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Clinical Trial ● Currently Recruiting Phase II NCT07759245

A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)

A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD) — Recruiting • Phase II • Respiratory / COPD / Asthma • NCT07759245.

📅 25 Sep 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Phase II
NCT ID
NCT07759245
Sponsor
Eli Lilly and Company
Start
2026-08-07
ClinicaliQ Trial Snapshot
  • A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD) — Recruiting • Phase II • Respiratory / COPD / Asthma • NCT07759245.
  • Treatment being tested: Brenipatide (LY3537031), a novel therapeutic agent, is being evaluated at multiple dose levels versus placebo to assess safety and efficacy in adults with moderate-to-severe COPD.
  • Patient eligibility overview: The trial enrolls adult participants with confirmed moderate-to-severe COPD, representing a significant proportion of the COPD population who currently have limited therapeutic options beyond standard care.
Use This Page For
  • Quick orientation before opening the registry record.
  • Checking recruitment status, phase and sponsor at a glance.
  • Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying

The main purpose of this study is to assess if different dose levels of Brenipatide are safe and work the way they are intended to work in participants with moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD), when compared with placebo. The study will last approximately one year.

Eligibility Snapshot
  • : * Have a physician diagnosis of Chronic Obstructive Pulmonary Disease (COPD), at least 12 months prior to screening who meet the following criteria: * Current or former smokers with a smoking history of greater than or equal to (≥) 10 pack-years * Moderate-to-severe COPD (post-Bronchodilator (BD) Forced Expiratory Volume in 1 Second (FEV₁)/forced vital capacity (FVC) less than (

Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
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