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Clinical Trial Active — Not Recruiting Phase I NCT04886804

Beamion LUNG-1: A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene)

Beamion LUNG-1: A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene) — Active…

📅 13 May 2026 ⏱ 1 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Phase I
NCT ID
NCT04886804
Start
2021-07-02
Completion
2026-12-30
ClinicaliQ Trial Snapshot
  • Beamion LUNG-1: A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene) — Active Not Recruiting • Phase I • Oncology • NCT04886804.
  • Trial testing increasing doses of zongertinib tablet in advanced cancer with HER2 gene changes, then evaluating tumour response at tolerated dose.

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What This Trial Is Studying

The study has 2 parts. The first part is open to adults with different types of advanced cancer (solid tumours with changes in the HER2 gene) for whom previous treatment was not successful. The second part is open to people with non-small cell lung cancer with a specific mutation in the HER2 gene. The purpose of the first study part is to find the highest dose of a medicine called zongertinib the participants can tolerate. Once this dose is found, it will be used in the second study part to…

Full Trial Details
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Eligibility criteria, protocol, and results when available
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