- A Phase 1/2a Study of WVE-007 in Adults Living With Overweight or Obesity — Recruiting • Phase I / Phase II • Diabetes / Metabolic • NCT06842186.
- WVE-007 is a new injectable weight-loss drug being tested for safety and effectiveness in overweight and obese adults, with and without type 2 diabetes.
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The purpose of this study is to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of ascending doses of WVE-007 when administered subcutaneously (SC) . Part A is a single ascending dose study in adults living with overweight and obesity. The Part B of the study is a repeat dose administration in adult with obesity, with or without Type 2 Diabetes (T2D and non-T2D, respectively). In addition, Part B includes two dose groups that will receive WVE-007 and tirzepatide in adults living with obesity and T2D. Conditions: Overweight and Obesity Interventions:…