Register Free
Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Women's Health Rheumatology Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

2231 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

2231 recruiting AI clinical summaries
Explore Trial Collections Follow research updates
All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
🔬
Trial Radar

Clinical Trial Intelligence

● Recruiting Phase II Rheumatology
A Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Systemic Juvenile Idiopathic Arthritis (SKYPS)
SKYPS Trial Summary Sarilumab dose-finding study in children with systemic juvenile idiopathic arthritis to establish safe, effective dosing and assess safety outcomes.
19 Oct 2026 NCT02991469
● Recruiting Oncology
A Study to Learn How Men With Advanced Prostate Cancer Respond to Treatment With Darolutamide and Hormone Therapy, With or Without Chemotherapy, in Real-world Medical Practice
This is an international, prospective, open-label, multicenter, multi-cohort, non-interventional observational study designed to describe the real-world effectiveness and safety of darolutamide in combination with…
19 Oct 2026 NCT07344779
● Recruiting Phase II Oncology
Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Breast Cancer w/Liver Dominant Disease
The goal of this clinical trial is to learn if using a liver-directed therapy with high dose chemotherapy followed by approved cancer treatment to…
19 Oct 2026 NCT06875128
● Recruiting Phase I
Phase 1/2 Study of ABO-101 in Primary Hyperoxaluria Type 1 (redePHine)
The goal of the redePHine study is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of ABO-101 in participants with primary hyperoxaluria type 1…
19 Oct 2026 NCT06839235
● Recruiting Phase III Infectious Disease
An Open Label Clinical Study to Evaluate Tanruprubart (Also Commonly Known as ANX005) in Participants With Guillain-Barré Syndrome (FORWARD Study)
The goal of this open label study is to measure pharmacokinetics, pharmacodynamics, early efficacy, and safety of tanruprubart in adult and pediatric participants, in…
19 Oct 2026 NCT07020819
● Recruiting Phase I Respiratory / COPD / Asthma
A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD
The purpose of this open-label study is to assess the safety, tolerability, pharmacodynamics, and pharmacokinetics of WVE-006 in participants with alpha-1 antitrypsin deficiency (AATD)…
19 Oct 2026 NCT06405633
● Recruiting Phase III Diabetes / Metabolic
A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes
This study looks at how well a medicine called orforglipron works compared to another medicine called dulaglutide in pediatric participants aged 10 to less…
19 Oct 2026 NCT07668336
● Recruiting Diabetes / Metabolic
A Multi-centre Trial to Assess the Efficacy and Safety of the Omnipod 5 System in People With Type 2 Diabetes Undergoing Haemodialysis
Diabetes is the leading cause of kidney failure in the UK. Many people with diabetes and advanced kidney failure inject themselves with insulin and…
19 Oct 2026 NCT07422532
● Recruiting Phase I Oncology
Study of ART6043 in Advanced/Metastatic Solid Tumors Patients (POLKA)
This interventional study will evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of ART6043 as monotherapy or in combination with olaparib.
19 Oct 2026 NCT05898399
● Recruiting Phase IV Oncology
The FLOTILLA Study: Providing Continued Access to The Study Medicines Encorafenib and Binimetinib for Participants in Prior Clinical Trials
The purpose of this clinical trial (called the FLOTILLA study) is to give continued access to the study medicines, as well as safety follow-up,…
19 Oct 2026 NCT05203172
● Recruiting
Genetics of Charcot Marie Tooth (CMT) – Modifiers of CMT1A, New Causes of CMT2
Research identifying new CMT-causing genes and genes that modify disease severity in CMT patients.
16 Oct 2026 NCT01193088
active not recruiting Cardiology / Cardiovascular
Breathing-Maneuver-Induced Myocardial Oxygenation Reserve Validated by FFR (B-MORE)
Study tested whether a breathing technique can help identify heart muscle oxygen problems in patients with possible blocked coronary arteries.
16 Oct 2026 NCT04126148
active not recruiting Cardiology / Cardiovascular
Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion
Occlutech Flex II PFO occluder shows non-inferiority to standard devices for closing heart defects and preventing recurrent stroke.
16 Oct 2026 NCT05069558
active not recruiting
REDUCER-I: An Observational Study of the Neovasc Reducer™ System
A study tracking long-term outcomes of a device that reduces pressure in coronary veins to relieve chest pain in patients not helped by standard…
16 Oct 2026 NCT02710435
● Recruiting
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others
Study tracking how different types of inherited nerve disease progress over five years and testing new measurement tools.
16 Oct 2026 NCT01193075
● Recruiting Phase III Rheumatology
A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
This is a multicenter, randomized, double-blind, placebo-controlled Phase 3 maintenance study to evaluate the efficacy and safety of duvakitug in participants with moderately to…
16 Oct 2026 NCT07185009
● Recruiting Phase II Respiratory / COPD / Asthma
A Study to Find an Efficacious and Safe Dose of CHF10067 (Zampilimab) in Participants With Idiopathic Pulmonary Fibrosis
The purpose of this study is to evaluate the efficacy, safety, and tolerability at Week 24 of 2 doses of CHF10067 (zampilimab) in participants…
16 Oct 2026 NCT07516951
● Recruiting Oncology
PRophylactic Cerebral Irradiation or Active MAgnetic Resonance Imaging Surveillance in Small-cell Lung Cancer Patients (PRIMALung Study)
In this phase III study, the primary objective is to test with a one-sided significance of 5% whether for the treatment of small cell…
16 Oct 2026 NCT04790253
● Recruiting Cardiology / Cardiovascular
HCMR Re-Imaging Study
This study aims to learn what might predict heart problems (like sudden death from a fast heart rhythm or heart failure) in people with…
16 Oct 2026 NCT07054073
● Recruiting Phase II Oncology
A Study to Assess the Effectiveness and Safety of Pacritinib in Patients With VEXAS Syndrome (PAXIS)
This trial is to assess the effectiveness and safety of pacritinib in patients with VEXAS (i.e., Vacuoles in myeloid progenitors, E1 ubiquitin-activating enzyme, X-linked,…
16 Oct 2026 NCT06782373
active not recruiting Phase III
A Study to Investigate Efficacy, Safety, and Tolerability of Remibrutinib Compared With Placebo in Adults With CINDU Inadequately Controlled by H1-antihistamines
Remibrutinib reduces itch and hives in chronic urticaria patients not controlled by antihistamines over 52 weeks.
15 Oct 2026 NCT05976243
● Recruiting Phase III
A Study to Evaluate the Efficacy of NIO752 in Participants With Progressive Supranuclear Palsy
NIO752 is being tested to see if it can help slow progression of Progressive Supranuclear Palsy, a rare brain disorder affecting movement and balance.
15 Oct 2026 NCT07498426
active not recruiting Phase III Oncology
A Study of Sasanlimab in People With Non-muscle Invasive Bladder Cancer
Trial testing sasanlimab combined with BCG treatment for early-stage bladder cancer to assess safety and effectiveness.
15 Oct 2026 NCT04165317
● Recruiting Respiratory / COPD / Asthma
A Study to Understand the Accuracy of a New Breathing Device Compared to Standard Testing for Asthma and COPD
The diagnosis of either asthma or chronic obstructive pulmonary disease (COPD) is currently based on a combination of symptoms, different lung tests and sometimes…
15 Oct 2026 NCT07253883
● Recruiting Phase III Oncology
Saruparib in Combination With Physician’s Choice of ARPI in Patients With mHSPC Previously Treated With Docetaxel or 177Lu-PSMA Therapy Without Disease Progression and PSA ≥ 0.2 ng/mL (EvoPAR-PR05)
The primary objective of this study is to measure efficacy of saruparib + physician's choice of ARPI compared with placebo + ARPI in men…
15 Oct 2026 NCT07711002
● Recruiting Respiratory / COPD / Asthma
Urine Collection and Novel UTI Biomarkers in Children and Older Adults
Suspected urinary tract infection (UTI) is a common driver of antibiotic prescribing and hospital admission, yet accurate diagnosis remains challenging. Young children and older…
15 Oct 2026 NCT07766278
● Recruiting Phase II Respiratory / COPD / Asthma
AURA-IPF: A Randomized Phase 2 Study to Evaluate the Safety and Efficacy of AP02 (Nintedanib Solution) in IPF
This study will evaluate the impact Nintedanib Solution for Inhalation (AP02) has on lung function and key measures of fibrosis in adult patients with…
15 Oct 2026 NCT07194382
● Recruiting Phase II Cardiology / Cardiovascular
Dose-finding Study of YMI024 to Assess Efficacy, Safety, and Tolerability in Adults With Stable Coronary Artery Disease and Elevated hsCRP
The purpose of this Phase 2b study is to investigate the efficacy in reducing systemic inflammation, safety, tolerability, and dose response of five doses…
15 Oct 2026 NCT07830719
● Recruiting Phase II Cardiology / Cardiovascular
A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy
This study is open to adults with diabetic retinopathy. People who have non-proliferative diabetic retinopathy of moderate or high severity can join the study.…
15 Oct 2026 NCT06321302
● Recruiting Phase I Oncology
A Clinical Study of MK-4208/TERN-701 in Participants With Chronic Myeloid Leukemia (CML) (MK-4208-003/Tern701-1012/CARDINAL)
Researchers are looking for a new way to treat a blood cancer called chronic myeloid leukemia (CML). Researchers want to learn if MK-4208 (Tern-701)…
15 Oct 2026 NCT06163430
● Recruiting Phase III Rare Diseases
A Gaucher Disease Gene Therapy Trial With FLT201
Gene therapy FLT201 tested in Gaucher disease patients already on standard treatment, assessing whether it allows safe discontinuation of current medications.
14 Oct 2026 NCT07223944
active not recruiting Phase III Oncology
A Study Comparing Adjuvant Alectinib Versus Adjuvant Platinum-Based Chemotherapy in Patients With ALK Positive Non-Small Cell Lung Cancer
ALK-positive lung cancer patients randomly received either alectinib tablets for two years or chemotherapy for four months; alectinib improved recurrence-free survival.
14 Oct 2026 NCT03456076
● Recruiting Rare Diseases
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry
International registry tracking long-term outcomes and pregnancy complications in Gaucher disease patients receiving routine care.
14 Oct 2026 NCT00358943
active not recruiting Phase III Oncology
A Study of Dato-DXd With or Without Durvalumab Versus Investigator’s Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Without Pathological Complete Response Following Neoadjuvant Therapy (TROPION-Breast03)
TROPION-Breast03 Summary New cancer drug Dato-DXd, with or without immunotherapy, tested against standard treatment in triple-negative breast cancer patients with remaining disease after chemotherapy.
14 Oct 2026 NCT05629585
active not recruiting
Episealer® Knee System IDE Clinical Study
Episealer Knee System treats painful knee cartilage damage in a randomised controlled trial comparing its effectiveness against standard treatment.
14 Oct 2026 NCT04000659
● Recruiting Phase III Rheumatology
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn’s Disease
The purpose of this study is to assess how well JNJ-78934804 works (efficacy) and how safe it is (safety) as compared to guselkumab at…
14 Oct 2026 NCT07577843
● Recruiting Phase II Mental Health / Psychiatry
ALTO-100 in Bipolar Disorder With Depression (BD-D)
ALTO-100 tested against placebo for treating depression in bipolar disorder patients already on mood stabilizers or antipsychotics.
13 Oct 2026 NCT06656416
active not recruiting
F15 Recharge Free Axonics SNM System Clinical Study
A study testing the Axonics wireless nerve stimulator for overactive bladder and bowel incontinence, which doesn't need recharging.
13 Oct 2026 NCT06186765
● Recruiting Phase III
Lisaftoclax (APG-2575) Combined With Azacytidine (AZA) in the Treatment of Patients With Higher-risk Myelodysplastic Syndrome (GLORA-4).
GLORA-4 Trial Summary Adding lisaftoclax to azacitidine improves survival in newly diagnosed high-risk myelodysplastic syndrome compared to azacitidine alone.
13 Oct 2026 NCT06641414
● Recruiting Phase II / Phase III Gastroenterology
A Clinical Study to Assess Safety, Efficacy and Pharmacodynamic Profile of GNT0004 in Duchenne Muscular Dystrophy
GNT0004 is a one-time gene therapy delivering a functional dystrophin gene to slow Duchenne muscular dystrophy progression.
13 Oct 2026 NCT07856329
● Recruiting
Axonics R20 Post-Market Clinical Follow-up (PMCF) Study for the Indication of Fecal Incontinence
A study tracking how well Axonics rechargeable nerve stimulators work for bowel incontinence in routine clinical practice.
13 Oct 2026 NCT07499258
● Recruiting Phase I Respiratory / COPD / Asthma
Evaluation of Safety, Side Effects, and How the Drug, Inhaled CHF10136, Is Absorbed, Modified and Removed From the Body in Healthy Adults and Adults With Asthma
This study evaluates the safety and tolerability of CHF10136 administered by inhalation in healthy adults and adults with asthma. The study includes single-dose, multiple-dose,…
13 Oct 2026 NCT07851623
● Recruiting Phase III Cardiology / Cardiovascular
Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma
The purpose of this study is to assess the efficacy and safety of cevostamab in combination with pomalidomide and dexamethasone (CevosPd) versus standard of…
13 Oct 2026 NCT07555938
● Recruiting Cardiology / Cardiovascular
Balloon vs. Self Expanding Transcatheter Valve for Degenerated Bioprosthesis
Transcatheter aortic valve implantation (TAVI) serves a growing spectrum of patients with symptomatic severe aortic stenosis (AS). Approximately 80% of surgical aortic valve replacements…
13 Oct 2026 NCT04843072
● Recruiting Phase I Oncology
AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia
This is a Phase 1/2, global multicentre, open-label, single-arm, dose escalation and dose optimization study of surovatamig (AZD0486) to evaluate the safety, tolerability, and…
13 Oct 2026 NCT06137118
active not recruiting Phase II Gastroenterology
Study to Evaluate the Efficacy, Safety and Tolerability of MAS825 in Patients With Monogenic IL-18 Driven Autoinflammatory Diseases, Including NLRC4-GOF, XIAP Deficiency, or CDC42 Mutations
MAS825 tested as treatment for rare genetic inflammatory disorders caused by NLRC4, XIAP, or CDC42 mutations.
09 Oct 2026 NCT04641442
active not recruiting Phase III
A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy
Long-term study showing VX-121 combination therapy is safe and effective for treating cystic fibrosis patients.
09 Oct 2026 NCT05444257
active not recruiting
Merit WRAPSODY™ Endoprosthesis for Treatment of Stenosis or Occlusion (WRAP)
WRAP Study Summary Real-world trial testing whether the WRAPSODY stent safely and effectively treats blocked or narrowed blood vessels in patients.
09 Oct 2026 NCT05062291
● Recruiting Dermatology
Exploratory Study of Peristomal and Non-Peristomal Skin Barrier Characteristics in People With a Stoma
Study comparing skin health around stomas versus normal skin, and differences between colostomy, ileostomy, and urostomy types.
09 Oct 2026 NCT07719309
● Recruiting Neurology
Wearable for Assessing Tremor and Continuous Health in Parkinson’s Disease and Essential Tremor
What is being tested: Non-invasive wearable sensors are being evaluated to measure tremor and upper-limb movement patterns in adults with Parkinson's disease or essential…
09 Oct 2026 NCT07787299