- Arterial Stiffness and Endothelial Function in Heart Failure — Recruiting • Cardiology / Cardiovascular • NCT07713719.
- What is being tested: The study investigates how arterial stiffness and endothelial dysfunction contribute to poor outcomes in heart failure patients, aiming to identify vascular mechanisms that may explain persistent clinical deterioration despite current treatments.
- Patient eligibility overview: The trial recruits heart failure patients across the disease spectrum; specific eligibility criteria determine which patients can participate, allowing researchers to assess vascular function in this heterogeneous population.
- Quick orientation before opening the registry record.
- Checking recruitment status, phase and sponsor at a glance.
- Connecting this trial to nearby guidelines, Drug Science and education.
Heart Failure (HF) is a global condition affecting at least 26 million people worldwide. Despite advances in treatment, HF patients continue to experience poor health outcomes. This study aims to improve understanding of the role of blood vessels in people with heart failure. The study will assess how arterial stiffness (how stiff blood vessels are) and endothelial function (how well the lining of blood vessels functions) change over time and respond to treatments received as part of routine clinical care. Blood vessel function and heart performance will be assessed at…
- : * Male and female ≥ 18 years old. * Have a confirmed de-novo diagnosis of Heart failure with preserved ejection fraction or Heart failure with reserved ejection fraction. Common HF phenotypes (e.g., hypertension, diabetes, obesity) will be recorded as part of routine baseline data but will not influence recruitment or sampling. . * Have stable Heart failure in the opinion of the investigator. * Have ability, in the opinion of the investigator, to participate in study activities. * Able to provide written informed consent.
Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.