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Trial Radar

1003 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

1003 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Mental Health / Psychiatry
Post Intensive Care Accelerometery to Study and Support Recovery Outcomes
Wrist activity monitors track ICU patients' recovery at home to identify problems early and guide support.
04 May 2026 NCT07466446
active not recruiting Phase III
Oral N-acetylcysteine for Retinitis Pigmentosa
NAC supplement may slow vision loss in retinitis pigmentosa by reducing oxidative stress; ongoing trials testing long-term effectiveness.
04 May 2026 NCT05537220
active not recruiting Oncology
Measuring and Mapping Cognitive Decline After Brain Radiosurgery
Study tests whether brain radiosurgery for tumours damages thinking ability and identifies brain areas at risk to spare during future treatment.
04 May 2026 NCT06466720
● Recruiting Phase III
A 52-week Study of Rilzabrutinib Efficacy and Safety Compared to Placebo in Adults Diagnosed With IgG4-related Disease
Rilzabrutinib reduces disease flares and controls IgG4-related disease activity better than placebo over 52 weeks in adults.
04 May 2026 NCT07190196
● Recruiting Cardiology / Cardiovascular
Cryoballoon/Radiofrequency/Pulsed Field Ablation of Atrial Fibrillation Versus Medical Treatment for Heart
What is being tested: This trial compares three catheter ablation techniques (cryoballoon, radiofrequency, and pulsed field ablation) against standard medical management (rate control and…
04 May 2026 NCT06505798
● Recruiting Infectious Disease
CERAMENT G as Part of the Surgical Treatment of Osteomyelitis in a Single-Stage Procedure
What is being tested: CERAMENT G (an antibiotic-loaded bone void filler) is being evaluated as part of single-stage surgical treatment for osteomyelitis, combining debridement…
04 May 2026 NCT06555848
● Recruiting Phase II Respiratory / COPD / Asthma
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma
Treatment being tested: PF-07275315, an investigational medicine for moderate-to-severe asthma, with assessment of its safety profile and clinical efficacy in reducing breathing difficulties. Patient…
04 May 2026 NCT06977581
● Recruiting Phase III Respiratory / COPD / Asthma
A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease
What is being tested: The efficacy and safety of axatilimab (a CD40 ligand antagonist) combined with corticosteroids versus placebo plus corticosteroids as first-line treatment…
04 May 2026 NCT06585774
● Recruiting Cardiology / Cardiovascular
Acute Impact of Whey Protein-enriched Milk Fat Globule Membrane Supplementation on Postprandial Markers of Heart and Brain Health
What is being tested: The acute effects of whey protein-enriched milk fat globule membrane (MFGM) supplementation added to a high-fat meal on postprandial cardiovascular…
04 May 2026 NCT06953232
● Recruiting Phase II Cardiology / Cardiovascular
A Gene Therapy Study of RP-A501 in Male Patients With Danon Disease
RP-A501 is a gene therapy using AAV9 vector to deliver the LAMP2B gene – designed to address the underlying genetic defect in Danon disease…
04 May 2026 NCT06092034
● Recruiting Phase III Oncology
Study of Revumenib in Combination With Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia (AML) With a NPM1 Mutation
What is being tested: Revumenib, a menin inhibitor, combined with intensive chemotherapy versus chemotherapy alone in newly diagnosed AML patients with NPM1 mutations, evaluating…
04 May 2026 NCT07211958
● Recruiting Phase I Oncology
A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors
What is being tested: GDC-7035, a novel investigational agent, is undergoing first-in-human evaluation for safety, pharmacokinetics, and anti-cancer activity both as monotherapy and in…
04 May 2026 NCT06619587
● Recruiting Phase I Oncology
First-in-human Study of IDRX-42 in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumors
This is the first clinical trial of IDRX-42. The study is designed to evaluate the safety, tolerability, PK, and preliminary antitumor activity of IDRX-42…
04 May 2026 NCT05489237
● Recruiting Phase I Oncology
Study of an AAV Mediated Dual-Payload Gene Therapy in Patients With High Grade Glioma
The goal of this clinical trial is to first define the Safety and Optimal Biological Dose (OBD) of study drug TGX-007 and to then…
04 May 2026 NCT07346144
● Recruiting Diabetes / Metabolic
Assessing the Dose-response of Muscle Protein Synthesis to “Super-whey” in Older Adults
One-sentence summary: This study tests three doses of leucine-enriched whey protein to find which best stimulates muscle building in older people.
01 May 2026 NCT05700058
● Recruiting Phase III Rheumatology
A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus
Dapirolizumab pegol added to standard treatment improves moderate to severe lupus disease activity.
01 May 2026 NCT06617325
● Recruiting Gastroenterology
Drivers and Barriers for Adopting Healthy and Sustainable Food Swaps in Young
Study tests whether personalised approaches help young adults swap red meat for fish or plants, improving health markers.
01 May 2026 NCT06714656
● Recruiting Gastroenterology
Fast Food Online Delivery Purchase Behaviour in the Presence and Absence of Price-based Incentives
Removing price discounts from fast food delivery apps slightly reduced calorie selections, but effects were unclear and based on hypothetical choices only.
01 May 2026 NCT07368881
active not recruiting Phase III Oncology
Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) Versus CRT Alone in Muscle-invasive Bladder Cancer (MIBC) (MK-3475-992/KEYNOTE-992)
Adding pembrolizumab immunotherapy to chemoradiotherapy improves survival and delays cancer progression in muscle-invasive bladder cancer patients avoiding surgery.
01 May 2026 NCT04241185
active not recruiting Phase III Gastroenterology
Study of Elafibranor in Patients With Primary Biliary Cholangitis (PBC)
Elafibranor tested against placebo in PBC patients inadequately responding to ursodeoxycholic acid, assessing alkaline phosphatase reduction and safety.
01 May 2026 NCT04526665
active not recruiting Phase III Oncology
Study of Durvalumab With Tremelimumab Versus SoC as 1st Line Therapy in Metastatic Non Small-Cell Lung Cancer (NSCLC) (NEPTUNE)
Two immunotherapy drugs versus standard chemotherapy for advanced lung cancer without specific genetic mutations.
01 May 2026 NCT02542293
active not recruiting Phase III Neurology
A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients With Multiple Sclerosis
Long-term safety and efficacy study of ocrelizumab, a B-cell depleting antibody, in multiple sclerosis patients continuing from previous trials.
01 May 2026 NCT05269004
● Recruiting
Prospective Follow-up of the Prevision Hip Stem With Comparison of Different Implant Variants
Long-term safety and performance study of different Prevision hip stem variants in routine clinical practice.
01 May 2026 NCT06626490
active not recruiting Phase III Mental Health / Psychiatry
A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama)
MM120 was tested against placebo for anxiety disorder in a large, rigorous trial with long-term follow-up.
01 May 2026 NCT06809595
● Recruiting Phase I Oncology
A Trial to Learn How Safe AZD9750 is and How Well it Works in People With Metastatic Prostate Cancer When Given With or Without Other Anticancer Drugs
What is being tested: AZD9750, a novel investigational agent, is being evaluated as monotherapy and in combination with saruparib (a PARP inhibitor) in metastatic…
01 May 2026 NCT07336446
● Recruiting Phase I Neurology
A Study of AZD0120 in Autoimmune Diseases
What is being tested: AZD0120, a dual-targeting CAR+ T-cell therapy that simultaneously targets BCMA and CD19, is being evaluated for safety and tolerability in…
01 May 2026 NCT07295847
● Recruiting Phase II
Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe Pruritus
What is being tested: Safety and tolerability of difelikefalin, a novel therapeutic agent, in adolescent patients undergoing haemodialysis who experience moderate-to-severe pruritus (a significant…
01 May 2026 NCT06593392
● Recruiting Phase II Gastroenterology
A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME)
Treatment being tested: ALG-000184, a novel oral antiviral agent administered once daily as monotherapy, compared against the established standard tenofovir disoproxil fumarate (TDF) in…
01 May 2026 NCT06963710
● Recruiting Cardiology / Cardiovascular
The Next Leap in Cardiac Magnetic Resonance Imaging:Cycling the Field
What is being tested: Development and clinical validation of a custom-built cardiac coil designed specifically for a whole-body Field-Cycling MRI (FFC-MRI) prototype to enable…
01 May 2026 NCT04458883
● Recruiting Phase I Cardiology / Cardiovascular
A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease
What is being tested: FT819, a novel therapeutic agent targeting B-cell activity, is being evaluated for safety, pharmacokinetics, and anti-B-cell efficacy in patients with…
01 May 2026 NCT06308978
● Recruiting Phase II Cardiology / Cardiovascular
Coronary Artery Stents in Heart Failure With Preserved Ejection Fraction
What is being tested: This trial evaluates whether coronary artery stent placement improves outcomes in patients with HFpEF who have concurrent coronary artery disease,…
01 May 2026 NCT07560436
● Recruiting Cardiology / Cardiovascular
Multicentre Hypertrophic Cardiomyopathy Registry
What is being tested: A multicentre registry collecting comprehensive clinical data on hypertrophic cardiomyopathy patients to understand disease progression, phenotypes, and outcomes across diverse…
01 May 2026 NCT07381894
● Recruiting Phase I Oncology
Clinical Study to Assess the Safety and Efficacy of the SpectraCure P18 System
What is being tested: The SpectraCure P18 System combined with verteporfin (a photosensitizer) is being evaluated for safety, efficacy, and optimal dosing parameters in…
01 May 2026 NCT03067051
● Recruiting Phase II Oncology
A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer
What is being tested: ASP5541, a novel androgen receptor pathway inhibitor (ARPI), is being evaluated in a Phase 2 study as a potential treatment…
01 May 2026 NCT07005154
● Recruiting Phase II Oncology
A Study of Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement
Drug and target: Lirafugratinib, a selective FGFR2 inhibitor, is being tested in previously treated patients with advanced/metastatic solid tumours (excluding cholangiocarcinoma) that harbour FGFR2…
01 May 2026 NCT07359820
active not recruiting Phase III Gastroenterology
A Study of Elafibranor in Adults With Primary Biliary Cholangitis and Inadequate Response or Intolerance to Ursodeoxycholic Acid.
Trial testing elafibranor versus placebo in primary biliary cholangitis patients who cannot tolerate or inadequately respond to ursodeoxycholic acid, measuring effects on alkaline phosphatase…
30 Apr 2026 NCT06383403
active not recruiting Phase III
A Study to Evaluate How Safe Pozelimab + Cemdisiran Combination Therapy is and How Well it Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have Not Recently Received or Have Not Received Complement Inhibitor Treatment
Two new PNH drugs (pozelimab + cemdisiran) tested for safety and effectiveness against existing complement inhibitor treatments.
30 Apr 2026 NCT05133531
active not recruiting
ADH1 and ADH2 Disease Monitoring Study (DMS)
Study tracking how autosomal dominant hypocalcaemia types 1 and 2 develop and progress over time using patient medical records.
30 Apr 2026 NCT05227287
● Recruiting Phase I Dermatology
A 3-part Study of SYX-5219 in Healthy Volunteers and Participants With Atopic Dermatitis
Early-stage trial testing new drug SYX-5219 for safety and effectiveness in healthy people and atopic dermatitis patients.
30 Apr 2026 NCT07558668
● Recruiting
Diagnostic Accuracy of Oral Images, OPGs, Biomarkers and Questionnaires vs. Clinical Assessment for Periodontal Disease (PostNCT07164573)
Study tests whether photos, scans, saliva tests and questionnaires can accurately detect gum disease compared to clinical examination.
30 Apr 2026 NCT07406867
● Recruiting Gastroenterology
VertiGreens Investigating the Effects of Iron Biofortification of Microgreens on Iron Status in Women
Iron-enriched microgreens in smoothies for 28 days improve iron levels in women, assessed via blood tests and dietary tracking.
30 Apr 2026 NCT06972927
active not recruiting Phase II
A Study to Evaluate RO7204239 in Participants With Facioscapulohumeral Muscular Dystrophy
A study testing a new antibody drug to block myostatin in adults with facioscapulohumeral muscular dystrophy.
30 Apr 2026 NCT05548556
active not recruiting Diabetes / Metabolic
The SPECTRUM Study: An Observational Study to Learn More About How Well Aflibercept 8 mg Works in Treating Visual Impairment Due to Neovascular Age-related Macular Degeneration or Diabetic Macula Edema
Real-world study collecting data on vision outcomes in patients with wet macular degeneration or diabetic eye swelling treated with aflibercept 8mg injections.
30 Apr 2026 NCT06075147
active not recruiting Phase IV
A Study to Determine the Efficacy, Safety, and Durability of Faricimab in Participants With Neovascular Age-Related Macular Degeneration
Faricimab injections given every 24 weeks or less maintain vision in treatment-naive wet age-related macular degeneration over 100 weeks.
30 Apr 2026 NCT06795048
active not recruiting Oncology
A Study of the Effectiveness of Cabozantinib in Combination With Nivolumab as First-line Treatment of Advanced Renal Cell Carcinoma (aRCC) in Adults
Cabozantinib plus nivolumab as first-line treatment for advanced kidney cancer: real-world safety and effectiveness study.
30 Apr 2026 NCT05361434
● Recruiting Phase III Oncology
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician’s Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
Treatment being tested: Sacituzumab govitecan-hziy (an antibody-drug conjugate targeting Trop-2) combined with pembrolizumab (PD-L1 inhibitor) versus physician's choice treatment in the adjuvant setting following…
30 Apr 2026 NCT05633654
● Recruiting Oncology
Sodium-glucose Transporter Type 2 Inhibition in Anthracycline-related Cardiotoxicity
What is being tested: SGLT2 inhibitors are being investigated as a potential preventive or therapeutic intervention for anthracycline-induced cardiotoxicity, a serious heart damage complication…
30 Apr 2026 NCT07070765
● Recruiting Phase III Oncology
Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen
What is being tested: Paltusotine, an oral daily medication, is being evaluated against placebo in a Phase 3 randomized controlled trial to assess its…
30 Apr 2026 NCT07087054
● Recruiting Gastroenterology
Drug-induced Liver Injury: Itching Study
What is being tested: The study investigates itching (pruritus) associated with drug-induced liver injury (DILI), specifically focusing on cholestatic or mixed-pattern hepatic reactions—an unpredictable…
30 Apr 2026 NCT06446609
● Recruiting Phase III Oncology
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients
Treatment Being Tested: Ivonescimab (a dual TIGIT/PD-L1 pathway inhibitor) combined with chemotherapy compared to pembrolizumab (PD-L1 inhibitor) combined with chemotherapy as first-line therapy for…
30 Apr 2026 NCT05899608