ClinicaliQ Trial Snapshot
- A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients — Recruiting • Phase III • Cardiology / Cardiovascular • NCT06008197.
- What is being tested: Finerenone (a non-steroidal mineralocorticoid receptor antagonist) versus placebo in hospitalized patients with acute decompensated heart failure, specifically targeting those with mildly reduced or preserved ejection fraction (HFmrEF/HFpEF).
- Patient eligibility overview: The trial enrolls patients currently hospitalized with acute decompensated heart failure who have left ventricular ejection fraction in the mildly reduced or preserved range, representing a population historically underrepresented in heart failure therapeutic trials.
Use This Page For
- Quick orientation before opening the registry record.
- Checking recruitment status, phase and sponsor at a glance.
- Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying
Finerenone will be compared to placebo to determine efficacy and safety of treatment in patients hospitalized with acute decompensated heart failure (HF) and mildly reduced or preserved left ventricular ejection fraction.
Eligibility Snapshot
- : * Provide written informed consent * Age ≥18 years or legal age of majority if >18 years in the participant's country of residence * Current hospitalization or recently discharged (during or within 30 days of discharge) with the primary diagnosis of heart failure * Heart failure signs and symptoms at the time of hospital admission * Imaging evidence of mildly reduced or preserved left ventricular ejection fraction (EF) (40% or higher) * Elevated N-terminal pro B-type natriuretic peptide (NTproBNP) ≥500 pg/mL or B-type natriuretic peptide (BNP) ≥125 pg/mL for patients without atrial fibrillation (AF); or elevated NTproBNP ≥1500 pg/mL or BNP ≥375 pg/mL for patients with AF
Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.