Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Rheumatology Women's Health Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Clinical Trial ● Currently Recruiting Phase II / Phase III NCT07549321

A Safety and Efficacy Study of hu14 in High-Risk Neuroblastoma Patients

A Safety and Efficacy Study of hu14 in High-Risk Neuroblastoma Patients — Recruiting • Phase II / Phase III • Oncology • NCT07549321.

📅 23 Sep 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Phase II / Phase III
NCT ID
NCT07549321
Start
2026-03-30
Completion
2031-03
ClinicaliQ Trial Snapshot
  • A Safety and Efficacy Study of hu14 in High-Risk Neuroblastoma Patients — Recruiting • Phase II / Phase III • Oncology • NCT07549321.
  • Trial testing a new antibody drug combined with chemotherapy to treat high-risk neuroblastoma in young children.

Verify eligibility, endpoints and current status on the original ClinicalTrials.gov registry before acting on this summary.

Use This Page For
  • Quick orientation before opening the registry record.
  • Checking recruitment status, phase and sponsor at a glance.
  • Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying

Neuroblastoma is the most common type of solid cancer found outside the brain in young children. Generally, it affects children younger than 5 years old, with the average age when it is found being just 2 years. Most patients have 'high-risk' disease, with spread of the disease to different sites (metastases). This multinational study aims to find out how effective and safe the treatment of a monoclonal anti-GD2 antibody hu14.18K322A (daretabart) is when used together with chemotherapy to treat children and young people who have high-risk neuroblastoma. Conditions: High-Risk Neuroblastoma…

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
View Trial ↗
Share: Twitter/X LinkedIn
Related

Related Clinical Intelligence

Guidelines, Drug Science, safety briefs and education connected to this trial area.

Clinical Brief
New hope for breast cancer patients as life-extending drug now on NHS in England
Oncology · BBC Health · 16 Sep 2026
Enhertu is now available on the NHS in England, extending median overall survival by approximately seven months in eligible breast cancer patients…
View brief →
Clinical Brief
Targeted prostate cancer treatment cuts risk of side effects, study suggests
Oncology · BBC Health · 16 Jul 2026
Focal therapy for prostate cancer demonstrates reduced side effects compared to whole-gland treatments, based on a decade-long NHS trial of 3,500 men,…
View brief →
Guideline
Cemiplimab for treating recurrent or metastatic cervical cancer that has progressed on or after platinum-based chemotherapy
Oncology · 09 Jul 2026
Cemiplimab is recommended as a treatment option for patients with recurrent or metastatic cervical cancer only after progression on or following platinum-based…
View guideline →
Guideline
Serplulimab with carboplatin and etoposide for untreated extensive-stage small-cell lung cancer
Oncology · 18 Jun 2026
Serplulimab combined with carboplatin and etoposide is recommended as first-line treatment for untreated extensive-stage small-cell lung cancer (ES-SCLC) and should be considered…
View guideline →
Clinical Brief
Young women now have ‘close to zero’ risk of cervical cancer death after HPV jab
Oncology · BBC Health · 18 Jun 2026
The HPV vaccination programme introduced in 2008 has dramatically reduced cervical cancer mortality in vaccinated cohorts, with young women now facing near-zero…
View brief →
Guideline
Durvalumab with platinum-based chemotherapy, then with or without olaparib, for untreated advanced or recurrent endometrial cancer
Oncology · 09 Sep 2026
Durvalumab combined with platinum-based chemotherapy is the recommended first-line treatment for untreated advanced or recurrent endometrial cancer, with olaparib addition considered based…
View guideline →