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Clinical Trial ● Currently Recruiting Phase III NCT07223593

Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease

Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease — Recruiting • Phase III • Cardiology / Cardiovascular • NCT07223593.

📅 17 Apr 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Phase III
NCT ID
NCT07223593
Sponsor
Eli Lilly and Company
Start
2025-10-31
ClinicaliQ Trial Snapshot
  • Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease — Recruiting • Phase III • Cardiology / Cardiovascular • NCT07223593.
  • What is being tested: Orforglipron, a once-daily treatment, is being evaluated for its efficacy and safety in managing Fontaine II peripheral arterial disease (symptomatic claudication with reproducible symptoms on exercise).
  • Patient eligibility overview: The trial enrolls participants with confirmed Fontaine II PAD, which represents the symptomatic claudication stage of peripheral artery disease; specific inclusion/exclusion criteria would determine cardiovascular risk profile and disease severity requirements.
Use This Page For
  • Quick orientation before opening the registry record.
  • Checking recruitment status, phase and sponsor at a glance.
  • Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying

The purpose of this study is to evaluate the effect and safety of orforglipron once daily in participants with Fontaine II peripheral arterial disease (PAD). Participation in the study will last about 58 weeks.

Eligibility Snapshot
  • : * Have symptomatic PAD with intermittent claudication of Fontaine Stage II * Have an Ankle Brachial Index (ABI) of 0.9 or less

Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
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