Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Rheumatology Women's Health Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Clinical Trial ● Currently Recruiting Non-phase study NCT07864051

Predicting Plaque Growth Using Blood Flow Stress Markers: A Proof-of-Concept Study

Predicting Plaque Growth Using Blood Flow Stress Markers: A Proof-of-Concept Study — Recruiting • Non-phase study • Cardiology / Cardiovascular • NCT07864051.

📅 07 Oct 2026 ⏱ 2 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Non-phase study
NCT ID
NCT07864051
Sponsor
Queen Mary University of London
Start
2026-09-17
ClinicaliQ Trial Snapshot
  • Predicting Plaque Growth Using Blood Flow Stress Markers: A Proof-of-Concept Study — Recruiting • Non-phase study • Cardiology / Cardiovascular • NCT07864051.
  • What is being tested: Blood flow stress markers (biomechanical indicators) are being evaluated as predictive tools to identify which coronary artery plaques will progress or rupture, rather than remain stable.
  • Patient eligibility overview: The study includes patients with established coronary artery disease who have identifiable plaques; specific inclusion/exclusion criteria would determine suitability based on disease severity, imaging findings, and cardiac stability.
Use This Page For
  • Quick orientation before opening the registry record.
  • Checking recruitment status, phase and sponsor at a glance.
  • Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying

Coronary artery disease occurs when fatty deposits (plaques) build up inside the arteries that supply blood to the heart. Some plaques remain stable, while others continue to grow or become more likely to rupture, which can lead to a heart attack. Identifying plaques that are at higher risk of progression could help doctors provide earlier and more personalized treatment. The purpose of this study is to determine whether combining information about blood flow within the coronary arteries with information about a person's biological response to blood flow can improve prediction…

Eligibility Snapshot
  • : 1. Age ≥40 2. Stable angina, defined as typical symptoms with evidence of reversible ischemia in non-invasive test and/or documented obstructive coronary artery disease on coronary angiography (>70% stenosis of at least one major epicardial coronary artery or positive fractional flow reserve study)
  • Patient that is willing and can provide written informed consent.

Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
View Trial ↗
Share: Twitter/X LinkedIn
Related

Related Clinical Intelligence

Guidelines, Drug Science, safety briefs and education connected to this trial area.

Clinical Brief
Weight-loss jabs will be offered on NHS for people at risk of further heart attacks
Cardiology / Cardiovascular · BBC Health · 31 Mar 2026
GLP-1 receptor agonists (weight-loss jabs) will now be offered on NHS to over 1 million people in England at high cardiovascular risk,…
View brief →
Guideline
Artificial intelligence (AI)-assisted echocardiography analysis and reporting to support the diagnosis and monitoring of heart failure: early-use assessment
Cardiology / Cardiovascular · 19 May 2026
AI-assisted echocardiography can support faster preliminary analysis and reporting of echo images in heart failure patients, potentially reducing reporting delays and improving…
View guideline →
Guideline
2023 ESC Guidelines for the Management of Acute Coronary Syndromes
Cardiology / Cardiovascular · 30 Mar 2026
Covers rapid diagnosis and risk stratification for acute coronary syndromes (ACS) including STEMI and NSTEMI • Provides evidence-based recommendations for reperfusion strategies…
View guideline →
Clinical Brief
Dad thankful charity scan revealed ‘silent’ heart attack
Cardiology / Cardiovascular · BBC Health · 10 Oct 2026
Asymptomatic coronary artery disease can be clinically significant—charity screening identified a blocked artery in a patient without symptoms, prompting necessary intervention Opportunistic…
View brief →
Guideline
Semaglutide for reducing the risk of major adverse cardiovascular events in people with cardiovascular disease and overweight or obesity
Cardiology / Cardiovascular · 07 May 2026
Semaglutide is recommended for adults with established cardiovascular disease and overweight/obesity to reduce major adverse cardiovascular events – consider prescribing as part…
View guideline →
Clinical Brief
The children dying in India’s remote tribal heartland
Cardiology / Cardiovascular · BBC Health · 30 Sep 2026
Measles and malaria resurgence in vulnerable populations: At least 32 child deaths in Balaghat district highlight ongoing risks in remote tribal areas…
View brief →