- A Safety and Efficacy Study of hu14 in High-Risk Neuroblastoma Patients — Recruiting • Phase II / Phase III • Oncology • NCT07549321.
- Trial testing a new antibody drug combined with chemotherapy to treat high-risk neuroblastoma in young children.
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Neuroblastoma is the most common type of solid cancer found outside the brain in young children. Generally, it affects children younger than 5 years old, with the average age when it is found being just 2 years. Most patients have 'high-risk' disease, with spread of the disease to different sites (metastases). This multinational study aims to find out how effective and safe the treatment of a monoclonal anti-GD2 antibody hu14.18K322A (daretabart) is when used together with chemotherapy to treat children and young people who have high-risk neuroblastoma. Conditions: High-Risk Neuroblastoma…