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Clinical Trial ● Currently Recruiting Phase I / Phase II NCT06887803

A Study of Roginolisib in Combination With Ruxolitinib in Patients With Myelofibrosis (MF) Who Are Unresponsive to JAK Inhibitors

A Study of Roginolisib in Combination With Ruxolitinib in Patients With Myelofibrosis (MF) Who Are Unresponsive to JAK Inhibitors — Recruiting • Phase I / Phase II •…

📅 27 Apr 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Phase I / Phase II
NCT ID
NCT06887803
Start
2025-11-17
Completion
2028-03
ClinicaliQ Trial Snapshot
  • A Study of Roginolisib in Combination With Ruxolitinib in Patients With Myelofibrosis (MF) Who Are Unresponsive to JAK Inhibitors — Recruiting • Phase I / Phase II • NCT06887803.
  • Testing whether adding roginolisib to ruxolitinib safely improves outcomes in myelofibrosis patients who haven't responded to JAK inhibitors alone.

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What This Trial Is Studying

The goal of this clinical trial is to learn how roginolisib works in comparison to standard treatment in adult patients with Myelofibrosis. The main questions it aims to answer is to evaluate the safety and tolerability of roginolisib when administered in combination with ruxolitinib. Conditions: Myelofibrosis (MF) Interventions: Roginolisib Lead Sponsor: iOnctura Planned Enrollment: 26 participants

Full Trial Details
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Eligibility criteria, protocol, and results when available
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