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Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

2231 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

2231 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase III Oncology
A Phase III Trial of BNT324 Versus Docetaxel in Metastatic Castration-resistant Prostate Cancer
What is being tested: BNT324, a novel therapeutic agent, is being evaluated against docetaxel (standard chemotherapy) combined with corticosteroids in patients with metastatic castration-resistant…
02 Sep 2026 NCT07365995
● Recruiting Phase III Cardiology / Cardiovascular
An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
What is being tested: IKT-001, a novel therapeutic agent, is being evaluated for efficacy and safety in treating WHO Group 1 pulmonary arterial hypertension…
02 Sep 2026 NCT07365332
● Recruiting Phase III Oncology
Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML
What is being tested: Revumenib (a menin inhibitor) combined with azacitidine and venetoclax in patients with newly diagnosed acute myeloid leukaemia (AML) harbouring NPM1…
02 Sep 2026 NCT06652438
active not recruiting Phase III Oncology
A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers
Testing whether zanidatamab combined with chemotherapy (with or without an immunotherapy drug) works better than standard trastuzumab treatment in advanced stomach and gullet cancers.
01 Sep 2026 NCT05152147
● Recruiting Phase III Cardiology / Cardiovascular
Long-Term, Open-label Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE
What is being tested: Once-daily oral deucrictibant extended-release tablet as a preventative treatment to reduce angioedema attack frequency in patients with hereditary angioedema (HAE),…
01 Sep 2026 NCT06679881
● Recruiting Phase III Cardiology / Cardiovascular
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
What is being tested: Zenagamtide (a novel GLP-1 receptor agonist) versus insulin glargine for glycaemic control and weight reduction in type 2 diabetes patients…
01 Sep 2026 NCT07797335
● Recruiting Phase III Oncology
A Study Evaluating the Efficacy and Safety of Inavolisib Plus Fulvestrant Compared With Alpelisib Plus Fulvestrant in Participants With HR-Positive, HER2-Negative, PIK3CA Mutated, Locally Advanced or Metastatic Breast Cancer Post CDK4/6i and Endocrine Combination Therapy
What is being tested: Inavolisib combined with fulvestrant versus alpelisib combined with fulvestrant in HR-positive, HER2-negative, PIK3CA-mutated breast cancer patients who have progressed after…
01 Sep 2026 NCT05646862
● Recruiting Phase III Oncology
Accelerated v’s Standard BEP Chemotherapy for Patients With Intermediate and Poor-risk Metastatic Germ Cell Tumours
What is being tested: Accelerated dosing schedule of BEP chemotherapy (bleomycin, etoposide, cisplatin) compared to standard dosing in men with intermediate and poor-risk metastatic…
01 Sep 2026 NCT02582697
active not recruiting Phase III Oncology
An Efficacy and Safety Study of Apalutamide (JNJ-56021927) in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone in Participants With Chemotherapy-naive Metastatic Castration-resistant Prostate Cancer (mCRPC)
Adding apalutamide to standard hormone therapy improves progression-free survival in men with advanced prostate cancer.
31 Aug 2026 NCT02257736
active not recruiting Phase III Oncology
A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions
Adding amivantamab to standard chemotherapy improves progression-free survival in advanced lung cancer with EGFR exon 20 mutations.
31 Aug 2026 NCT04538664
active not recruiting Phase III Diabetes / Metabolic
A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight
CagriSema, a new weight-loss injection, is being tested against dummy medicine and two alternatives in a 1.5-year trial, followed by observation after treatment stops.
31 Aug 2026 NCT05567796
● Recruiting Phase III Rheumatology
A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis
New drug icotrokinra tested against placebo for psoriatic arthritis in patients with and without previous biologic treatment.
28 Aug 2026 NCT06807424
active not recruiting Phase III Oncology
Sacituzumab Tirumotecan (MK-2870) in Post Platinum and Post Immunotherapy Endometrial Cancer (MK-2870-005)
New cancer drug sacituzumab tirumotecan tested against chemotherapy in previously treated endometrial cancer patients to assess survival benefits.
28 Aug 2026 NCT06132958
● Recruiting Phase III Rheumatology
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis
What is being tested: JNJ-78934804, a novel therapeutic agent, is being evaluated for efficacy and safety in treating moderately to severely active ulcerative colitis,…
28 Aug 2026 NCT07577856
● Recruiting Phase III Oncology
MK-3475A±Calderasib (MK-1084) in Completely Resected Stage IIA-IIIB (N2) KRAS G12Cm NSCLC (MK-1084-013)
What is being tested: Adjuvant calderasib (a KRAS G12C inhibitor) combined with pembrolizumab immunotherapy versus pembrolizumab alone in completely resected early-stage NSCLC with KRAS…
28 Aug 2026 NCT07431827
● Recruiting Phase III Oncology
A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer
What is being tested: TAR-210 (a novel intravesical therapeutic) is being compared against standard single-agent intravesical chemotherapy to evaluate which approach better prevents recurrence…
28 Aug 2026 NCT06319820
active not recruiting Phase II / Phase III Dermatology
Long-Term Safety and Efficacy Evaluation of Amlitelimab in Participants of Previous Amlitelimab Moderate to Severe Atopic Dermatitis Clinical Trials
Long-term safety and efficacy study of amlitelimab for moderate-to-severe atopic dermatitis, including drug withdrawal to assess treatment durability.
27 Aug 2026 NCT05492578
active not recruiting Phase III
A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With Pyruvate Kinase Deficiency (PKD) Who Are Regularly Transfused, Followed by a 5-Year Extension Period
Mitapivat reduces transfusion need in children with pyruvate kinase deficiency compared to placebo.
27 Aug 2026 NCT05144256
active not recruiting Phase III Oncology
HERTHENA-Lung02: A Study of Patritumab Deruxtecan Versus Platinum-based Chemotherapy in Metastatic or Locally Advanced EGFRm NSCLC After Failure of EGFR TKI Therapy
HERTHENA-Lung02 Summary Patritumab deruxtecan compared to chemotherapy for advanced lung cancer with EGFR mutations that stopped responding to targeted drugs.
27 Aug 2026 NCT05338970
● Recruiting Phase III
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Palmoplantar Pustulosis
Bimekizumab was tested against placebo in patients with palmoplantar pustulosis to assess its effectiveness and safety.
27 Aug 2026 NCT07219420
● Recruiting Phase III Oncology
Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
What is being tested: Daraxonrasib, a novel RAS(ON) inhibitor, evaluated both as monotherapy and in combination with gemcitabine/nab-paclitaxel (GnP) chemotherapy versus standard chemotherapy alone…
27 Aug 2026 NCT07491445
active not recruiting Phase III Neurology
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer’s Disease (TRAILBLAZER-ALZ 2)
Donanemab slows cognitive decline in early Alzheimer's disease; follow-up study monitors long-term safety and effectiveness.
26 Aug 2026 NCT04437511
active not recruiting Phase III
A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa
Long-term safety and effectiveness study of povorcitinib for moderate to severe hidradenitis suppurativa in patients completing earlier trials.
25 Aug 2026 NCT06212999
● Recruiting Phase III Oncology
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
What is being tested: Daraxonrasib (RMC-6236), a novel RAS(ON) inhibitor, is being evaluated for safety and efficacy as adjuvant therapy in resected pancreatic ductal…
25 Aug 2026 NCT07252232
active not recruiting Phase III
Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY)
Anifrolumab injection versus placebo tested in early systemic sclerosis patients to assess effectiveness and safety.
24 Aug 2026 NCT05925803
active not recruiting Phase III
A Study to Evaluate the Safety and Efficacy of Zilganersen (ION373) in Patients With Alexander Disease (AxD)
Zilganersen improves or stabilizes movement in patients with Alexander disease, a rare neurological disorder.
21 Aug 2026 NCT04849741
active not recruiting Phase III Cardiology / Cardiovascular
Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury
Botulinum toxin injections tested against placebo for treating leg stiffness after stroke or brain injury.
21 Aug 2026 NCT03992404
● Recruiting Phase III Oncology
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
What is being tested: Sofetabart Mipitecan (Sofe-M), a novel therapeutic agent being evaluated across three study parts in patients with ovarian, peritoneal, and fallopian…
21 Aug 2026 NCT07213804
active not recruiting Phase III Oncology
A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants With Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-Mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC)
Adding niraparib to standard prostate cancer treatment improves progression-free survival in men with specific DNA repair gene mutations.
20 Aug 2026 NCT04497844
active not recruiting Phase III
Phase 3b Study to Assess the Efficacy, Safety, and Tolerability of Remibrutinib in Comparison to Placebo, With Omalizumab as Active Control, in Adult CSU Patients, Followed by an Open-label 52-week Optional Extension.
Remibrutinib versus placebo and omalizumab for chronic urticaria uncontrolled by antihistamines over 24-52 weeks.
19 Aug 2026 NCT06042478
● Recruiting Phase III Cardiology / Cardiovascular
Roll-over Study for Participants Who Have Completed a Previous Clinical Study With Benralizumab (Fasenra) and Benefit From Continued Treatment
Treatment Being Tested: Continued access to benralizumab (Fasenra), a monoclonal antibody targeting IL-5 receptor alpha, for patients with eosinophilic airway diseases who have demonstrated…
19 Aug 2026 NCT07444567
● Recruiting Phase III Cardiology / Cardiovascular
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
What is being tested: Oral levosimendan efficacy and safety in patients with pulmonary hypertension combined with heart failure with preserved ejection fraction (PH-HFpEF), with…
19 Aug 2026 NCT07288398
active not recruiting Phase III Oncology
Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer
Adding olaparib to abiraterone improves outcomes versus abiraterone alone in men with newly-diagnosed advanced prostate cancer.
18 Aug 2026 NCT03732820
● Recruiting Phase III Diabetes / Metabolic
A Phase 3 Study of Ersodetug in Patients With Tumor Hyperinsulinism
Study testing whether ersodetug added to standard treatment reduces low blood sugar episodes in patients with insulin-producing tumours.
17 Aug 2026 NCT06881992
● Recruiting Phase III Respiratory / COPD / Asthma
A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma
What is being tested: Depemokimab, a novel biologic therapy, is being evaluated as an add-on treatment to standard care in Type 2 asthma patients…
17 Aug 2026 NCT07456033
● Recruiting Phase III Respiratory / COPD / Asthma
Study of Oral Upadacitinib and Subcutaneous/Intravenous Tocilizumab to Evaluate Change in Disease Activity, Adverse Events and How Drug Moves Through the Body of Pediatric and Adolescent Participants With Active Systemic Juvenile Idiopathic Arthritis.
Trial testing upadacitinib tablet/liquid versus tocilizumab injection/infusion for systemic juvenile arthritis in children aged 1-18 over 52 weeks.
14 Aug 2026 NCT05609630
● Recruiting Phase II / Phase III Oncology
A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma
Trial testing new drug telisotuzumab adizutecan combined with chemotherapy versus standard treatment for advanced pancreatic cancer.
14 Aug 2026 NCT07490301
active not recruiting Phase III Oncology
A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)
Testing two new drug combinations against standard treatment for advanced kidney cancer, measuring survival and disease progression.
14 Aug 2026 NCT04736706
active not recruiting Phase II / Phase III
A Study to Assess the Efficacy and Safety of Weekly Doses of GLM101 in Participants With PMM2-CDG
Weekly GLM101 treatment tested against placebo for a rare genetic disorder affecting protein processing in children and adults.
14 Aug 2026 NCT06892288
● Recruiting Phase III Infectious Disease
A Study to Investigate Cabotegravir Ultra Long-Acting (CAB ULA) Plus Rilpivirine Ultra Long-Acting (RPV ULA) in Adults and Adolescents With HIV Who Are Virologically Suppressed
What is being tested: Cabotegravir ultra long-acting (CAB ULA) plus rilpivirine ultra-acting (RPV ULA) injections are being compared against standard long-acting formulations (CAB LA…
14 Aug 2026 NCT07650916
● Recruiting Phase III Diabetes / Metabolic
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
What is being tested: ASC30, an oral once-daily medication, is being evaluated for efficacy and safety in reducing weight and improving glycaemic control in…
14 Aug 2026 NCT07743450
● Recruiting Phase III Cardiology / Cardiovascular
Study of AZD0120 in Newly Diagnosed Multiple Myeloma Ineligible for ASCT
What is being tested: AZD0120 (a novel therapeutic agent) as consolidation/maintenance therapy following standard induction regimens (IsaVRd or DRd) compared to continuous standard therapy…
14 Aug 2026 NCT07764978
● Recruiting Phase III Oncology
A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031)
What is being tested: Sacituzumab tirumotecan (sac-TMT), an antibody-drug conjugate targeting Trop-2, is being evaluated as a potential new treatment for locally advanced or…
14 Aug 2026 NCT07419295
active not recruiting Phase III Oncology
OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer
Palazestrant versus standard hormone therapy in advanced breast cancer that's progressed on previous endocrine treatment plus CDK4/6 inhibitor.
13 Aug 2026 NCT06016738
active not recruiting Phase III Dermatology
A Research Study on How Well Concizumab Works for You if You Have Haemophilia A or B With or Without Inhibitors
Concizumab daily injections tested in haemophilia A/B patients to prevent bleeds over 2-4 years.
13 Aug 2026 NCT05135559
active not recruiting Phase III
A Study of Bomedemstat (IMG-7289/MK-3543) Compared to Best Available Therapy (BAT) in Participants With Essential Thrombocythemia and an Inadequate Response or Intolerance of Hydroxyurea (MK-3543-006)
New drug bomedemstat compared to standard treatment for essential thrombocythemia patients who don't respond to or tolerate hydroxyurea.
13 Aug 2026 NCT06079879
● Recruiting Phase III Oncology
A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)
What is being tested: Adjuvant (post-surgical) therapy combining Intismeran (V940), a personalized neoantigen vaccine, with or without pembrolizumab coformulated with berahyaluronidase alfa (MK-3475A), a…
13 Aug 2026 NCT07513376
active not recruiting Phase III Neurology
A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)
Trial testing a new drug (LP352) against placebo for seizures in children and adults with severe developmental epilepsy over two years.
12 Aug 2026 NCT06719141
● Recruiting Phase II / Phase III
A Study of Efgartigimod IV in Participants From 12 Years to Less Than 18 Years of Age With Chronic Immune Thrombocytopenia (ITP)
Trial testing efgartigimod IV dosing in teenagers with chronic immune thrombocytopenia to find correct treatment dose.
12 Aug 2026 NCT07194850
active not recruiting Phase III
An Extension Study to Investigate the Long-term Safety and Tolerability of Itepekimab in Adult Participants With Inadequately Controlled Chronic Rhinosinusitis With Nasal Polyps
Long-term safety and effectiveness study of itepekimab injections for adults with chronic nasal polyps inadequately controlled by standard treatment.
12 Aug 2026 NCT07424144