- A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Complement Inhibitors — Active Not Recruiting • Phase III • NCT04432584.
- Crovalimab was as safe and effective as eculizumab in treating PNH patients already on complement inhibitor therapy.
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A study designed to evaluate the safety of crovalimab with eculizumab in participants with PNH currently treated with complement inhibitors. This study will enroll approximately 190 participants. Conditions: Paroxysmal Nocturnal Hemoglobinuria Interventions: Crovalimab, Eculizumab Lead Sponsor: Hoffmann-La Roche Planned Enrollment: 190 participants