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Clinical Trial Active — Not Recruiting Phase III NCT03395197

Talazoparib + Enzalutamide vs. Enzalutamide Monotherapy in mCRPC

Talazoparib + Enzalutamide vs. Enzalutamide Monotherapy in mCRPC — Active Not Recruiting • Phase III • NCT03395197.

📅 29 Sep 2026 ⏱ 1 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Phase III
NCT ID
NCT03395197
Start
2017-12-18
Completion
2022-10-03
ClinicaliQ Trial Snapshot
  • Talazoparib + Enzalutamide vs. Enzalutamide Monotherapy in mCRPC — Active Not Recruiting • Phase III • NCT03395197.
  • Adding talazoparib to enzalutamide delays cancer progression longer than enzalutamide alone in men with advanced prostate cancer.

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What This Trial Is Studying

This study compares rPFS in men with mCRPC treated with talazoparib plus enzalutamide vs. enzalutamide after confirmation of the starting dose of talazoparib in combination with enzalutamide. Conditions: mCRPC Interventions: Talazoparib with enzalutamide, Placebo with enzalutamide Lead Sponsor: Pfizer Planned Enrollment: 1054 participants

Full Trial Details
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Eligibility criteria, protocol, and results when available
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