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Clinical Trial Active — Not Recruiting Non-phase study NCT04913987

Unicompartmental Versus Total Knee Replacement for Medial Compartment Knee Osteoarthritis

Unicompartmental Versus Total Knee Replacement for Medial Compartment Knee Osteoarthritis — Active Not Recruiting • Non-phase study • Rheumatology • NCT04913987.

📅 24 Sep 2026 ⏱ 2 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Non-phase study
NCT ID
NCT04913987
Start
2021-04-26
Completion
2027-10-15
ClinicaliQ Trial Snapshot
  • Unicompartmental Versus Total Knee Replacement for Medial Compartment Knee Osteoarthritis — Active Not Recruiting • Non-phase study • Rheumatology • NCT04913987.
  • FLEX-UNI trial compares partial versus total knee replacement for inner knee osteoarthritis using motion analysis during demanding activities like stair descent.

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What This Trial Is Studying

For patients with osteoarthritis affecting only the inner part of the knee, surgeons can offer either a partial knee replacement, which resurfaces the worn compartment alone, or a total knee replacement. Both are recommended treatments, but there is no agreement on when to choose one over the other. Partial knee replacement preserves the anterior cruciate ligament and more of the natural knee, and recovery is usually quicker, but it is used in only about one in ten knee replacements in the United Kingdom. Studies comparing the two have mostly relied…

Full Trial Details
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Eligibility criteria, protocol, and results when available
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