetic/pharmacodynamic properties in both healthy volunteers and Parkinson's disease patients…
01 Sep 2026 NCT06565195
● Recruiting Phase I Respiratory / COPD / Asthma
To Identify if a COPD Self-management App Can Safety and Appropriately Identify When Patients Are Not on the Best Medication Plan for Their COPD Symptoms and Support Their COPD Management.
What is being tested: A COPD self-management app designed to safely and accurately identify when patients are not receiving optimal inhaled therapy for their…
01 Sep 2026 NCT07797985
● Recruiting Phase I Oncology
A Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid Tumors
What is being tested: CTIM-76, a CLDN6-directed T cell-engaging bispecific antibody, is being evaluated in a Phase 1a/1b dose escalation and expansion study to…
31 Aug 2026 NCT06515613
● Recruiting Phase I Oncology
A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer
What is being tested: Amivantamab (an EGFR/MET bispecific antibody) is being evaluated as monotherapy and in combination with pembrolizumab, paclitaxel, or pembrolizumab plus carboplatin…
28 Aug 2026 NCT06385080
● Recruiting Phase I Respiratory / COPD / Asthma
A Study to Evaluate Pharmacokinetics, Safety, and Tolerability of Two GSK3862995B Formulations in Healthy Participants
What is being tested: Two different formulations of GSK3862995B, an investigational medicine, are being compared to evaluate their pharmacokinetics (absorption, distribution, metabolism, and elimination),…
27 Aug 2026 NCT07789899
active not recruiting Phase I Gastroenterology
A First-time in Human (FTIH) Study to Evaluate Safety, Tolerability, Pharmacokinetics and Target Engagement of GSK4528287 in Healthy Participants
A new experimental drug (GSK4528287) for inflammatory bowel disease is being tested in healthy volunteers for the first time to check safety and how…
26 Aug 2026 NCT06681181
active not recruiting Phase I / Phase II Oncology
Study of AZD5305 When Given in Combination With New Hormonal Agents in Patients With Metastatic Prostate Cancer
Trial testing whether combining AZD5305 with hormone therapies is safe and effective for advanced prostate cancer.
26 Aug 2026 NCT05367440
● Recruiting Phase I Rheumatology
Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants
Early-stage trial testing a new injection drug's safety, tolerability, and how the body processes it in patients with rheumatoid arthritis or lupus.
26 Aug 2026 NCT07201558