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Clinical Trial Active — Not Recruiting Phase I NCT05990751

Multi-modular Chimeric Antigen Receptor Targeting GD2 in Neuroblastoma

Multi-modular Chimeric Antigen Receptor Targeting GD2 in Neuroblastoma — Active Not Recruiting • Phase I • NCT05990751.

📅 24 Apr 2026 ⏱ 1 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Phase I
NCT ID
NCT05990751
Start
2024-04-19
Completion
2026-12
ClinicaliQ Trial Snapshot
  • Multi-modular Chimeric Antigen Receptor Targeting GD2 in Neuroblastoma — Active Not Recruiting • Phase I • NCT05990751.
  • A trial testing a new engineered cell therapy for children with difficult-to-treat neuroblastoma, focusing on safety and feasibility.

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What This Trial Is Studying

MAGNETO is a single-centre, non-randomised, open label Phase I clinical trial of an Advanced Therapy Investigational Medicinal Product (ATIMP) in children and teenagers aged 1-16 years with relapsed or refractory neuroblastoma. The study will assess the feasibility of generating the ATIMP (GD2 CAR T cells) and the safety of administering the ATIMP in patients with relapsed or refractory neuroblastoma. Conditions: Neuroblastoma Interventions: GD2 CAR T cells Lead Sponsor: University College, London Planned Enrollment: 12 participants

Full Trial Details
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Eligibility criteria, protocol, and results when available
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