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Clinical Trial Active — Not Recruiting Phase I NCT05249426

A Study to Test Whether Different Combinations of BI 765063, Ezabenlimab, Chemotherapy, Cetuximab, and BI 836880 Help People With Head and Neck Cancer or Liver Cancer

A Study to Test Whether Different Combinations of BI 765063, Ezabenlimab, Chemotherapy, Cetuximab, and BI 836880 Help People With Head and Neck Cancer or Liver Cancer — Active…

📅 28 Apr 2026 ⏱ 2 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Phase I
NCT ID
NCT05249426
Start
2022-04-12
Completion
2024-07-15
ClinicaliQ Trial Snapshot
  • A Study to Test Whether Different Combinations of BI 765063, Ezabenlimab, Chemotherapy, Cetuximab, and BI 836880 Help People With Head and Neck Cancer or Liver Cancer — Active Not Recruiting • Phase I • Oncology • NCT05249426.
  • Trial testing immune-boosting antibodies plus cetuximab for advanced head and neck cancer patients who've failed standard treatment.

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What This Trial Is Studying

With an amendment of the protocol, this study is only open to adults with head and neck cancer. Previously also adults with liver cancer joined. This is a study for people for whom previous treatment was not successful or no standard treatment exists. The purpose of this study is to find out whether combining different medicines make tumours shrink. The tested medicines in this study are antibodies that act in different ways against cancer. BI 765063 and ezabenlimab may help the immune system fight cancer (checkpoint inhibitors). Cetuximab blocks growth…

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
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