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Clinical Trial Active — Not Recruiting Phase III NCT06183931

Study of ALXN2220 Versus Placebo in Adults With ATTR-CM

Study of ALXN2220 Versus Placebo in Adults With ATTR-CM — Active Not Recruiting • Phase III • Cardiology / Cardiovascular • NCT06183931.

📅 22 Oct 2026 ⏱ 1 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Phase III
NCT ID
NCT06183931
Start
2024-01-11
Completion
2027-12-06
ClinicaliQ Trial Snapshot
  • Study of ALXN2220 Versus Placebo in Adults With ATTR-CM — Active Not Recruiting • Phase III • Cardiology / Cardiovascular • NCT06183931.
  • ALXN2220 drug tested against placebo in adults with heart amyloidosis, measuring death and heart-related events.

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What This Trial Is Studying

The primary objective of this study is to access the efficacy of ALXN2220 in the treatment of adult participants with ATTR-CM by evaluating the difference between the ALXN2220 and placebo groups as assessed by the total occurrences of all-cause mortality (ACM) and cardiovascular (CV) clinical events. Conditions: Transthyretin Amyloid Cardiomyopathy Interventions: ALXN2220, Placebo Lead Sponsor: Alexion Pharmaceuticals, Inc. Planned Enrollment: 1182 participants

Full Trial Details
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Eligibility criteria, protocol, and results when available
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