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Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

1963 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

1963 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase III Rheumatology
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis
What is being tested: JNJ-78934804, a novel therapeutic agent, is being evaluated for efficacy and safety in treating moderately to severely active ulcerative colitis,…
28 Aug 2026 NCT07577856
● Recruiting Phase III Oncology
MK-3475A±Calderasib (MK-1084) in Completely Resected Stage IIA-IIIB (N2) KRAS G12Cm NSCLC (MK-1084-013)
What is being tested: Adjuvant calderasib (a KRAS G12C inhibitor) combined with pembrolizumab immunotherapy versus pembrolizumab alone in completely resected early-stage NSCLC with KRAS…
28 Aug 2026 NCT07431827
● Recruiting Cardiology / Cardiovascular
Longitudinal Study for Eosinophilic Granulomatosis With Polyangiitis
What is being tested: A longitudinal observational study collecting long-term clinical data on eosinophilic granulomatosis with polyangiitis (EGPA) to better understand disease progression, treatment…
28 Aug 2026 NCT00315380
● Recruiting Phase II Oncology
Testing Ivonescimab Versus FOLFOX in Advanced Biliary Tract Cancer Patients
What is being tested: Ivonescimab (a PD-L1/CTLA-4 bispecific antibody) is being compared against standard FOLFOX chemotherapy in patients with advanced biliary tract cancer who…
28 Aug 2026 NCT06529718
● Recruiting Phase I Oncology
A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer
What is being tested: Amivantamab (an EGFR/MET bispecific antibody) is being evaluated as monotherapy and in combination with pembrolizumab, paclitaxel, or pembrolizumab plus carboplatin…
28 Aug 2026 NCT06385080
● Recruiting Phase III Oncology
A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer
What is being tested: TAR-210 (a novel intravesical therapeutic) is being compared against standard single-agent intravesical chemotherapy to evaluate which approach better prevents recurrence…
28 Aug 2026 NCT06319820
active not recruiting Phase II / Phase III Dermatology
Long-Term Safety and Efficacy Evaluation of Amlitelimab in Participants of Previous Amlitelimab Moderate to Severe Atopic Dermatitis Clinical Trials
Long-term safety and efficacy study of amlitelimab for moderate-to-severe atopic dermatitis, including drug withdrawal to assess treatment durability.
27 Aug 2026 NCT05492578
active not recruiting Phase III
A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With Pyruvate Kinase Deficiency (PKD) Who Are Regularly Transfused, Followed by a 5-Year Extension Period
Mitapivat reduces transfusion need in children with pyruvate kinase deficiency compared to placebo.
27 Aug 2026 NCT05144256
active not recruiting Phase III Oncology
HERTHENA-Lung02: A Study of Patritumab Deruxtecan Versus Platinum-based Chemotherapy in Metastatic or Locally Advanced EGFRm NSCLC After Failure of EGFR TKI Therapy
HERTHENA-Lung02 Summary Patritumab deruxtecan compared to chemotherapy for advanced lung cancer with EGFR mutations that stopped responding to targeted drugs.
27 Aug 2026 NCT05338970
● Recruiting Phase III
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Palmoplantar Pustulosis
Bimekizumab was tested against placebo in patients with palmoplantar pustulosis to assess its effectiveness and safety.
27 Aug 2026 NCT07219420
● Recruiting Phase I Respiratory / COPD / Asthma
A Study to Evaluate Pharmacokinetics, Safety, and Tolerability of Two GSK3862995B Formulations in Healthy Participants
What is being tested: Two different formulations of GSK3862995B, an investigational medicine, are being compared to evaluate their pharmacokinetics (absorption, distribution, metabolism, and elimination),…
27 Aug 2026 NCT07789899
● Recruiting Phase III Oncology
Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
What is being tested: Daraxonrasib, a novel RAS(ON) inhibitor, evaluated both as monotherapy and in combination with gemcitabine/nab-paclitaxel (GnP) chemotherapy versus standard chemotherapy alone…
27 Aug 2026 NCT07491445
● Recruiting Oncology
A Multimodal Integrated Intervention for Kidney Cachexia
Combined exercise, dietary advice, and anti-inflammatory supplements may help prevent severe muscle wasting in haemodialysis patients.
26 Aug 2026 NCT07107087
active not recruiting Phase II Diabetes / Metabolic
HM15136 (Efpegerglucagon) Treatment for 8 Weeks in Subjects Aged ≥2 Years With Congenital Hyperinsulinism (CHI)
Eight-week study testing weekly injections of HM15136 as add-on treatment for children with congenital hyperinsulinism who remain hypoglycaemic.
26 Aug 2026 NCT04732416
● Recruiting
An Observational Study to Collect Data on How Aflibercept (Eylea) Given Using a Paediatric Dosing Device is Used in Preterm Babies With Retinopathy of Prematurity in the United Kingdom (UK)
UK study collecting data on how many premature babies receive eye injections of aflibercept for retinopathy using a special dosing device.
26 Aug 2026 NCT06315556
active not recruiting Phase III Neurology
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer’s Disease (TRAILBLAZER-ALZ 2)
Donanemab slows cognitive decline in early Alzheimer's disease; follow-up study monitors long-term safety and effectiveness.
26 Aug 2026 NCT04437511
● Recruiting
Satiety, Microbiome, Appetite Regulation, and Tracking Energy Across Targeted Snacks: Chronic Study
Seven-week remote study comparing two snack bars to assess effects on daily hunger, gut health, and digestive symptoms in healthy adults.
26 Aug 2026 NCT07782593
active not recruiting Phase I Gastroenterology
A First-time in Human (FTIH) Study to Evaluate Safety, Tolerability, Pharmacokinetics and Target Engagement of GSK4528287 in Healthy Participants
A new experimental drug (GSK4528287) for inflammatory bowel disease is being tested in healthy volunteers for the first time to check safety and how…
26 Aug 2026 NCT06681181
active not recruiting Phase II
A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Sclerosing Cholangitis (PSC)
Volixibat tested for reducing itching in patients with PSC and potentially slowing disease progression.
26 Aug 2026 NCT04663308
active not recruiting Phase I / Phase II Oncology
Study of AZD5305 When Given in Combination With New Hormonal Agents in Patients With Metastatic Prostate Cancer
Trial testing whether combining AZD5305 with hormone therapies is safe and effective for advanced prostate cancer.
26 Aug 2026 NCT05367440
● Recruiting Phase I Rheumatology
Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants
Early-stage trial testing a new injection drug's safety, tolerability, and how the body processes it in patients with rheumatoid arthritis or lupus.
26 Aug 2026 NCT07201558
● Recruiting Cardiology / Cardiovascular
Pragmatic Randomised Trial of High Or Standard PHosphAte Targets in End-stage Kidney Disease (PHOSPHATE)
What is being tested: A pragmatic randomised controlled trial comparing the effects of high versus standard blood phosphate targets in patients with end-stage kidney…
26 Aug 2026 NCT03573089
● Recruiting Oncology
Cardiomyopathies and Heart Muscle Diseases: Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition
What is being tested: Advanced cardiac imaging techniques to detect and evaluate myocardial fibrosis progression in patients with cardiomyopathies and heart muscle diseases, focusing…
26 Aug 2026 NCT06409585
● Recruiting Phase I Oncology
Safety and Efficacy of VB10.16 and Pembrolizumab in Patients With Head-Neck Squamous Cell Carcinoma
What is being tested: VB10.16 (therapeutic DNA vaccine) combined with pembrolizumab (PD-1 inhibitor) in patients with unresectable recurrent or metastatic HPV16-positive oropharyngeal head and…
26 Aug 2026 NCT06016920
● Recruiting Oncology
The PROSECCA Study, Answering New Questions in Prostate Cancer
What is being tested: The PROSECCA study evaluates radiotherapy techniques and strategies for prostate cancer treatment, specifically investigating methods to minimise damage to healthy…
26 Aug 2026 NCT06714630
active not recruiting Phase II Oncology
Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)
Entrectinib treats solid cancers with specific genetic fusions (NTRK, ROS1, ALK), grouped by cancer type and mutation.
25 Aug 2026 NCT02568267
active not recruiting Phase I Oncology
Study of TSR-042, an Anti-programmed Cell Death-1 Receptor (PD-1) Monoclonal Antibody, in Participants With Advanced Solid Tumors
Phase 1 trial testing dostarlimab, a new PD-1 immunotherapy antibody, for safety and effectiveness in advanced cancer patients.
25 Aug 2026 NCT02715284
active not recruiting Phase III
A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa
Long-term safety and effectiveness study of povorcitinib for moderate to severe hidradenitis suppurativa in patients completing earlier trials.
25 Aug 2026 NCT06212999
active not recruiting Rheumatology
Anatomical Shoulder Domelock System Study
This study confirms a new shoulder replacement system is safe and works well by checking patient scores, X-rays and complications.
25 Aug 2026 NCT03312465
active not recruiting Phase II
Study to Evaluate Tulisokibart for Hidradenitis Suppurativa (MK-7240-012)
Tulisokibart tested against placebo in moderate-to-severe skin infection; primary outcome was 50% symptom improvement at 16 weeks.
25 Aug 2026 NCT06956235
● Recruiting Respiratory / COPD / Asthma
The Role of METhanogens in the PROgression Of Parkinson’s Disease and Related Neurological Conditions
What is being tested: The study investigates whether methane-producing gut bacteria (methanogens) contribute to Parkinson's disease progression and related neurological conditions, examining the mechanistic…
25 Aug 2026 NCT07786116
● Recruiting Cardiology / Cardiovascular
Feasibility of a Physiotherapy Programme, With Integrated telerehabIlitation to Increase Rehabilitation Time and Improve Motor Function
What is being tested: A physiotherapy programme incorporating telerehabiliation technology designed to increase total rehabilitation time and improve motor function recovery in stroke patients.…
25 Aug 2026 NCT06871878
● Recruiting Phase III Oncology
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
What is being tested: Daraxonrasib (RMC-6236), a novel RAS(ON) inhibitor, is being evaluated for safety and efficacy as adjuvant therapy in resected pancreatic ductal…
25 Aug 2026 NCT07252232
● Recruiting Phase I Dermatology
A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK)
Study comparing how the body processes nusinersen delivered via an implantable device versus lumbar puncture in spinal muscular atrophy patients.
24 Aug 2026 NCT06555419
active not recruiting Oncology
PASS of Paediatric Patients Initiating Selumetinib
Study monitoring safety of selumetinib (a cancer drug) in children with neurofibromatosis type 1 nerve tumours in routine clinical practice.
24 Aug 2026 NCT05388370
active not recruiting Phase III
Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY)
Anifrolumab injection versus placebo tested in early systemic sclerosis patients to assess effectiveness and safety.
24 Aug 2026 NCT05925803
● Recruiting Phase II Rheumatology
A Study of Zasocitinib (TAK-279) in Adults With Active Crohn’s Disease
What is being tested: Zasocitinib (TAK-279), an investigational therapy targeting cellular and molecular mechanisms of inflammation, is being evaluated for its efficacy in treating…
24 Aug 2026 NCT07403968
● Recruiting Phase II Respiratory / COPD / Asthma
Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Idiopathic Pulmonary Fibrosis
What is being tested: ABBV-142, an investigational therapeutic agent, is being evaluated for its safety profile and effects on disease progression in adult patients…
24 Aug 2026 NCT07230288
● Recruiting Gastroenterology
Plant-Protein Dominant Tube Feed Study
Plant-based tube feeds tested against animal-based feeds for home patients over 12 months, measuring tolerance, compliance, and physical outcomes.
21 Aug 2026 NCT07422935
active not recruiting Phase III
A Study to Evaluate the Safety and Efficacy of Zilganersen (ION373) in Patients With Alexander Disease (AxD)
Zilganersen improves or stabilizes movement in patients with Alexander disease, a rare neurological disorder.
21 Aug 2026 NCT04849741
active not recruiting Phase III Cardiology / Cardiovascular
Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury
Botulinum toxin injections tested against placebo for treating leg stiffness after stroke or brain injury.
21 Aug 2026 NCT03992404
● Recruiting Cardiology / Cardiovascular
Comparing the Effects of Newer Pacemakers and Their Effects on the Heart and Valve Function in the Short-term.
What is being tested: This trial compares conventional pacemakers (with transvalvular leads through the heart valve) against newer pacemaker designs to evaluate their effects…
21 Aug 2026 NCT07534917
● Recruiting Phase III Oncology
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
What is being tested: Sofetabart Mipitecan (Sofe-M), a novel therapeutic agent being evaluated across three study parts in patients with ovarian, peritoneal, and fallopian…
21 Aug 2026 NCT07213804
active not recruiting Phase II Oncology
A Study to Learn About the Study Medicine Called PF-07220060 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment
Trial testing PF-07220060 with fulvestrant versus standard treatment in advanced hormone-receptor-positive breast cancer.
20 Aug 2026 NCT06105632
● Recruiting Phase II Gastroenterology
Efficacy and Safety of Vamifeport in Adult Participants With Homeostatic Iron Regulator Gene (HFE)-Related Hereditary Hemochromatosis
Vamifeport reduced liver iron levels in adults with hereditary hemochromatosis, a genetic iron overload disorder.
20 Aug 2026 NCT07332091
● Recruiting Gastroenterology
How the Brain and Body Recover After a Wrist Fracture
Study testing whether blood markers, brain scans, and body-map tests can predict who develops chronic pain after wrist fracture.
20 Aug 2026 NCT07777081
active not recruiting Phase III Oncology
A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants With Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-Mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC)
Adding niraparib to standard prostate cancer treatment improves progression-free survival in men with specific DNA repair gene mutations.
20 Aug 2026 NCT04497844
active not recruiting
Observational GORE® VIABAHN® Endoprosthesis With PROPATEN Bioactive Surface Global Registry
Registry tracking real-world outcomes in patients receiving Gore Viabahn stent grafts with bioactive surface coating.
20 Aug 2026 NCT04907240
● Recruiting Mental Health / Psychiatry
The Effect of 5-hydroxytryptophan on ADHD Traits and Eye Movements
Trial testing whether a natural supplement (5-HTP) can improve concentration and attention problems by increasing serotonin levels.
20 Aug 2026 NCT07777328
active not recruiting Oncology
Chemotherapy and Maximal Tumor Debulking of Multi-organ Colorectal Cancer Metastases
Chemotherapy plus surgery/ablation versus chemotherapy alone for colorectal cancer spread to multiple organs.
20 Aug 2026 NCT01792934