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Clinical Trial ● Currently Recruiting Phase III NCT07326709

A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington’s Disease

A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington’s Disease — Recruiting • Phase III • NCT07326709.

📅 27 May 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Phase III
NCT ID
NCT07326709
Start
2026-03-24
Completion
2030-04-02
ClinicaliQ Trial Snapshot
  • A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington’s Disease — Recruiting • Phase III • NCT07326709.
  • A trial testing whether votoplam slows Huntington's disease progression in early symptomatic patients compared with placebo.

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  • Quick orientation before opening the registry record.
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What This Trial Is Studying

The purpose is to assess safety and tolerability of votoplam and to determine whether votoplam slows disease progression in patients with early symptomatic Huntington's disease (HD) compared to the control arm. HTT227 - current compound code (former code is PTC518 from PTC Therapeutics), HTT227 is Novartis code under Novartis sponsorship. Conditions: Huntington Disease Interventions: Votoplam (blinded), Placebo Lead Sponsor: Novartis Pharmaceuticals Planned Enrollment: 770 participants

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
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