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Trial Radar

1003 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

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Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase III Oncology
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer’s Disease (ADAGIO-3)
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer’s Disease (ADAGIO-3) is Recruiting • Phase III…
25 Mar 2026 NCT06937229
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN2)
A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN2) is Recruiting • Phase III • Cardiology…
25 Mar 2026 NCT06516965
● Recruiting Phase III Respiratory / COPD / Asthma
A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer’s Disease
A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer’s Disease is Recruiting • Phase III • Respiratory / COPD / Asthma •…
25 Mar 2026 NCT07170150
● Recruiting Phase III Neurology
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer’s Disease (ADEPT-3)
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer’s Disease (ADEPT-3) is Recruiting •…
25 Mar 2026 NCT05980949
● Recruiting Phase III Neurology
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer’s Disease (ADEPT-1)
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer’s Disease (ADEPT-1) is Recruiting • Phase III…
25 Mar 2026 NCT05511363
● Recruiting Phase III Oncology
A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)
A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011) is Recruiting…
25 Mar 2026 NCT06841354
● Recruiting Phase III Oncology
Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007)
Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1)…
25 Mar 2026 NCT06170788
● Recruiting Phase III Oncology
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial…
25 Mar 2026 NCT06952504
● Recruiting Phase III Oncology
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032) is Recruiting • Phase III • Oncology • NCT06966700. Researchers…
25 Mar 2026 NCT06966700
● Recruiting Phase III Oncology
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009) is Recruiting • Phase III…
25 Mar 2026 NCT06623422
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis
A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis is Recruiting • Phase III • Cardiology / Cardiovascular…
25 Mar 2026 NCT07225504
● Recruiting Phase III Cardiology / Cardiovascular
Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis
Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis is Recruiting • Phase III • Cardiology / Cardiovascular…
25 Mar 2026 NCT06141473
● Recruiting Phase III Diabetes / Metabolic
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes) is Recruiting • Phase III • Diabetes / Metabolic…
25 Mar 2026 NCT07165028
● Recruiting Phase III Diabetes / Metabolic
LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis
LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis is Recruiting…
25 Mar 2026 NCT06632444
● Recruiting Phase III Cardiology / Cardiovascular
LIVERAGE™ – Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis
LIVERAGE™ – Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis is Recruiting • Phase…
25 Mar 2026 NCT06632457
● Recruiting Phase III Gastroenterology
Study of Bitopertin in Participants With EPP or XLP (APOLLO)
Study of Bitopertin in Participants With EPP or XLP (APOLLO) is Recruiting • Phase III • Gastroenterology • NCT06910358. The goal of this clinical…
25 Mar 2026 NCT06910358
● Recruiting Phase III Respiratory / COPD / Asthma
A Phase 3 Study of Etelcalcetide in Children With Secondary Hyperparathyroidism Receiving Hemodialysis
A Phase 3 Study of Etelcalcetide in Children With Secondary Hyperparathyroidism Receiving Hemodialysis is Recruiting • Phase III • Respiratory / COPD / Asthma…
25 Mar 2026 NCT03969329
● Recruiting Phase III Cardiology / Cardiovascular
Efficacy and Safety of XyloCore Peritoneal Dialysis Solution.
Efficacy and Safety of XyloCore Peritoneal Dialysis Solution. is Recruiting • Phase III • Cardiology / Cardiovascular • NCT03994471. Randomized, controlled, parallel groups, open-label,…
25 Mar 2026 NCT03994471
● Recruiting Phase III Oncology
A Study to Assess the Efficacy and Safety of Zipalertinib Versus Placebo for Adjuvant Treatment in Participants With Stage IB-IIIA NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection
A Study to Assess the Efficacy and Safety of Zipalertinib Versus Placebo for Adjuvant Treatment in Participants With Stage IB-IIIA NSCLC With Uncommon EGFR…
25 Mar 2026 NCT07128199
● Recruiting Phase III Rheumatology
A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa
A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa is Recruiting •…
25 Mar 2026 NCT06468228
● Recruiting Phase III Oncology
A Study of Gammagard Liquid (Immune Globulin Infusion, 10%) to Prevent Infections in Adults With Multiple Myeloma
A Study of Gammagard Liquid (Immune Globulin Infusion, 10%) to Prevent Infections in Adults With Multiple Myeloma is Recruiting • Phase III • Oncology…
25 Mar 2026 NCT06980480
● Recruiting Phase III Respiratory / COPD / Asthma
Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib
Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib is Recruiting • Phase III • Respiratory / COPD / Asthma • NCT06855498.…
25 Mar 2026 NCT06855498
● Recruiting Phase III Infectious Disease
VE303 for Prevention of Recurrent Clostridioides Difficile Infection
VE303 for Prevention of Recurrent Clostridioides Difficile Infection is Recruiting • Phase III • Infectious Disease • NCT06237452. The overall objective of the RESTORATiVE303…
25 Mar 2026 NCT06237452
● Recruiting Phase III Rheumatology
A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn’s Disease
A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With…
25 Mar 2026 NCT05995353
● Recruiting Phase III Rheumatology
A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumab
A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumab…
25 Mar 2026 NCT06880744
● Recruiting Phase III Oncology
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b…
25 Mar 2026 NCT06937086
● Recruiting Phase III Oncology
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn’s Disease (MK-7240-008)
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn’s Disease (MK-7240-008) is Recruiting • Phase…
25 Mar 2026 NCT06430801
● Recruiting Phase III Cardiology / Cardiovascular
High Dose Steroids in Children With Stroke
High Dose Steroids in Children With Stroke is Recruiting • Phase III • Cardiology / Cardiovascular • NCT04873583. This clinical trial deals with focal…
25 Mar 2026 NCT04873583
● Recruiting Phase III Oncology
Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator’s Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations
Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator’s Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced…
25 Mar 2026 NCT07185997
● Recruiting Phase III Oncology
Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC
Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC is Recruiting • Phase III • Oncology • NCT06765109. Multicenter, randomized, controlled, open-label, Phase 3…
25 Mar 2026 NCT06765109
● Recruiting Phase III Cardiology / Cardiovascular
Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease
Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease is Recruiting • Phase III • Cardiology /…
25 Mar 2026 NCT05099770
● Recruiting Phase III Oncology
A Study of Retatrutide (LY3437943) in Participants With Obesity or Overweight
A Study of Retatrutide (LY3437943) in Participants With Obesity or Overweight is Recruiting • Phase III • Oncology • NCT07232719. The purpose of this…
25 Mar 2026 NCT07232719
● Recruiting Phase III Cardiology / Cardiovascular
A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults
A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults is Recruiting • Phase III…
25 Mar 2026 NCT07222137
● Recruiting Phase III Cardiology / Cardiovascular
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes is Recruiting • Phase III • Cardiology / Cardiovascular…
25 Mar 2026 NCT07321886
● Recruiting Phase III Oncology
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer is Recruiting…
25 Mar 2026 NCT06890598
● Recruiting Phase III Cardiology / Cardiovascular
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a) is Recruiting • Phase III • Cardiology / Cardiovascular •…
25 Mar 2026 NCT07157774
● Recruiting Phase III Cardiology / Cardiovascular
Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk
Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk is Recruiting • Phase III • Cardiology / Cardiovascular •…
25 Mar 2026 NCT04774159
● Recruiting Phase III Respiratory / COPD / Asthma
A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes
A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type…
25 Mar 2026 NCT07088068
● Recruiting Phase III Oncology
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation is…
25 Mar 2026 NCT06252649
● Recruiting Phase III Infectious Disease
Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation
Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance…
25 Mar 2026 NCT05243797
● Recruiting Phase III Cardiology / Cardiovascular
Study on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With Polycythemia Vera
Study on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With Polycythemia Vera is Recruiting • Phase III • Cardiology / Cardiovascular •…
25 Mar 2026 NCT06093672
● Recruiting Phase III Oncology
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer is Recruiting…
25 Mar 2026 NCT06119581