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Clinical Trial ● Currently Recruiting Phase III NCT06588855

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis — Recruiting…

📅 04 May 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Phase III
NCT ID
NCT06588855
Start
2024-12-11
Completion
2027-01-30
ClinicaliQ Trial Snapshot
  • A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis — Recruiting • Phase III • Gastroenterology • NCT06588855.
  • A new drug called Afimkibart is being tested to see if it safely treats moderate to severe ulcerative colitis better than placebo.

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What This Trial Is Studying

This Phase III, multicenter, double-blind, placebo-controlled study will evaluate the efficacy and safety of induction therapy with Afimkibart (RO7790121) compared with placebo in participants with moderately to severely active ulcerative colitis (UC). Conditions: Moderately to Severely Active Ulcerative Colitis Interventions: Afimkibart, Placebo Lead Sponsor: Hoffmann-La Roche Planned Enrollment: 350 participants

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
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