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Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

1963 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

1963 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

active not recruiting Phase III
Phase 3b Study to Assess the Efficacy, Safety, and Tolerability of Remibrutinib in Comparison to Placebo, With Omalizumab as Active Control, in Adult CSU Patients, Followed by an Open-label 52-week Optional Extension.
Remibrutinib versus placebo and omalizumab for chronic urticaria uncontrolled by antihistamines over 24-52 weeks.
19 Aug 2026 NCT06042478
● Recruiting Phase III Cardiology / Cardiovascular
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
What is being tested: Oral levosimendan efficacy and safety in patients with pulmonary hypertension combined with heart failure with preserved ejection fraction (PH-HFpEF), with…
19 Aug 2026 NCT07288398
● Recruiting Phase III Cardiology / Cardiovascular
Roll-over Study for Participants Who Have Completed a Previous Clinical Study With Benralizumab (Fasenra) and Benefit From Continued Treatment
Treatment Being Tested: Continued access to benralizumab (Fasenra), a monoclonal antibody targeting IL-5 receptor alpha, for patients with eosinophilic airway diseases who have demonstrated…
19 Aug 2026 NCT07444567
active not recruiting Phase III Oncology
Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer
Adding olaparib to abiraterone improves outcomes versus abiraterone alone in men with newly-diagnosed advanced prostate cancer.
18 Aug 2026 NCT03732820
● Recruiting Phase III Diabetes / Metabolic
A Phase 3 Study of Ersodetug in Patients With Tumor Hyperinsulinism
Study testing whether ersodetug added to standard treatment reduces low blood sugar episodes in patients with insulin-producing tumours.
17 Aug 2026 NCT06881992
● Recruiting Phase III Respiratory / COPD / Asthma
A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma
What is being tested: Depemokimab, a novel biologic therapy, is being evaluated as an add-on treatment to standard care in Type 2 asthma patients…
17 Aug 2026 NCT07456033
● Recruiting Phase III Respiratory / COPD / Asthma
Study of Oral Upadacitinib and Subcutaneous/Intravenous Tocilizumab to Evaluate Change in Disease Activity, Adverse Events and How Drug Moves Through the Body of Pediatric and Adolescent Participants With Active Systemic Juvenile Idiopathic Arthritis.
Trial testing upadacitinib tablet/liquid versus tocilizumab injection/infusion for systemic juvenile arthritis in children aged 1-18 over 52 weeks.
14 Aug 2026 NCT05609630
● Recruiting Phase II / Phase III Oncology
A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma
Trial testing new drug telisotuzumab adizutecan combined with chemotherapy versus standard treatment for advanced pancreatic cancer.
14 Aug 2026 NCT07490301
active not recruiting Phase III Oncology
A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)
Testing two new drug combinations against standard treatment for advanced kidney cancer, measuring survival and disease progression.
14 Aug 2026 NCT04736706
active not recruiting Phase II / Phase III
A Study to Assess the Efficacy and Safety of Weekly Doses of GLM101 in Participants With PMM2-CDG
Weekly GLM101 treatment tested against placebo for a rare genetic disorder affecting protein processing in children and adults.
14 Aug 2026 NCT06892288
● Recruiting Phase III Infectious Disease
A Study to Investigate Cabotegravir Ultra Long-Acting (CAB ULA) Plus Rilpivirine Ultra Long-Acting (RPV ULA) in Adults and Adolescents With HIV Who Are Virologically Suppressed
What is being tested: Cabotegravir ultra long-acting (CAB ULA) plus rilpivirine ultra-acting (RPV ULA) injections are being compared against standard long-acting formulations (CAB LA…
14 Aug 2026 NCT07650916
● Recruiting Phase III Diabetes / Metabolic
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
What is being tested: ASC30, an oral once-daily medication, is being evaluated for efficacy and safety in reducing weight and improving glycaemic control in…
14 Aug 2026 NCT07743450
● Recruiting Phase III Cardiology / Cardiovascular
Study of AZD0120 in Newly Diagnosed Multiple Myeloma Ineligible for ASCT
What is being tested: AZD0120 (a novel therapeutic agent) as consolidation/maintenance therapy following standard induction regimens (IsaVRd or DRd) compared to continuous standard therapy…
14 Aug 2026 NCT07764978
● Recruiting Phase III Oncology
A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031)
What is being tested: Sacituzumab tirumotecan (sac-TMT), an antibody-drug conjugate targeting Trop-2, is being evaluated as a potential new treatment for locally advanced or…
14 Aug 2026 NCT07419295
active not recruiting Phase III Oncology
OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer
Palazestrant versus standard hormone therapy in advanced breast cancer that's progressed on previous endocrine treatment plus CDK4/6 inhibitor.
13 Aug 2026 NCT06016738
active not recruiting Phase III Dermatology
A Research Study on How Well Concizumab Works for You if You Have Haemophilia A or B With or Without Inhibitors
Concizumab daily injections tested in haemophilia A/B patients to prevent bleeds over 2-4 years.
13 Aug 2026 NCT05135559
active not recruiting Phase III
A Study of Bomedemstat (IMG-7289/MK-3543) Compared to Best Available Therapy (BAT) in Participants With Essential Thrombocythemia and an Inadequate Response or Intolerance of Hydroxyurea (MK-3543-006)
New drug bomedemstat compared to standard treatment for essential thrombocythemia patients who don't respond to or tolerate hydroxyurea.
13 Aug 2026 NCT06079879
● Recruiting Phase III Oncology
A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)
What is being tested: Adjuvant (post-surgical) therapy combining Intismeran (V940), a personalized neoantigen vaccine, with or without pembrolizumab coformulated with berahyaluronidase alfa (MK-3475A), a…
13 Aug 2026 NCT07513376
active not recruiting Phase III Neurology
A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)
Trial testing a new drug (LP352) against placebo for seizures in children and adults with severe developmental epilepsy over two years.
12 Aug 2026 NCT06719141
● Recruiting Phase II / Phase III
A Study of Efgartigimod IV in Participants From 12 Years to Less Than 18 Years of Age With Chronic Immune Thrombocytopenia (ITP)
Trial testing efgartigimod IV dosing in teenagers with chronic immune thrombocytopenia to find correct treatment dose.
12 Aug 2026 NCT07194850
active not recruiting Phase III
An Extension Study to Investigate the Long-term Safety and Tolerability of Itepekimab in Adult Participants With Inadequately Controlled Chronic Rhinosinusitis With Nasal Polyps
Long-term safety and effectiveness study of itepekimab injections for adults with chronic nasal polyps inadequately controlled by standard treatment.
12 Aug 2026 NCT07424144
active not recruiting Phase III Gastroenterology
Evaluation of Maralixibat in Pruritus Associated With General Cholestatic Liver Disease (EXPAND)
Maralixibat safely reduced severe itching in patients with cholestatic liver disease who hadn't responded to other treatments.
11 Aug 2026 NCT06553768
● Recruiting Phase III
A Phase 3 Study to Evaluate the Safety and Efficacy of AOC 1044 (Also Referred to as Delpacibart Zotadirsen) in Participants With DMD With Gene Mutations Amenable to Exon 44 Skipping
New drug tested for Duchenne muscular dystrophy in patients whose genetic mutations can be treated by skipping exon 44.
11 Aug 2026 NCT07587242
● Recruiting Phase III Oncology
A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)
Trial testing whether mRNA vaccine plus immunotherapy reduces lung cancer recurrence after surgery in high-risk patients.
10 Aug 2026 NCT07513376
● Recruiting Phase III Gastroenterology
A Study to Assess the Pharmacokinetics, Effectiveness and Safety of Afimkibart for Induction and Maintenance Therapy in Children With Moderately to Severely Active Crohn’s Disease
Trial testing a new drug (Afimkibart) for treating moderate-to-severe Crohn's disease in children.
10 Aug 2026 NCT07298421
active not recruiting Phase III Diabetes / Metabolic
A Trial of Setmelanotide in Acquired Hypothalamic Obesity
Setmelanotide daily injections tested for weight loss and quality of life improvement in acquired hypothalamic obesity patients aged 4+ years.
10 Aug 2026 NCT05774756
● Recruiting Phase III Rheumatology
A Study of Baricitinib in Participants From 1 Year to Less Than 18 Years Old With Juvenile Idiopathic Arthritis
Baricitinib safety and effectiveness for children aged 1-17 with juvenile idiopathic arthritis.
07 Aug 2026 NCT03773965
active not recruiting Phase III Infectious Disease
A Study of the Efficacy and Safety of Risankizumab in Participants With Crohn’s Disease
Risankizumab maintains remission in moderate-to-severe Crohn's disease; studies examine dosing schedules, long-term safety, and injection device preferences.
07 Aug 2026 NCT03105102
● Recruiting Phase III
A Phase 3 Study of INCA033989 Versus Best Available Therapy in Participants With Essential Thrombocythemia
INCA033989 is tested against standard treatment in patients with essential thrombocythemia and CALR mutations who've had previous cytoreductive therapy.
06 Aug 2026 NCT07623200
● Recruiting Phase III Respiratory / COPD / Asthma
A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis
Trial testing whether nerandomilast tablet improves symptoms and slows disease in systemic sclerosis patients over one to four years.
06 Aug 2026 NCT07497087
active not recruiting Phase III Diabetes / Metabolic
Weight Loss in People Living With Overweight or Obesity Following Treatment With Cagrilintide
Experimental weight-loss injection cagrilintide tested against placebo in overweight or obese adults over 18 months.
06 Aug 2026 NCT07220642
● Recruiting Phase III
A Clinical Study to Evaluate the Effects of NXT007 Compared to Factor VIII Prophylaxis in Participants With Hemophilia A
NXT007 compared to standard Factor VIII treatment for preventing bleeding in people with moderate-to-severe hemophilia A.
06 Aug 2026 NCT07416526
● Recruiting Phase III Oncology
BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Treatment for Advanced or Metastatic Disease
What is being tested: BGB-43395 (a novel protein degrader) combined with letrozole is being compared against standard CDK4/6 inhibitors plus letrozole as first-line treatment…
06 Aug 2026 NCT07492641
● Recruiting Phase III
A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib
Trial testing whether adding elritercept to ruxolitinib improves anaemia and symptoms in myelofibrosis patients versus placebo.
05 Aug 2026 NCT07623161
active not recruiting Phase III
A Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)
Aficamten improves symptoms and exercise ability in non-obstructive hypertrophic cardiomyopathy compared to placebo.
05 Aug 2026 NCT06081894
● Recruiting Phase III Oncology
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
What is being tested: RLY-2608 (zovegalisib), a PI3K inhibitor, combined with fulvestrant is being compared against capivasertib (another PI3K inhibitor) plus fulvestrant in patients…
05 Aug 2026 NCT06982521
active not recruiting Phase III Diabetes / Metabolic
A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes
Semaglutide injection tested against placebo over five years to see if it slows diabetic eye disease in type 2 diabetes.
04 Aug 2026 NCT03811561
● Recruiting Phase III Oncology
A Study of Ifinatamab Deruxtecan in Subjects With Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC) (IDeate-Esophageal01)
Treatment being tested: Ifinatamab deruxtecan (I-DXd), a novel antibody-drug conjugate targeting DLR3, is being evaluated for efficacy and safety in patients with advanced or…
04 Aug 2026 NCT06644781
● Recruiting Phase III
A Study to Investigate the Efficacy and Safety of Apraglutide Compared With Placebo in Adult Participants With Short Bowel Syndrome Associated With Intestinal Failure (SBS-IF)
Apraglutide versus placebo for short bowel syndrome: 24-week trial testing effectiveness and safety in 124 patients.
03 Aug 2026 NCT07742735
active not recruiting Phase III Diabetes / Metabolic
Weight Loss in People Living With Overweight or Obesity and Type 2 Diabetes Following Treatment With Cagrilintide
Cagrilintide (new injection) versus placebo tested for weight loss in overweight people with type 2 diabetes over 18 months.
03 Aug 2026 NCT07220759
● Recruiting Phase III Oncology
A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)
Treatment being tested: Combination therapy of belzutifan (a HIF-2α inhibitor) and zanzalintinib (a VEGFR/TKI) in patients with recurrent advanced renal cell carcinoma following prior…
03 Aug 2026 NCT07227402
● Recruiting Phase III
A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata
Upadacitinib tablets tested for safety and effectiveness in treating severe hair loss caused by immune system attack in adolescents and adults.
31 Jul 2026 NCT06012240
● Recruiting Phase III Rheumatology
A Study to Assess Adverse Events, Change in Disease Activity, and How the Drug Moves Through the Body in Children With Juvenile Psoriatic Arthritis (jPsA) Receiving Subcutaneously Injected Risankizumab or Adalimumab
Trial comparing risankizumab versus adalimumab injections for childhood psoriatic arthritis, measuring safety and disease improvement over 124 weeks.
31 Jul 2026 NCT06100744
active not recruiting Phase III
Nipocalimab in Moderate to Severe Sjogren’s Disease
Nipocalimab injection appears safe and effective for treating moderate to severe Sjögren's disease symptoms.
31 Jul 2026 NCT06741969
● Recruiting Phase III Rheumatology
A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus
Nipocalimab reduced disease activity better than placebo in moderate-to-severe lupus patients.
31 Jul 2026 NCT07438496
active not recruiting Phase III Oncology
A Study of Nivolumab in Participants With Hepatocellular Carcinoma Who Are at High Risk of Recurrence After Curative Hepatic Resection or Ablation
Nivolumab versus placebo to prevent cancer recurrence in patients with liver cancer after surgery or ablation.
31 Jul 2026 NCT03383458
● Recruiting Phase III Oncology
A Study to Evaluate TAR-210 Versus Intravesical Chemotherapy Treatment in Participants With High Risk Non-Muscle-Invasive Bladder Cancer
What is being tested: TAR-210 (a novel therapeutic agent) is being compared against standard intravesical chemotherapy in BCG-treated patients with high-risk non-muscle-invasive bladder cancer…
31 Jul 2026 NCT06919965
active not recruiting Phase III Infectious Disease
Study to Evaluate the Efficacy, Safety, and Tolerability of Long-acting Intramuscular Cabotegravir and Rilpivirine for Maintenance of Virologic Suppression Following Switch From an Integrase Inhibitor in HIV-1 Infected Therapy Naive Participants
Two-drug long-acting injections (cabotegravir and rilpivirine) monthly maintain HIV suppression as well as daily tablets in treatment-experienced patients.
30 Jul 2026 NCT02938520
active not recruiting Phase III Oncology
Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09)
New antibody-drug conjugate T-DXd, with or without pertuzumab, compared to standard chemotherapy for HER2-positive advanced breast cancer.
30 Jul 2026 NCT04784715
active not recruiting Phase III
A Clinical Study to Assess the Efficacy and Safety of Leriglitazone in Adult Male Subjects With Cerebral Adrenoleukodystrophy
Trial testing whether leriglitazone drug slows cerebral adrenoleukodystrophy progression in adult men.
29 Jul 2026 NCT05819866