- Study of ALXN2220 Versus Placebo in Adults With ATTR-CM — Active Not Recruiting • Phase III • Cardiology / Cardiovascular • NCT06183931.
- ALXN2220 drug tested against placebo in adults with heart amyloidosis, measuring death and heart-related events.
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The primary objective of this study is to access the efficacy of ALXN2220 in the treatment of adult participants with ATTR-CM by evaluating the difference between the ALXN2220 and placebo groups as assessed by the total occurrences of all-cause mortality (ACM) and cardiovascular (CV) clinical events. Conditions: Transthyretin Amyloid Cardiomyopathy Interventions: ALXN2220, Placebo Lead Sponsor: Alexion Pharmaceuticals, Inc. Planned Enrollment: 1182 participants