ClinicaliQ Trial Snapshot
- OPM- MEG in Non-immune And iMmune-medIated Neurological Disease — Recruiting • Non-phase study • Respiratory / COPD / Asthma • NCT07689682.
- What is being tested: Optically Pumped Magnetometer (OPM)-MEG brain imaging technology to detect abnormal neural activity patterns in patients with immune-mediated neurological diseases (autoimmune encephalitis, ADEM, multiple sclerosis) and non-immune neurological conditions, aiming to identify biomarkers that current diagnostic methods miss.
- Patient eligibility overview: The trial recruits patients with confirmed or suspected autoimmune and immune-mediated neurological disorders, alongside control groups with non-immune neurological diseases, enabling comparative analysis of brain activity signatures across disease categories.
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- Quick orientation before opening the registry record.
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What This Trial Is Studying
Over the past 20 years, doctors have gotten much better at spotting and treating brain conditions caused by the immune system attacking the body. These include illnesses like autoimmune encephalitis, ADEM, and multiple sclerosis. But even with better treatments, many patients-especially children-still struggle with long-term problems. Standard brain scans and tests often miss important issues like memory problems, emotional difficulties, trouble sleeping, and challenges with social behaviour. Early research using a special brain imaging technique (called MEG) has shown changes in brain networks that seem to be linked to poor…
Eligibility Snapshot
- : * Individuals (age range 2 yrs to 16 years) who have received a diagnosis of immune-mediated neurological disease e.g. autoimmune encephalitis1, acute disseminated encephalomyelitis, multiple sclerosis. 2 * Individuals who have received a diagnosis of a non-immune mediated neurological disease (age range 2 yrs to 15 years 11 months) e.g. stroke. * Patients who can give informed consent/ assent and have a person with parental responsibility capable of giving informed consent on their behalf if aged
Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.