Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Women's Health Rheumatology Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

2231 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

2231 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase II Oncology
Alpelisib in Pediatric and Adult Patients With Lymphatic Malformations Associated With a PIK3CA Mutation.
What is being tested: Alpelisib (a PI3K inhibitor) administered as film-coated tablets in pediatric and adult patients with lymphatic malformations (LyM) caused by PIK3CA…
09 Oct 2026 NCT05948943
● Recruiting Phase I Oncology
Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors
Drug being tested: XmAb541, an investigational immunotherapy agent, is undergoing Phase 1 evaluation to establish safety, tolerability, and optimal dosing in patients with advanced…
09 Oct 2026 NCT06276491
● Recruiting Phase III Oncology
Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)
Treatment being tested: Gedatolisib (a PI3K/mTOR inhibitor) combined with palbociclib (CDK4/6 inhibitor) and endocrine therapy, compared to standard palbociclib plus endocrine therapy in first-line…
09 Oct 2026 NCT06757634
● Recruiting Phase III Oncology
A Clinical Trial of Calderasib (MK-1084) and Durvalumab in People With Non-Small Cell Lung Cancer (MK-1084-015/KANDLELIT-015)
What is being tested: The combination of calderasib (MK-1084), a KRAS G12C inhibitor, with durvalumab (an immunotherapy) in patients with locally advanced, unresected non-small…
09 Oct 2026 NCT07554339
● Recruiting Phase III Gastroenterology
A Study to Compare Linvoseltamab Monotherapy and Linvoseltamab + Carfilzomib Combination Therapy With Standard-of-Care Combination Regimens in Adult Participants With Relapsed/Refractory Multiple Myeloma (RRMM)
Trial testing linvoseltamab alone or with carfilzomib versus standard treatments in patients with relapsed/refractory myeloma after 1-3 prior therapies.
08 Oct 2026 NCT07222761
active not recruiting
Enlighten Study: The EV-ICD Post Approval Registry
Post-market study tracking safety and effectiveness of Medtronic's subcutaneous implantable defibrillator in routine NHS practice.
08 Oct 2026 NCT06048731
● Recruiting Oncology
BEAT-Breast: Trial of DE-iPTV in Patients With Primary Breast Cancer With Brain Metastases Who Are Not Suitable for Stereotactic Radiotherapy.
What is being tested: DE-iPTV (Dose Escalated internal Planning Target Volume), a novel modern radiotherapy technique designed to deliver optimized radiation therapy to patients…
08 Oct 2026 NCT06611306
● Recruiting Cardiology / Cardiovascular
A Study to Learn About the Use of Acoramidis in Patients With a Heart Condition Called Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in a Real-world Setting
Treatment being tested: Acoramidis, a transthyretin stabiliser designed to prevent misfolding and accumulation of amyloid fibrils in the heart muscle of patients with ATTR-CM.…
08 Oct 2026 NCT07235462
● Recruiting Cardiology / Cardiovascular
Dynamic Voltage Mapping to Personalise the Ventricular Tachycardia Substrate
Testing personalised VT ablation using dynamic voltage mapping – This trial evaluates whether real-time electrical mapping during procedures can identify patient-specific scar tissue patterns…
08 Oct 2026 NCT07573579
● Recruiting Cardiology / Cardiovascular
Prospective Evaluation of AI-ECG for SHD Detection
What is being tested: An artificial intelligence-enhanced electrocardiography (AI-ECG) system's diagnostic accuracy for detecting structural heart disease in adults, compared against standard 12-lead ECG,…
08 Oct 2026 NCT07057466
● Recruiting Phase I Oncology
A Study of CHM-029 in Participants With NPM1 Mutated, KMT2A or NUP98 Rearranged AML
What is being tested: CHM-029, an investigational oral medication, is being evaluated for safety and efficacy in adult patients with specific subtypes of acute…
08 Oct 2026 NCT07751991
active not recruiting Oncology
Follow-up in Gynecological Cancer Survivors
Gynecological cancer patients were studied to understand their follow-up care patterns and outcomes after initial treatment.
07 Oct 2026 NCT03515993
● Recruiting
Satiety, Microbiome, Appetite Regulation, and Tracking Energy Across Targeted Snacks: Acute Postprandial Study
Study tests whether a special snack bar reduces hunger, overall food intake, and improves mood and energy in healthy adults over five days.
07 Oct 2026 NCT07776418
● Recruiting Phase III
Pridopidine Phase 3 Study in Huntington’s Disease
Pridopidine versus placebo over one year to assess whether the drug slows Huntington's Disease progression and worsens symptoms.
07 Oct 2026 NCT07609108
● Recruiting Mental Health / Psychiatry
Testing the Efficacy of 100mg Vitamin-B6 Daily for Sensory Reactivity in Autism
High-dose vitamin B6 showed no significant benefit for reducing anxiety or sensory sensitivity in autistic adults compared to placebo.
07 Oct 2026 NCT06234501
● Recruiting Oncology
Identifying Immune Biomarkers of Disease and Disease Control in Autoimmune Neurological Disease Using Autologous Haematopoietic Stem Cell Transplantation
What is being tested: Identification of immune biomarkers that predict disease activity and treatment response in autoimmune neurological diseases (particularly MS) using autologous haematopoietic…
07 Oct 2026 NCT06195800
● Recruiting Cardiology / Cardiovascular
Predicting Plaque Growth Using Blood Flow Stress Markers: A Proof-of-Concept Study
What is being tested: Blood flow stress markers (biomechanical indicators) are being evaluated as predictive tools to identify which coronary artery plaques will progress…
07 Oct 2026 NCT07864051
● Recruiting Cardiology / Cardiovascular
Identification of Lesion Characteristics in Coronary Plaques Using Multimodality Intravascular Imaging and Novel Photon-counting CT in Stable Angina
What is being tested: A novel combination of multimodality intravascular imaging and advanced photon-counting CT technology to characterize and identify high-risk coronary plaque lesions…
07 Oct 2026 NCT07864025
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Compare Linvoseltamab and Daratumumab Treatment in High-Risk Smoldering Multiple Myeloma (HR-SMM)
Treatment being tested: Linvoseltamab (an experimental bispecific antibody) is being compared to daratumumab (an established monoclonal antibody) in patients with high-risk smoldering multiple myeloma…
07 Oct 2026 NCT07393282
● Recruiting
The United Kingdom National Registry for Myotonic Dystrophy
UK registry tracking myotonic dystrophy patients to improve understanding and identify future clinical trial participants.
06 Oct 2026 NCT04003363
active not recruiting Phase II / Phase III
Setrusumab vs Placebo for Osteogenesis Imperfecta
Setrusumab (an antibody) reduces fractures in osteogenesis imperfecta patients compared to placebo.
06 Oct 2026 NCT05125809
● Recruiting Cardiology / Cardiovascular
Study of Hospitalised Patients With Acute Respiratory Conditions
What is being tested: This observational study evaluates short- and long-term outcomes in hospitalised patients with acute respiratory conditions, including acute exacerbations of chronic…
06 Oct 2026 NCT05095090
● Recruiting Phase I Oncology
A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Patients With Bladder Cancer (MK-2870-027)
Drug being tested: Sacituzumab Tirumotecan (MK-2870), an antibody-drug conjugate targeting Trop-2, administered directly into the bladder to determine safety, tolerability, and maximum tolerated dose…
06 Oct 2026 NCT06637423
● Recruiting
Application of the Maestro Surgical System for Surgical Assistance in Laparoscopic Abdominal Surgery
Study testing whether a robotic surgical system can safely assist surgeons during keyhole abdominal operations.
05 Oct 2026 NCT07858929
active not recruiting Phase III Cardiology / Cardiovascular
Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events
Inclisiran added to statins slows coronary artery plaque buildup in patients with mild coronary disease, measured by CT scans over two years.
05 Oct 2026 NCT05360446
● Recruiting Phase I
First-in-Human Dose-escalation of GSK4425689A: Safety, Tolerability, and PK in Healthy Adults
Early-stage trial testing a new antibody drug's safety and how the body processes it in healthy volunteers via injection or infusion.
05 Oct 2026 NCT07646353
active not recruiting Phase II Respiratory / COPD / Asthma
A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis
Inhaled pirfenidone added to standard care slowed lung decline in progressive pulmonary fibrosis patients over one year.
05 Oct 2026 NCT06329401
● Recruiting Phase III Diabetes / Metabolic
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)
What is being tested: Long-term efficacy, safety, and tolerability of maridebart cafraglutide, a novel dual-action GLP-1/GIP receptor agonist, in patients with concurrent obesity and…
05 Oct 2026 NCT07684144
● Recruiting Cardiology / Cardiovascular
Barts Revascularisation Registry
What is being tested: The registry evaluates minimally invasive interventional techniques for treating coronary artery disease, tracking real-world outcomes and safety data across different…
05 Oct 2026 NCT05255705
● Recruiting Cardiology / Cardiovascular
Developing Trustworthy Artificial Intelligence (AI)-Driven Tools to Predict Vascular Disease Risk and Progression
What is being tested: Development of AI algorithms designed to predict cardiovascular events and disease progression in abdominal aortic aneurysm (AAA) and peripheral arterial…
05 Oct 2026 NCT06206369
● Recruiting Phase III Oncology
Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
What is being tested: Atebimetinib (a MEK inhibitor) combined with modified gemcitabine-nab-paclitaxel (GnP) chemotherapy versus standard-of-care GnP alone as first-line treatment for metastatic pancreatic…
05 Oct 2026 NCT07562152
● Recruiting Phase II Oncology
A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Inebilizumab in Children With Generalized Myasthenia Gravis (gMG)
What is being tested: Inebilizumab, a monoclonal antibody targeting B cells, is being evaluated for its pharmacokinetics, pharmacodynamics, safety, and tolerability in children with…
05 Oct 2026 NCT06987539
● Recruiting Phase III Oncology
INTREPID: A Study of Sapablursen Evaluating the Safety and Efficacy in Participants With Polycythemia Vera (PV)
What is being tested: Sapablursen, an investigational antisense oligonucleotide, is being evaluated as an add-on therapy to standard of care treatment in patients with…
05 Oct 2026 NCT07429266
● Recruiting Neurology
Developing a New EEG Method for the Early Diagnosis of Dementia
Researchers are testing whether routine EEG scans with new analysis software can detect dementia earlier than current methods.
02 Oct 2026 NCT02426398
active not recruiting Phase III
A Phase III Study Evaluating Glofitamab in Combination With Gemcitabine + Oxaliplatin vs Rituximab in Combination With Gemcitabine + Oxaliplatin in Participants With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Glofitamab plus chemotherapy compared to rituximab plus chemotherapy for treating relapsed or refractory diffuse large B-cell lymphoma.
02 Oct 2026 NCT04408638
● Recruiting Phase III Rare Diseases
CAR-T Long Term Follow Up (LTFU) Study
Study tracking safety and effectiveness of CAR-T cancer therapy in patients for 15 years after treatment to detect delayed problems.
02 Oct 2026 NCT02445222
active not recruiting Cardiology / Cardiovascular
Effectiveness of the EMPOWER™ Modular Pacing System and EMBLEM™ Subcutaneous ICD to Communicate Antitachycardia Pacing
New modular pacemaker and implantable defibrillator system tested for safety and effectiveness in treating abnormal heart rhythms.
02 Oct 2026 NCT04798768
active not recruiting Cardiology / Cardiovascular
Future Innovations in Novel Detection for Atrial Fibrillation (FIND-AF): Pilot Study
This pilot study tests using computer-guided risk scoring and home ECG devices to identify and screen people at high risk of atrial fibrillation.
02 Oct 2026 NCT05898165
● Recruiting Mental Health / Psychiatry
Addressing Pregnant Women’s First Trimester Worries and Information Needs With mHealth Solutions
What is being tested: An mHealth (mobile health) solution designed to address pregnant women's anxieties and information needs during the first trimester (weeks 1-12…
02 Oct 2026 NCT07114471
● Recruiting Phase I Oncology
A Study of Mocertatug Rezetecan in Combination With Anti-cancer Therapies for Advanced Solid Tumors (BEHOLD-2)
What is being tested: Mocertatug rezetecan, a novel targeted cancer therapy, combined with existing anti-cancer treatments in patients with advanced solid tumors that have…
02 Oct 2026 NCT06796907
● Recruiting Phase III Oncology
A Study to Investigate Mocertatug Rezetecan Compared With Standard of Care in Participants With Platinum-resistant Ovarian Cancer (BEHOLD-Ovarian01)
What is being tested: Mocertatug rezetecan (Mo-Rez), a novel targeted therapy, is being compared against standard-of-care treatment in patients with platinum-resistant ovarian cancer, with…
02 Oct 2026 NCT07286266
● Recruiting Phase II
A Study of TYRA-300 in Children With Achondroplasia: BEACH301
TYRA-300 trial tests safety and effective doses of a new treatment for children with achondroplasia who still have growing bones.
01 Oct 2026 NCT06842355
● Recruiting Phase III Gastroenterology
A Study to Assess How Well and Safely Elafibranor Works in Adult Participants With Primary Sclerosing Cholangitis
Elafibranor versus placebo for primary sclerosing cholangitis: a trial assessing efficacy and safety in 350 adults over five years.
01 Oct 2026 NCT07387549
active not recruiting Phase III Neurology
Study to Evaluate the Efficacy, Safety and Tolerability of IMU-838 in Patients With Relapsing Multiple Sclerosis
IMU-838 reduced relapses in relapsing multiple sclerosis compared to placebo in this large randomised trial.
01 Oct 2026 NCT05201638
active not recruiting Phase II Gastroenterology
A Study to Assess Safety and Effectiveness of Elafibranor in Adult Participants With Primary Sclerosing Cholangitis.
A trial testing whether a drug called elafibranor can safely treat primary sclerosing cholangitis, a rare liver disease.
01 Oct 2026 NCT05627362
● Recruiting Cardiology / Cardiovascular
Patient Selection and Long-Term Outcomes of Pace & Ablate Strategy in Atrial Fibrillation
What is being tested: The pace-and-ablate strategy (atrioventricular node ablation with permanent pacing) in patients with drug-refractory or ablation-refractory atrial fibrillation, with particular focus…
01 Oct 2026 NCT07852221
● Recruiting Phase I Oncology
HTL0039732 in Participants With Advanced Solid Tumours
What is being tested: HTL0039732, a novel therapeutic agent, is being evaluated as monotherapy and in combination regimens with atezolizumab and other established anti-cancer…
01 Oct 2026 NCT05944237
● Recruiting Oncology
Innovative Ovarian Cancer Biomarker Assays
What is being tested: Blood-based biomarker assays designed to detect ovarian cancer earlier through analysis of circulating tumour markers and related biological indicators, offering…
01 Oct 2026 NCT07693894
● Recruiting Phase I Oncology
A Study Evaluating the Efficacy and Safety of Risvutatug Rezetecan in Participants With Advanced Sarcomas (EMBOLD Sarcoma-202)
Treatment being tested: Risvutatug Rezetecan (Ris-Rez), a novel therapeutic agent being evaluated for efficacy and safety in patients with advanced sarcomas, with assessment of…
01 Oct 2026 NCT07602777
● Recruiting
STRATA: Surgical Treatment Using Robotic Approach in The Acute Abdomen
STRATA Trial Summary Robotic surgery in emergency abdominal surgery improves outcomes and patient satisfaction compared to open or laparoscopic approaches.
30 Sep 2026 NCT07850401