Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Rheumatology Women's Health Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

1963 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

1963 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting
Total Shoulder Arthroplasty Multi-Center Registry
A multi-centre study tracking clinical outcomes in patients having anatomic or reverse total shoulder replacement surgery.
20 Aug 2026 NCT03511586
● Recruiting Phase I Neurology
A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL921 in Healthy Participants and Participants With Alzheimer’s Disease
Drug being tested: DNL921 is a novel investigational agent undergoing Phase 1/1b evaluation for safety, tolerability, pharmacokinetics, and pharmacodynamics in both healthy volunteers and…
20 Aug 2026 NCT07758595
● Recruiting Respiratory / COPD / Asthma
UK SMA Patient Registry
What is being tested: The UK SMA Patient Registry is establishing a comprehensive database to collect clinical, genetic, and outcome data from patients with…
20 Aug 2026 NCT04292574
● Recruiting Cardiology / Cardiovascular
Severe Complications During Ventricular Tachycardia or Premature Ventricular Complex Ablation
What is being tested: This observational study characterizes severe complications occurring during ventricular tachycardia (VT) and premature ventricular complex (PVC) ablation procedures, collecting retrospective…
20 Aug 2026 NCT07777744
● Recruiting Phase I Cardiology / Cardiovascular
A Study Evaluating the Safety, Pharmacokinetics, and Activity of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma
Treatment being tested: Cevostamab (a novel therapeutic agent) administered as monotherapy or in combination with established multiple myeloma regimens (pomalidomide/dexamethasone or daratumumab/dexamethasone) to evaluate…
20 Aug 2026 NCT04910568
active not recruiting Phase II
Study of Efficacy and Safety of Tisagenlecleucel in HR B-ALL EOC MRD Positive Patients
Tisagenlecleucel CAR-T cell therapy for high-risk B-cell leukaemia patients with minimal residual disease after initial treatment.
19 Aug 2026 NCT03876769
● Recruiting Phase II Dermatology
Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis
Multi-drug trial testing new treatments for moderate to severe eczema in adults.
19 Aug 2026 NCT06947993
active not recruiting Phase III
Phase 3b Study to Assess the Efficacy, Safety, and Tolerability of Remibrutinib in Comparison to Placebo, With Omalizumab as Active Control, in Adult CSU Patients, Followed by an Open-label 52-week Optional Extension.
Remibrutinib versus placebo and omalizumab for chronic urticaria uncontrolled by antihistamines over 24-52 weeks.
19 Aug 2026 NCT06042478
● Recruiting
Impact of Footwear on Gait in Unilateral Transtibial Amputees
Study testing whether different shoe types affect walking ability, balance and comfort in amputees using prosthetic legs.
19 Aug 2026 NCT07685496
● Recruiting Oncology
A Study to Identify Breast Cancer (IDBC)
What is being tested: A novel blood-based diagnostic test (Syantra DX Breast Cancer) designed to identify breast cancer through biomarker detection in blood samples,…
19 Aug 2026 NCT04495244
● Recruiting Diabetes / Metabolic
Development of a Non-invasive Screening Tool to Predict Metabolic Dysfunction-associated Steatotic Liver Disease
What is being tested: Development and validation of a non-invasive screening tool to predict metabolic dysfunction-associated steatotic liver disease (MASLD), potentially replacing the need…
19 Aug 2026 NCT04873258
● Recruiting Phase III Cardiology / Cardiovascular
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
What is being tested: Oral levosimendan efficacy and safety in patients with pulmonary hypertension combined with heart failure with preserved ejection fraction (PH-HFpEF), with…
19 Aug 2026 NCT07288398
● Recruiting Phase III Cardiology / Cardiovascular
Roll-over Study for Participants Who Have Completed a Previous Clinical Study With Benralizumab (Fasenra) and Benefit From Continued Treatment
Treatment Being Tested: Continued access to benralizumab (Fasenra), a monoclonal antibody targeting IL-5 receptor alpha, for patients with eosinophilic airway diseases who have demonstrated…
19 Aug 2026 NCT07444567
● Recruiting Cardiology / Cardiovascular
Multimodal Biomarkers in Coronary Artery Disease Pathogenesis: The Oxford Acute Myocardial Infarction Study (OXAMI Study)
What is being tested: The study investigates multiple biomarkers (biological markers) to understand how coronary artery disease develops and progresses, particularly in patients experiencing…
19 Aug 2026 NCT07772570
active not recruiting Phase III Oncology
Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer
Adding olaparib to abiraterone improves outcomes versus abiraterone alone in men with newly-diagnosed advanced prostate cancer.
18 Aug 2026 NCT03732820
● Recruiting Diabetes / Metabolic
GLycaemic Outcomes With Whey Protein in ageING
What is being tested: A placebo-controlled trial investigating whether consuming whey protein before meals improves glucose control in older adults with type 2 diabetes,…
18 Aug 2026 NCT07285811
● Recruiting Phase I Cardiology / Cardiovascular
A Research Study on the Effects of NNC0537-1482 in Participants With Heart Failure
Investigational Agent: NNC0537-1482 is a novel drug being evaluated for safety, tolerability, and pharmacological efficacy in heart failure patients—addressing an unmet therapeutic need in…
18 Aug 2026 NCT07218627
● Recruiting Oncology
Long-term Safety of Nipple Sparing Mastectomy in Women With High Penetrance Breast Cancer Susceptibility Genes in Breast Cancer
What is being tested: Long-term safety outcomes of nipple-sparing mastectomy (NSM) as a risk-reducing procedure in women carrying high-penetrance breast cancer susceptibility gene mutations…
18 Aug 2026 NCT06888388
● Recruiting Phase III Diabetes / Metabolic
A Phase 3 Study of Ersodetug in Patients With Tumor Hyperinsulinism
Study testing whether ersodetug added to standard treatment reduces low blood sugar episodes in patients with insulin-producing tumours.
17 Aug 2026 NCT06881992
active not recruiting Phase I
A Study Evaluating the Safety, Pharmacokinetics, and Activity of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma
Early-stage trial testing a new antibody drug (cevostamab) alone or combined with existing treatments for hard-to-treat multiple myeloma.
17 Aug 2026 NCT04910568
active not recruiting Phase II Rheumatology
A Study Evaluating the Efficacy and Safety of Afimetoran Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)
Trial testing whether a new drug called Afimetoran works better than placebo for treating active lupus.
17 Aug 2026 NCT04895696
● Recruiting Gastroenterology
A Prospective Study of Pediatric Participants up to 16 Years of Age With Methylmalonic Acidemia (MMA) Due to Mutations in the MMUT Gene
Study Summary for UK Clinicians This observational study tracks children with methylmalonic acidemia to identify reliable blood markers and clinical signs indicating disease activity…
17 Aug 2026 NCT07432880
● Recruiting Phase II Oncology
A PoC Study to Evaluate Treatments’ Efficacy by Monitoring MRD Using ctDNA in HR-positive/HER2-negative EBC Population
What is being tested: A phase II study evaluating adjuvant treatment efficacy in HR-positive/HER2-negative early breast cancer by using circulating tumour DNA (ctDNA) as…
17 Aug 2026 NCT05708235
● Recruiting Phase III Respiratory / COPD / Asthma
A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma
What is being tested: Depemokimab, a novel biologic therapy, is being evaluated as an add-on treatment to standard care in Type 2 asthma patients…
17 Aug 2026 NCT07456033
● Recruiting Phase II Oncology
DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.
Treatment Being Tested: The combination of dabrafenib (a BRAF inhibitor) and trametinib (a MEK inhibitor) in patients with BRAF V600 mutation-positive cancers across multiple…
17 Aug 2026 NCT07440290
● Recruiting Cardiology / Cardiovascular
Arterial Stiffness in Children and Young People With Hypertension and Chronic Kidney Disease
What is being tested: The study investigates arterial stiffness (hardening of arteries) in children and young people with hypertension and/or chronic kidney disease, examining…
17 Aug 2026 NCT07768865
● Recruiting Cardiology / Cardiovascular
Nailfold Capillaroscopy in PH
What is being tested: Nailfold capillaroscopy (microscopic examination of blood vessels in the nail fold) as a non-invasive diagnostic tool to identify pulmonary hypertension…
17 Aug 2026 NCT07768644
● Recruiting Phase II Oncology
A Study to Find Out if Enfortumab Vedotin Given With Pembrolizumab Helps People With Muscle-invasive Bladder Cancer Keep Their Bladder
What is being tested: The combination of enfortumab vedotin (an antibody-drug conjugate targeting Nectin-4) with pembrolizumab (a PD-1 checkpoint inhibitor) as a bladder-preserving alternative…
17 Aug 2026 NCT07475806
● Recruiting Phase III Respiratory / COPD / Asthma
Study of Oral Upadacitinib and Subcutaneous/Intravenous Tocilizumab to Evaluate Change in Disease Activity, Adverse Events and How Drug Moves Through the Body of Pediatric and Adolescent Participants With Active Systemic Juvenile Idiopathic Arthritis.
Trial testing upadacitinib tablet/liquid versus tocilizumab injection/infusion for systemic juvenile arthritis in children aged 1-18 over 52 weeks.
14 Aug 2026 NCT05609630
● Recruiting Phase II / Phase III Oncology
A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma
Trial testing new drug telisotuzumab adizutecan combined with chemotherapy versus standard treatment for advanced pancreatic cancer.
14 Aug 2026 NCT07490301
active not recruiting Phase III Oncology
A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)
Testing two new drug combinations against standard treatment for advanced kidney cancer, measuring survival and disease progression.
14 Aug 2026 NCT04736706
active not recruiting Phase I / Phase II Oncology
Safety and Pharmacokinetics of ODM-208 in Patients With Metastatic Castration-resistant Prostate Cancer
ODM-208 showed acceptable safety in advanced prostate cancer patients, supporting further development of this new treatment.
14 Aug 2026 NCT03436485
● Recruiting Rheumatology
Perform Humeral System Study
Study tracking safety and outcomes of a shoulder implant system over 10 years following surgery.
14 Aug 2026 NCT05067543
active not recruiting Phase II / Phase III
A Study to Assess the Efficacy and Safety of Weekly Doses of GLM101 in Participants With PMM2-CDG
Weekly GLM101 treatment tested against placebo for a rare genetic disorder affecting protein processing in children and adults.
14 Aug 2026 NCT06892288
● Recruiting Phase III Infectious Disease
A Study to Investigate Cabotegravir Ultra Long-Acting (CAB ULA) Plus Rilpivirine Ultra Long-Acting (RPV ULA) in Adults and Adolescents With HIV Who Are Virologically Suppressed
What is being tested: Cabotegravir ultra long-acting (CAB ULA) plus rilpivirine ultra-acting (RPV ULA) injections are being compared against standard long-acting formulations (CAB LA…
14 Aug 2026 NCT07650916
● Recruiting Phase II Respiratory / COPD / Asthma
Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis
What is being tested: CSL889 (human hemopexin) administered intravenously in a phase 2 randomized controlled trial to evaluate safety, efficacy, and pharmacokinetics in managing…
14 Aug 2026 NCT06699849
● Recruiting Phase III Diabetes / Metabolic
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
What is being tested: ASC30, an oral once-daily medication, is being evaluated for efficacy and safety in reducing weight and improving glycaemic control in…
14 Aug 2026 NCT07743450
● Recruiting Cardiology / Cardiovascular
Coroflex® ISAR NEO PMCF Study
Device being tested: The Coroflex® ISAR NEO coronary stent system is undergoing post-market clinical follow-up to verify its safety and performance profile in real-world…
14 Aug 2026 NCT05698732
● Recruiting Phase III Cardiology / Cardiovascular
Study of AZD0120 in Newly Diagnosed Multiple Myeloma Ineligible for ASCT
What is being tested: AZD0120 (a novel therapeutic agent) as consolidation/maintenance therapy following standard induction regimens (IsaVRd or DRd) compared to continuous standard therapy…
14 Aug 2026 NCT07764978
● Recruiting Phase II Cardiology / Cardiovascular
A Study of TAK-755 in Adults With Acute Ischemic Stroke
What is being tested: TAK-755, an investigational therapeutic agent, is being evaluated for safety and efficacy in treating acute ischemic stroke caused by blood…
14 Aug 2026 NCT07392450
● Recruiting Cardiology / Cardiovascular
Microvascular Coronary Rehabilitation For Improving Treatment – Feasibility Study
What is being tested: A personalised cardiac rehabilitation programme called MICROFIT combining high-intensity interval exercise (HIIT) and dietary advice, designed to improve outcomes in…
14 Aug 2026 NCT06681896
● Recruiting Oncology
Exploring Resistance Exercise Training Plus High-Intensity Interval Training (ReHIIT) as Cancer Prehabilitation
What is being tested: A combined prehabilitation programme (ReHIIT) integrating resistance exercise training with high-intensity interval training in healthy adults to establish baseline physiological…
14 Aug 2026 NCT07313332
● Recruiting Phase III Oncology
A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031)
What is being tested: Sacituzumab tirumotecan (sac-TMT), an antibody-drug conjugate targeting Trop-2, is being evaluated as a potential new treatment for locally advanced or…
14 Aug 2026 NCT07419295
active not recruiting Rheumatology
H1 Hip Resurfacing Arthroplasty
Study tracking safety and effectiveness of ceramic hip resurfacing implant over ten years, comparing it to metal versions.
13 Aug 2026 NCT03326804
active not recruiting Phase III Oncology
OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer
Palazestrant versus standard hormone therapy in advanced breast cancer that's progressed on previous endocrine treatment plus CDK4/6 inhibitor.
13 Aug 2026 NCT06016738
● Recruiting Phase I / Phase II Neurology
A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)
Gene therapy AVB-101 delivered to the brain as one-time treatment for early-onset dementia caused by progranulin protein deficiency.
13 Aug 2026 NCT06064890
active not recruiting Phase III Dermatology
A Research Study on How Well Concizumab Works for You if You Have Haemophilia A or B With or Without Inhibitors
Concizumab daily injections tested in haemophilia A/B patients to prevent bleeds over 2-4 years.
13 Aug 2026 NCT05135559
active not recruiting Phase I Oncology
Tuvusertib (M1774) in Participants With Metastatic or Locally Advanced Unresectable Solid Tumors (DDRiver Solid Tumors 301)
Early-stage study testing a new cancer drug (tuvusertib) alone and combined with niraparib in advanced solid tumors to assess safety and effectiveness.
13 Aug 2026 NCT04170153
active not recruiting Phase III
A Study of Bomedemstat (IMG-7289/MK-3543) Compared to Best Available Therapy (BAT) in Participants With Essential Thrombocythemia and an Inadequate Response or Intolerance of Hydroxyurea (MK-3543-006)
New drug bomedemstat compared to standard treatment for essential thrombocythemia patients who don't respond to or tolerate hydroxyurea.
13 Aug 2026 NCT06079879
active not recruiting Mental Health / Psychiatry
Feasibility of a Compassionate Mindful Resilience Programme for Thai Secondary School Students
A feasibility study testing whether a culturally adapted mindfulness and compassion programme is acceptable and deliverable in Thai secondary schools.
13 Aug 2026 NCT07482839