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Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

1963 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

1963 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

active not recruiting Phase III Oncology
Efficacy and Safety of Pembrolizumab (MK-3475) With Platinum Doublet Chemotherapy as Neoadjuvant/Adjuvant Therapy for Participants With Resectable Stage II, IIIA, and Resectable IIIB (T3-4N2) Non-small Cell Lung Cancer (MK-3475-671/KEYNOTE-671)
Pembrolizumab plus chemotherapy before surgery, then pembrolizumab alone after surgery, improves survival in resectable lung cancer.
29 Jul 2026 NCT03425643
active not recruiting Phase III Oncology
Olaparib Treatment in BRCA Mutated Ovarian Cancer Patients After Complete or Partial Response to Platinum Chemotherapy
Olaparib vs placebo as maintenance therapy after chemotherapy in BRCA-mutated ovarian cancer patients.
29 Jul 2026 NCT01874353
active not recruiting Phase III Oncology
Study of Sacituzumab Govitecan Versus Treatment of Physician’s Choice in Participants With Endometrial Cancer After Platinum-Based Chemotherapy and Immunotherapy (ASCENT-GYN-01/GOG-3104/ENGOT-en26)
Sacituzumab govitecan improves survival compared to standard treatment in advanced endometrial cancer patients previously treated with chemotherapy and immunotherapy.
29 Jul 2026 NCT06486441
● Recruiting Phase III Respiratory / COPD / Asthma
Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)
What is being tested: Long-term safety, tolerability, and efficacy of seralutinib, an orally inhaled therapeutic agent, in patients with pulmonary arterial hypertension (PAH) who…
29 Jul 2026 NCT06274801
active not recruiting Phase III Oncology
A Global Study of Volrustomig (MEDI5752) Plus Chemotherapy Versus Pembrolizumab Plus Chemotherapy for Participants With Metastatic Non-small Cell Lung Cancer.
New drug volrustomig plus chemotherapy compared with pembrolizumab plus chemotherapy for advanced lung cancer with low PD-L1 levels.
28 Jul 2026 NCT05984277
active not recruiting Phase III Oncology
Phase III Study of AK112 for NSCLC Patients
AK112 plus chemotherapy improved outcomes in advanced lung cancer patients whose tumours had stopped responding to targeted therapy.
28 Jul 2026 NCT06396065
● Recruiting Phase III Respiratory / COPD / Asthma
eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation
What is being tested: Depemokimab, a novel therapeutic agent, is being evaluated as an add-on treatment for moderate to severe COPD patients with Type…
28 Jul 2026 NCT07177339
● Recruiting Phase III Oncology
A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer
Treatment being tested: A combination of two targeted therapies—avutometinib (a MEK inhibitor) and defactinib (a FAK inhibitor)—compared against standard investigator-selected treatments in patients with…
28 Jul 2026 NCT06072781
● Recruiting Phase III
A Study to Evaluate Del-brax (Also Referred to as AOC 1020) in Participants With FSHD
This trial tests whether intravenous AOC 1020 safely and effectively treats facioscapulohumeral muscular dystrophy compared to placebo.
27 Jul 2026 NCT07038200
active not recruiting Phase III Oncology
Study of Pembrolizumab Given Prior to Surgery and in Combination With Radiotherapy Given Post-surgery for Advanced Head and Neck Squamous Cell Carcinoma (MK-3475-689)
Pembrolizumab before and after surgery with radiotherapy improves survival in advanced head and neck cancer compared to radiotherapy alone.
27 Jul 2026 NCT03765918
active not recruiting Phase III Rheumatology
Subcutaneous Anifrolumab in Adult Patients With Systemic Lupus Erythematosus
Subcutaneous anifrolumab (an interferon-blocking drug) improved outcomes in moderate-to-severe lupus patients already on standard treatment.
27 Jul 2026 NCT04877691
● Recruiting Phase III Oncology
Clinical Trial of N-803 Plus Tislelizumab or Prior Failed Immune Checkpoint Inhibitor and Docetaxel Versus Docetaxel Monotherapy in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Acquired Resistance to Immune Checkpoint In
What is being tested: A phase 3 randomized trial comparing two experimental combination regimens (N-803 plus tislelizumab with docetaxel, or prior failed PD-1/PD-L1 checkpoint…
27 Jul 2026 NCT06745908
active not recruiting Phase III
A Study of Acalabrutinib vs Investigator’s Choice of Idelalisib Plus Rituximab or Bendamustine Plus Rituximab in R/R CLL
Acalabrutinib compared to chemotherapy plus antibody therapy for previously treated blood cancer patients.
24 Jul 2026 NCT02970318
● Recruiting Phase III Rheumatology
Apremilast Pediatric Study in Children With Active Juvenile Psoriatic Arthritis
Apremilast was tested against placebo in children aged 5-17 with juvenile psoriatic arthritis to assess its effectiveness.
24 Jul 2026 NCT04804553
active not recruiting Phase III
Open-label, Long-term Safety Study of Secukinumab in Polymyalgia Rheumatica (PMR)
Long-term safety study of secukinumab (an IL-17 inhibitor) in patients with polymyalgia rheumatica to assess tolerability and adverse effects.
24 Jul 2026 NCT06331312
● Recruiting Phase III Respiratory / COPD / Asthma
A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With Interstitial Lung Disease (FIBRONEER-chILD)
Trial testing nerandomilast tolerance and effectiveness in children aged 2-17 with interstitial lung disease over 2.5-5 years.
24 Jul 2026 NCT07366034
● Recruiting Phase III Cardiology / Cardiovascular
Apremilast Pediatric Study in Children With Active Oral Ulcers Associated With Behçet’s Disease
Intervention tested: Apremilast (a phosphodiesterase-4 inhibitor) versus placebo for treating oral ulcers in children with Behçet's disease, addressing a significant unmet need in pediatric…
24 Jul 2026 NCT04528082
● Recruiting Phase III Cardiology / Cardiovascular
Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia
Treatment tested: Inclisiran, a PCSK9 inhibitor administered via subcutaneous injection, being evaluated for its ability to lower LDL cholesterol in paediatric patients with homozygous…
24 Jul 2026 NCT06597006
● Recruiting Phase III Oncology
Vorasidenib Maintenance for IDH Mutant Astrocytoma
What is being tested: Vorasidenib (an IDH inhibitor) as maintenance therapy post-chemoradiotherapy versus placebo in IDH-mutant astrocytoma, with progression-free survival as the primary endpoint.…
24 Jul 2026 NCT06809322
active not recruiting Phase III Oncology
A Study of SGN-B6A Versus Docetaxel in Previously Treated Non-small Cell Lung Cancer
Trial comparing new cancer-targeting drug sigvotatug vedotin versus standard docetaxel chemotherapy in previously treated advanced lung cancer patients.
23 Jul 2026 NCT06012435
active not recruiting Phase II / Phase III
A Study to Examine the Efficacy and Safety of Zanubrutinib Given to Adults With Primary Membranous Nephropathy
Zanubrutinib reduced protein in urine in primary membranous nephropathy patients and was compared against standard tacrolimus treatment.
23 Jul 2026 NCT05707377
active not recruiting Phase III Oncology
Phase 3 Study of MRTX849 With Cetuximab vs Chemotherapy in Patients With Advanced Colorectal Cancer With KRAS G12C Mutation (KRYSTAL-10)
MRTX849 plus cetuximab compared to chemotherapy for advanced bowel cancer with specific KRAS mutation.
23 Jul 2026 NCT04793958
active not recruiting Phase III Oncology
A Study of Atezolizumab With or Without Tiragolumab in Participants With Unresectable Esophageal Squamous Cell Carcinoma Whose Cancers Have Not Progressed Following Definitive Concurrent Chemoradiotherapy
Trial testing whether adding tiragolumab to atezolizumab improves outcomes in advanced oesophageal cancer after chemoradiotherapy.
23 Jul 2026 NCT04543617
● Recruiting Phase III Neurology
An Evaluation of Treatments for Sustained Clinical Response (18 Months) in Symptomatic Alzheimer’s Disease
What is being tested: A Phase 3 trial evaluating multiple treatment approaches for sustained clinical response over 18 months in symptomatic Alzheimer's disease, using…
23 Jul 2026 NCT07724132
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
What is being tested: The combination of finerenone (a non-steroidal mineralocorticoid receptor antagonist) plus empagliflozin (an SGLT2 inhibitor) versus standard care in hospitalised heart…
23 Jul 2026 NCT06024746
● Recruiting Phase III Oncology
EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma
Trial testing whether adding immunotherapy (pembrolizumab) to standard glioblastoma treatment improves survival compared to standard treatment alone.
22 Jul 2026 NCT06556563
● Recruiting Phase III Gastroenterology
A Study of 36-Week Refill Exchanges of Port Delivery System (PDS) With Ranibizumab in nAMD
Trial testing a surgically implanted eye device that delivers ranibizumab every 36 weeks for age-related macular degeneration.
22 Jul 2026 NCT06847542
active not recruiting Phase III Oncology
Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy for HR+/HER2- Locally Recurrent Inoperable or Metastatic Breast Cancer (MK-3475-B49/KEYNOTE-B49)
Pembrolizumab added to chemotherapy versus chemotherapy alone for advanced hormone receptor-positive breast cancer, with PFS as primary endpoint in PD-L1 positive patients.
22 Jul 2026 NCT04895358
● Recruiting Phase III Diabetes / Metabolic
Efficacy and Safety of Ribupatide Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes
What is being tested: Ribupatide (KAI-9531), a novel once-weekly subcutaneous injection, is being evaluated for weight reduction in people with obesity without diabetes, compared…
22 Jul 2026 NCT07284979
● Recruiting Phase III Oncology
DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer (epNEC) to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy
What is being tested: Obrixtamig (a DLL3-targeting therapy) combined with carboplatin and etoposide chemotherapy versus standard chemotherapy alone in patients with advanced extrapulmonary neuroendocrine…
22 Jul 2026 NCT07544654
● Recruiting Phase III
A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of GM1 Gangliosidosis or GM2 Gangliosidosis
Oral nizubaglustat tested against placebo over 18 months in children with late-infantile or juvenile GM1/GM2 gangliosidosis.
21 Jul 2026 NCT07082543
active not recruiting Phase III Oncology
A Clinical Study of Pembrolizumab (+) Berahyaluronidase Alfa (MK-3475A) to Treat Newly-diagnosed Metastatic Non-small Cell Lung Cancer (MK-3475A-F84)
Trial comparing subcutaneous versus intravenous pembrolizumab delivery for newly-diagnosed metastatic non-small cell lung cancer.
21 Jul 2026 NCT06698042
● Recruiting Phase III
A Study to Assess Efficacy and Safety of Empasiprubart Versus IVIg in Adults With CIDP
Trial comparing new drug empasiprubart against standard IVIg treatment for CIDP over 24 weeks, then all patients receive empasiprubart for 24 months.
21 Jul 2026 NCT06920004
active not recruiting Phase III Rheumatology
A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With ISN/RPS 2003 Class III or IV Lupus Nephritis
A drug called obinutuzumab added to standard lupus kidney treatment improved kidney function and was safe compared to placebo.
21 Jul 2026 NCT04221477
● Recruiting Phase III Respiratory / COPD / Asthma
Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen
Treatment being tested: Tozorakimab (a monoclonal antibody) administered as an add-on to standard care in hospitalised patients with viral lung infection requiring supplemental oxygen,…
21 Jul 2026 NCT05624450
● Recruiting Phase III Oncology
AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian Cancer
What is being tested: AZD5335 (a folate receptor alpha inhibitor) is compared against mirvetuximab soravtansine in FRα-high tumours and against chemotherapy in FRα-low tumours,…
21 Jul 2026 NCT07218809
active not recruiting Phase III
24 Weeks Double-blind Randomized Placebo-controlled Trial to Evaluate Efficacy, PK, Safety of LOU064 in Adolescents (12 – <18) With CSU and Inadequate Response to H1-antihistamine Followed by Optional 3 Years Open-label Extension and an Optional 3 Years Safety Long-term Treatment-free Follow-up
Remibrutinib versus placebo for adolescent chronic urticaria inadequately controlled by antihistamines, with long-term safety follow-up.
20 Jul 2026 NCT05677451
● Recruiting Phase III Oncology
A Clinical Study of Belzutifan (MK-6482) and Zanzalintinib in People With Renal Cell Carcinoma (RCC) (LITESPARK-034/LS-034/MK-6482-034)
What is being tested: The trial evaluates belzutifan (MK-6482), a targeted therapy already used for RCC, combined with zanzalintinib (a new investigational agent) to…
20 Jul 2026 NCT07489495
● Recruiting Phase III Respiratory / COPD / Asthma
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-2)
GB-0895 is being tested as an add-on therapy for adolescents and adults with severe asthma that remains uncontrolled despite treatment with inhaled corticosteroids and…
20 Jul 2026 NCT07359846
active not recruiting Phase III Oncology
Study of XL092 + Atezolizumab vs Regorafenib in Participants With Metastatic Colorectal Cancer
New drug combination XL092 plus atezolizumab compared to regorafenib for advanced bowel cancer that hasn't responded to standard treatment.
17 Jul 2026 NCT05425940
active not recruiting Phase III
A Study to Investigate the Efficacy and Safety of Brepocitinib in Adults With Dermatomyositis
Brepocitinib, a new immune-suppressing drug, tested against placebo in adults with dermatomyositis over 52 weeks.
17 Jul 2026 NCT05437263
active not recruiting Phase III
A Study to Assess Safety, Tolerability and Efficacy of Garetosmab Versus Placebo Administered Intravenously (IV) in Adult Participants With Fibrodysplasia Ossificans Progressiva (FOP)
Garetosmab injection tested against placebo in adults with FOP to assess safety and effectiveness at slowing bone formation.
17 Jul 2026 NCT05394116
● Recruiting Phase III
An Efficacy and Safety Study of Cenegermin Ophthalmic Solution Compared With Vehicle in the Treatment of PCED
Cenegermin eye drops versus placebo for treating persistent corneal erosion, measuring complete healing at four weeks.
16 Jul 2026 NCT07519902
active not recruiting Phase III Oncology
A Study of Zolbetuximab (IMAB362) Plus CAPOX Compared With Placebo Plus CAPOX as First-line Treatment of Subjects With Claudin (CLDN) 18.2-positive, HER2-negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (GLOW).
Zolbetuximab plus chemotherapy versus placebo plus chemotherapy for first-line treatment of advanced gastric or gastroesophageal junction cancer positive for Claudin 18.2.
16 Jul 2026 NCT03653507
● Recruiting Phase III Oncology
A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy
What is being tested: Oral upadacitinib (a JAK inhibitor) is being evaluated for safety and efficacy in treating moderate to severe hidradenitis suppurativa in…
16 Jul 2026 NCT05889182
active not recruiting Phase III Neurology
A Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison With Fingolimod in Children and Adolescents With Relapsing-remitting Multiple Sclerosis (RRMS)
Ocrelizumab versus fingolimod for treating multiple sclerosis in children and teenagers over 24 weeks.
15 Jul 2026 NCT05123703
● Recruiting Phase III Oncology
VO and Nivolumab vs Physician’s Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]
IGNYTE-3 Trial Summary VO plus nivolumab versus standard treatment for melanoma that progressed after checkpoint inhibitor therapy.
15 Jul 2026 NCT06264180
● Recruiting Phase III Respiratory / COPD / Asthma
A Study to See if Tolvaptan is Safe in Infants and Children Who at Enrollment Are 28 Days to Less Than 18 Years Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)
What is being tested: Tolvaptan (a vasopressin V2-receptor antagonist) is being evaluated for safety and pharmacodynamic effects in infants and children aged 28 days…
15 Jul 2026 NCT04782258
● Recruiting Phase III Diabetes / Metabolic
Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes
What is being tested: Ribupatide (KAI-9531), a once-weekly subcutaneous injection, is being evaluated for its efficacy in reducing body weight and improving glycaemic control…
15 Jul 2026 NCT07284901
● Recruiting Phase III Diabetes / Metabolic
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin
Being tested: Elecoglipron (a novel therapeutic agent) versus placebo in patients with type 2 diabetes who have impaired renal function, all receiving background dapagliflozin…
15 Jul 2026 NCT07662135