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Clinical Trial Active — Not Recruiting Phase III NCT05132582

A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast Cancer

A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast Cancer — Active Not Recruiting • Phase III • Oncology • NCT05132582.

📅 29 Sep 2026 ⏱ 1 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Phase III
NCT ID
NCT05132582
Start
2022-03-07
Completion
2025-09-05
ClinicaliQ Trial Snapshot
  • A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast Cancer — Active Not Recruiting • Phase III • Oncology • NCT05132582.
  • Trial testing whether tucatinib improves survival in advanced HER2-positive breast cancer when combined with standard drugs trastuzumab and pertuzumab.

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What This Trial Is Studying

This study is being done to see if tucatinib works better than placebo when given with other drugs to treat participants with HER2-positive breast cancer. A placebo is a pill that looks the same as tucatinib but has no medicine in it. This study will also test what side effects happen when participants take this combination of drugs. A side effect is anything a drug does to the body besides treating your disease. Participants will have cancer that has spread in the body near where it started (locally advanced) and…

Full Trial Details
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Eligibility criteria, protocol, and results when available
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