ClinicaliQ Trial Snapshot
- A Study of Mocertatug Rezetecan in Combination With Anti-cancer Therapies for Advanced Solid Tumors (BEHOLD-2) — Recruiting • Phase I • Oncology • NCT06796907.
- What is being tested: Mocertatug rezetecan, a novel targeted cancer therapy, combined with existing anti-cancer treatments in patients with advanced solid tumors that have become resistant to standard therapies.
- Patient eligibility overview: The trial includes patients with advanced solid tumors (cancers that have spread systemically) who have developed resistance to conventional treatments and have limited remaining therapeutic options.
Use This Page For
- Quick orientation before opening the registry record.
- Checking recruitment status, phase and sponsor at a glance.
- Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying
Advanced solid tumors are cancers that have spread to other parts of the body. While many treatments exist, most people become resistant to them, and the cancer returns. Researchers are developing new treatments that combine different medicines for those who do not respond to single medicine. This study is looking at how safe and tolerable Mocertatug Rezetecan (Mo-Rez) is, how the body handles it, and how well it works when used with other cancer medicines. The study will include participants with advanced solid tumors who have either not responded to…
Eligibility Snapshot
- : * Participants must be 18 years of age inclusive or older, at the time of signing the informed consent, or the legal age of consent in the jurisdiction in which the study is taking place. * Participant capable of giving signed informed consent including compliance with the requirements and restrictions listed in the Informed consent form (ICF) and in this protocol. * Participants with pathologically confirmed advanced solid tumor specific for study Module (key local diagnostic molecular and/or immunophenotyping testing results/tumor cell phenotype results for confirmed diagnosis should be provided) with no more than 4 lines of prior systemic therapies. Please note: 1. Adjuvant +/- neoadjuvant considered one line of therapy 2. Maintenance therapy will be considered as part of the preceding line of therapy (i.e., not counted independently) 3. Unplanned addition or switching to a new drug in a different class is considered a separate line of therapy. If an agent in a regimen is switched to another agent in the same class due to toxicity or intolerance (e.g. hypersensitivity reaction) this is considered part of the same line (i.e. not counted independently). * Requirements for tumor tissue samples: Archival or fresh tumor tissue is required for…
Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.