ClinicaliQ Trial Snapshot
- A Study to Evaluate Sacituzumab Tirumotecan (MK-2870) in Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-2870-015) — Active Not Recruiting • Phase III • Oncology • NCT06356311.
- A new cancer drug (sacituzumab tirumotecan) is being tested against standard treatment in advanced stomach cancer to see if it improves survival.
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What This Trial Is Studying
This study will compare how safe and effective sacituzumab tirumotecan is versus the treatment of physician's choice (TPC) in participants with advanced/metastatic gastroesophageal adenocarcinoma. The primary hypothesis of this study is sacituzumab tirumotecan is superior to TPC with respect to Overall Survival (OS). Conditions: Gastroesophageal Cancer Interventions: Sacituzumab tirumotecan, Trifluridine-Tipiracil, Irinotecan, Paclitaxel, Docetaxel, Rescue medications, Supportive care measures Lead Sponsor: Merck Sharp & Dohme LLC Planned Enrollment: 473 participants