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Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

1963 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

1963 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase III Respiratory / COPD / Asthma
A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer’s Disease
This study will evaluate the efficacy and safety of trontinemab in participants with biomarker evidence of Alzheimer's Disease (AD) pathology but with no cognitive…
10 Sep 2026 NCT07717411
● Recruiting Phase III Diabetes / Metabolic
A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
The study will evaluate how well AZD6234 works and how safe it is in adults with excess weight or obesity. Efficacy of AZD6234 will…
10 Sep 2026 NCT07776509
● Recruiting Phase III Cardiology / Cardiovascular
Efficacy and Safety of Intranasal Cenegermin in Adult Participants With Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)
This is a phase 3, randomized, multicenter, vehicle-controlled, double-masked study to evaluate the efficacy and safety of intranasal cenegermin compared with vehicle control in…
10 Sep 2026 NCT07453888
active not recruiting Phase III Diabetes / Metabolic
A Research Study on How Well Semaglutide Helps Children and Teenagers With Excess Body Weight Lose Weight
Semaglutide weekly injections help children and teenagers lose weight better than placebo, alongside lifestyle support.
09 Sep 2026 NCT05726227
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
This is a Phase III, randomized, double-blind, parallel-group, placebo-controlled, multicenter study to investigate CV outcomes with elecoglipron compared with placebo, in adults with heart…
09 Sep 2026 NCT07761117
● Recruiting Phase III Diabetes / Metabolic
A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
This is a Phase III, randomized, double-blind, parallel-group, placebo-controlled multicenter study to investigate outcomes with elecoglipron compared with placebo in participants with CKD with…
09 Sep 2026 NCT07753993
● Recruiting Phase III Respiratory / COPD / Asthma
A Study to Investigate the Long-term Safety and Efficacy of Belimumab in Adults With Interstitial Lung Disease (ILD) Associated With Systemic Sclerosis (SSc) and Other Connective Tissue Diseases (CTD) (BLISSconneCTD-OLE)
This is an open label extension (OLE) study of an ongoing randomized controlled parent clinical studies 218224 (NCT05878717) and 221672 (NCT06572384) which aim to…
09 Sep 2026 NCT06716606
● Recruiting Phase III Cardiology / Cardiovascular
Single-arm Study of IgPro20 in Adults With Secondary Immune Deficiencies Due to Hematologic Malignancies Treated With B-cell Targeting Chimeric Antigen Receptor T-cell and T-cell Redirecting Therapies
This is a prospective, multicenter, open-label, single-arm study to assess the efficacy, safety, and pharmacokinetics (PK) of IgPro20 in adults with hematologic malignancies treated…
09 Sep 2026 NCT07648264
● Recruiting Phase III Oncology
A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)
This study aims to address the unmet medical need of participants with metastatic colorectal cancer (mCRC) who have previously been treated with irinotecan, oxaliplatin,…
09 Sep 2026 NCT07549412
● Recruiting Phase III Oncology
Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2
The purpose of this study is to evaluate the efficacy and safety of sonesitatug vedotin in combination with capecitabine with or without rilvegostomig in…
09 Sep 2026 NCT07431281
● Recruiting Phase III Respiratory / COPD / Asthma
A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease
Interstitial lung disease (ILD) is a lung condition resulting in inflammation and stiffening of the lung, often associated with connective tissue diseases (CTDs). ILD…
08 Sep 2026 NCT06572384
active not recruiting Phase III Oncology
Study of Talazoparib With Enzalutamide in Men With DDR Gene Mutated mCSPC
Adding talazoparib to enzalutamide improves outcomes in men with metastatic prostate cancer and DNA repair gene mutations.
04 Sep 2026 NCT04821622
active not recruiting Phase III
A Phase 3 Study to Assess Efficacy and Safety of Tafasitamab Plus Lenalidomide and Rituximab Compared to Placebo Plus Lenalidomide and Rituximab in Patients With Relapsed/Refractory (R/R) Follicular Lymphoma or Marginal Zone Lymphoma.
Adding tafasitamab to standard lymphoma treatment improves outcomes in patients with relapsed or refractory follicular or marginal zone lymphoma.
04 Sep 2026 NCT04680052
● Recruiting Phase III
Depemokimab in Participants With Hypereosinophilic Syndrome, Efficacy, and Safety Trial
Depemokimab added to standard care reduced flares in adults with uncontrolled hypereosinophilic syndrome over 52 weeks.
04 Sep 2026 NCT05334368
● Recruiting Phase III
A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A
Study comparing NXT007 with emicizumab for preventing bleeding in hemophilia A patients aged 12 and over.
04 Sep 2026 NCT07416604
● Recruiting Phase III Oncology
Evaluating Hormone Therapy to Achieve Optimal Doses in Metastatic Prostate Cancer
What is being tested: This phase 3 trial evaluates whether lower doses of Androgen Receptor Pathway Inhibitors (ARPIs) can achieve equivalent clinical effectiveness compared…
04 Sep 2026 NCT07751133
active not recruiting Phase III Oncology
A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy
Adding immunotherapy to standard HER2 treatment reduces breast cancer recurrence risk in patients with residual disease after pre-surgery therapy.
03 Sep 2026 NCT04873362
active not recruiting Phase III Oncology
A Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab) in Patients With Advanced or Metastatic Melanoma
Trial testing combination immunotherapy plus targeted drugs for untreated advanced melanoma with BRAF mutations.
03 Sep 2026 NCT04657991
● Recruiting Phase III
A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia
A trial testing a new drug called atumelnant in adults with a genetic condition affecting the adrenal glands to check if it works, is…
02 Sep 2026 NCT07144163
active not recruiting Phase III Oncology
Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma
Adding quemliclustat to standard chemotherapy did not improve survival in advanced pancreatic cancer compared to chemotherapy alone.
02 Sep 2026 NCT06608927
active not recruiting Phase III
SC Versus IV Isatuximab in Combination With Pomalidomide and Dexamethasone in RRMM
Trial comparing subcutaneous versus intravenous isatuximab combined with pomalidomide and dexamethasone in relapsed multiple myeloma.
02 Sep 2026 NCT05405166
● Recruiting Phase III Oncology
A Phase III Trial of BNT324 Versus Docetaxel in Metastatic Castration-resistant Prostate Cancer
What is being tested: BNT324, a novel therapeutic agent, is being evaluated against docetaxel (standard chemotherapy) combined with corticosteroids in patients with metastatic castration-resistant…
02 Sep 2026 NCT07365995
● Recruiting Phase III Cardiology / Cardiovascular
An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
What is being tested: IKT-001, a novel therapeutic agent, is being evaluated for efficacy and safety in treating WHO Group 1 pulmonary arterial hypertension…
02 Sep 2026 NCT07365332
● Recruiting Phase III Oncology
Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML
What is being tested: Revumenib (a menin inhibitor) combined with azacitidine and venetoclax in patients with newly diagnosed acute myeloid leukaemia (AML) harbouring NPM1…
02 Sep 2026 NCT06652438
active not recruiting Phase III Oncology
A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers
Testing whether zanidatamab combined with chemotherapy (with or without an immunotherapy drug) works better than standard trastuzumab treatment in advanced stomach and gullet cancers.
01 Sep 2026 NCT05152147
● Recruiting Phase III Cardiology / Cardiovascular
Long-Term, Open-label Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE
What is being tested: Once-daily oral deucrictibant extended-release tablet as a preventative treatment to reduce angioedema attack frequency in patients with hereditary angioedema (HAE),…
01 Sep 2026 NCT06679881
● Recruiting Phase III Cardiology / Cardiovascular
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
What is being tested: Zenagamtide (a novel GLP-1 receptor agonist) versus insulin glargine for glycaemic control and weight reduction in type 2 diabetes patients…
01 Sep 2026 NCT07797335
● Recruiting Phase III Oncology
A Study Evaluating the Efficacy and Safety of Inavolisib Plus Fulvestrant Compared With Alpelisib Plus Fulvestrant in Participants With HR-Positive, HER2-Negative, PIK3CA Mutated, Locally Advanced or Metastatic Breast Cancer Post CDK4/6i and Endocrine Combination Therapy
What is being tested: Inavolisib combined with fulvestrant versus alpelisib combined with fulvestrant in HR-positive, HER2-negative, PIK3CA-mutated breast cancer patients who have progressed after…
01 Sep 2026 NCT05646862
● Recruiting Phase III Oncology
Accelerated v’s Standard BEP Chemotherapy for Patients With Intermediate and Poor-risk Metastatic Germ Cell Tumours
What is being tested: Accelerated dosing schedule of BEP chemotherapy (bleomycin, etoposide, cisplatin) compared to standard dosing in men with intermediate and poor-risk metastatic…
01 Sep 2026 NCT02582697
active not recruiting Phase III Oncology
An Efficacy and Safety Study of Apalutamide (JNJ-56021927) in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone in Participants With Chemotherapy-naive Metastatic Castration-resistant Prostate Cancer (mCRPC)
Adding apalutamide to standard hormone therapy improves progression-free survival in men with advanced prostate cancer.
31 Aug 2026 NCT02257736
active not recruiting Phase III Oncology
A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions
Adding amivantamab to standard chemotherapy improves progression-free survival in advanced lung cancer with EGFR exon 20 mutations.
31 Aug 2026 NCT04538664
active not recruiting Phase III Diabetes / Metabolic
A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight
CagriSema, a new weight-loss injection, is being tested against dummy medicine and two alternatives in a 1.5-year trial, followed by observation after treatment stops.
31 Aug 2026 NCT05567796
● Recruiting Phase III Rheumatology
A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis
New drug icotrokinra tested against placebo for psoriatic arthritis in patients with and without previous biologic treatment.
28 Aug 2026 NCT06807424
active not recruiting Phase III Oncology
Sacituzumab Tirumotecan (MK-2870) in Post Platinum and Post Immunotherapy Endometrial Cancer (MK-2870-005)
New cancer drug sacituzumab tirumotecan tested against chemotherapy in previously treated endometrial cancer patients to assess survival benefits.
28 Aug 2026 NCT06132958
● Recruiting Phase III Rheumatology
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis
What is being tested: JNJ-78934804, a novel therapeutic agent, is being evaluated for efficacy and safety in treating moderately to severely active ulcerative colitis,…
28 Aug 2026 NCT07577856
● Recruiting Phase III Oncology
MK-3475A±Calderasib (MK-1084) in Completely Resected Stage IIA-IIIB (N2) KRAS G12Cm NSCLC (MK-1084-013)
What is being tested: Adjuvant calderasib (a KRAS G12C inhibitor) combined with pembrolizumab immunotherapy versus pembrolizumab alone in completely resected early-stage NSCLC with KRAS…
28 Aug 2026 NCT07431827
● Recruiting Phase III Oncology
A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer
What is being tested: TAR-210 (a novel intravesical therapeutic) is being compared against standard single-agent intravesical chemotherapy to evaluate which approach better prevents recurrence…
28 Aug 2026 NCT06319820
active not recruiting Phase II / Phase III Dermatology
Long-Term Safety and Efficacy Evaluation of Amlitelimab in Participants of Previous Amlitelimab Moderate to Severe Atopic Dermatitis Clinical Trials
Long-term safety and efficacy study of amlitelimab for moderate-to-severe atopic dermatitis, including drug withdrawal to assess treatment durability.
27 Aug 2026 NCT05492578
active not recruiting Phase III
A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With Pyruvate Kinase Deficiency (PKD) Who Are Regularly Transfused, Followed by a 5-Year Extension Period
Mitapivat reduces transfusion need in children with pyruvate kinase deficiency compared to placebo.
27 Aug 2026 NCT05144256
active not recruiting Phase III Oncology
HERTHENA-Lung02: A Study of Patritumab Deruxtecan Versus Platinum-based Chemotherapy in Metastatic or Locally Advanced EGFRm NSCLC After Failure of EGFR TKI Therapy
HERTHENA-Lung02 Summary Patritumab deruxtecan compared to chemotherapy for advanced lung cancer with EGFR mutations that stopped responding to targeted drugs.
27 Aug 2026 NCT05338970
● Recruiting Phase III
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Palmoplantar Pustulosis
Bimekizumab was tested against placebo in patients with palmoplantar pustulosis to assess its effectiveness and safety.
27 Aug 2026 NCT07219420
● Recruiting Phase III Oncology
Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
What is being tested: Daraxonrasib, a novel RAS(ON) inhibitor, evaluated both as monotherapy and in combination with gemcitabine/nab-paclitaxel (GnP) chemotherapy versus standard chemotherapy alone…
27 Aug 2026 NCT07491445
active not recruiting Phase III Neurology
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer’s Disease (TRAILBLAZER-ALZ 2)
Donanemab slows cognitive decline in early Alzheimer's disease; follow-up study monitors long-term safety and effectiveness.
26 Aug 2026 NCT04437511
active not recruiting Phase III
A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa
Long-term safety and effectiveness study of povorcitinib for moderate to severe hidradenitis suppurativa in patients completing earlier trials.
25 Aug 2026 NCT06212999
● Recruiting Phase III Oncology
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
What is being tested: Daraxonrasib (RMC-6236), a novel RAS(ON) inhibitor, is being evaluated for safety and efficacy as adjuvant therapy in resected pancreatic ductal…
25 Aug 2026 NCT07252232
active not recruiting Phase III
Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY)
Anifrolumab injection versus placebo tested in early systemic sclerosis patients to assess effectiveness and safety.
24 Aug 2026 NCT05925803
active not recruiting Phase III
A Study to Evaluate the Safety and Efficacy of Zilganersen (ION373) in Patients With Alexander Disease (AxD)
Zilganersen improves or stabilizes movement in patients with Alexander disease, a rare neurological disorder.
21 Aug 2026 NCT04849741
active not recruiting Phase III Cardiology / Cardiovascular
Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury
Botulinum toxin injections tested against placebo for treating leg stiffness after stroke or brain injury.
21 Aug 2026 NCT03992404
● Recruiting Phase III Oncology
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
What is being tested: Sofetabart Mipitecan (Sofe-M), a novel therapeutic agent being evaluated across three study parts in patients with ovarian, peritoneal, and fallopian…
21 Aug 2026 NCT07213804
active not recruiting Phase III Oncology
A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants With Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-Mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC)
Adding niraparib to standard prostate cancer treatment improves progression-free survival in men with specific DNA repair gene mutations.
20 Aug 2026 NCT04497844