- A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast Cancer — Active Not Recruiting • Phase III • Oncology • NCT05132582.
- Trial testing whether tucatinib improves survival in advanced HER2-positive breast cancer when combined with standard drugs trastuzumab and pertuzumab.
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- Connecting this trial to nearby guidelines, Drug Science and education.
This study is being done to see if tucatinib works better than placebo when given with other drugs to treat participants with HER2-positive breast cancer. A placebo is a pill that looks the same as tucatinib but has no medicine in it. This study will also test what side effects happen when participants take this combination of drugs. A side effect is anything a drug does to the body besides treating your disease. Participants will have cancer that has spread in the body near where it started (locally advanced) and…