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Clinical Trial Active — Not Recruiting Phase III NCT05445778

Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer

Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer — Active Not Recruiting • Phase III • Oncology • NCT05445778.

📅 26 May 2026 ⏱ 1 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Phase III
NCT ID
NCT05445778
Start
2023-03-15
Completion
2032-05
ClinicaliQ Trial Snapshot
  • Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer — Active Not Recruiting • Phase III • Oncology • NCT05445778.
  • GLORIOSA Trial Summary.
  • Adding mirvetuximab soravtansine to bevacizumab improves outcomes in platinum-sensitive ovarian cancer with high folate receptor expression.

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What This Trial Is Studying

GLORIOSA is a Phase 3 multicenter, open label study designed to evaluate the safety and efficacy of mirvetuximab Soravtansine + Bevacizumab as maintenance therapy in participants with platinum-sensitive ovarian, primary peritoneal or fallopian tube cancers with high folate receptor-alpha (FRα) expression. Conditions: Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer Interventions: Mirvetuximab soravtansine plus Bevacizumab, Bevacizumab Lead Sponsor: AbbVie Planned Enrollment: 520 participants

Full Trial Details
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Eligibility criteria, protocol, and results when available
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