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Clinical Trial Active — Not Recruiting Phase I NCT04973163

A Study to Test Different Doses of BI 1823911 Alone and Combined With Other Medicines in People With Different Types of Advanced Cancer With KRAS Mutation

A Study to Test Different Doses of BI 1823911 Alone and Combined With Other Medicines in People With Different Types of Advanced Cancer With KRAS Mutation — Active…

📅 30 Sep 2026 ⏱ 2 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Phase I
NCT ID
NCT04973163
Start
2021-09-09
Completion
2026-11-29
ClinicaliQ Trial Snapshot
  • A Study to Test Different Doses of BI 1823911 Alone and Combined With Other Medicines in People With Different Types of Advanced Cancer With KRAS Mutation — Active Not Recruiting • Phase I • Oncology • NCT04973163.
  • Trial of BI 1823911 alone and combined with BI 1701963 in advanced KRAS-mutated cancers to find tolerable doses and tumour response.

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What This Trial Is Studying

This study is open to adults with different types of advanced or metastatic cancer (including lung cancer, colorectal cancer, pancreatic cancer, and bile duct cancer). This study is for people for whom previous treatment was not successful or no treatment exists. People who have a tumour with a KRAS mutation can participate in the study. A KRAS mutation makes tumours grow faster. BI 1823911 and BI 1701963 are medicines that may turn off KRAS, each in a different way. In this study, BI 1823911 is given to people for the…

Full Trial Details
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Eligibility criteria, protocol, and results when available
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