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Clinical Trial ● Currently Recruiting Phase I NCT07646353

First-in-Human Dose-escalation of GSK4425689A: Safety, Tolerability, and PK in Healthy Adults

First-in-Human Dose-escalation of GSK4425689A: Safety, Tolerability, and PK in Healthy Adults — Recruiting • Phase I • NCT07646353.

📅 05 Oct 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Phase I
NCT ID
NCT07646353
Start
2026-07-27
Completion
2028-04-10
ClinicaliQ Trial Snapshot
  • First-in-Human Dose-escalation of GSK4425689A: Safety, Tolerability, and PK in Healthy Adults — Recruiting • Phase I • NCT07646353.
  • Early-stage trial testing a new antibody drug's safety and how the body processes it in healthy volunteers via injection or infusion.

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  • Quick orientation before opening the registry record.
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What This Trial Is Studying

This study will assess the safety, tolerability, and pharmacokinetic properties of GSK4425689A monoclonal antibody (mAb) in healthy adults, when administered by either intravenous (IV) or subcutaneous (SC) routes. Conditions: Malaria, Falciparum Interventions: GSK4425689A SC, GSK4425689A IV, Placebo Lead Sponsor: GlaxoSmithKline Planned Enrollment: 40 participants

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
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