Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Women's Health Rheumatology Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Clinical Trial Active — Not Recruiting Phase III NCT05444257

A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy

A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy — Active Not Recruiting • Phase III • NCT05444257.

📅 09 Oct 2026 ⏱ 1 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Phase III
NCT ID
NCT05444257
Start
2022-11-08
Completion
2026-10-30
ClinicaliQ Trial Snapshot
  • A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy — Active Not Recruiting • Phase III • NCT05444257.
  • Long-term study showing VX-121 combination therapy is safe and effective for treating cystic fibrosis patients.

Verify eligibility, endpoints and current status on the original ClinicalTrials.gov registry before acting on this summary.

Use This Page For
  • Quick orientation before opening the registry record.
  • Checking recruitment status, phase and sponsor at a glance.
  • Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying

The purpose of this study is to evaluate the long-term safety, tolerability, and efficacy of VX-121/tezacaftor/deutivacaftor (VX-121/TEZ/D-IVA) in participants with cystic fibrosis. Conditions: Cystic Fibrosis Interventions: VX-121/TEZ/D-IVA Lead Sponsor: Vertex Pharmaceuticals Incorporated Planned Enrollment: 822 participants

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
View Trial ↗
Share: Twitter/X LinkedIn