- First-in-Human Dose-escalation of GSK4425689A: Safety, Tolerability, and PK in Healthy Adults — Recruiting • Phase I • NCT07646353.
- Early-stage trial testing a new antibody drug's safety and how the body processes it in healthy volunteers via injection or infusion.
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This study will assess the safety, tolerability, and pharmacokinetic properties of GSK4425689A monoclonal antibody (mAb) in healthy adults, when administered by either intravenous (IV) or subcutaneous (SC) routes. Conditions: Malaria, Falciparum Interventions: GSK4425689A SC, GSK4425689A IV, Placebo Lead Sponsor: GlaxoSmithKline Planned Enrollment: 40 participants