- The Use of Advanced Imaging in HFpEF — Recruiting • Cardiology / Cardiovascular • NCT06905405.
- Heart failure with preserved ejection fraction (HFpEF) causes symptoms of breathlessness and leg swelling. It is associated with significant number of hospital admissions and could lead to the patient's death. In HFpEF, the pumping function of the heart is normal but the….
- Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust.
Verify eligibility, endpoints and current status on the original source registry before acting on this summary.
- Quick orientation before opening the registry record.
- Checking recruitment status, phase and sponsor at a glance.
- Connecting this trial to nearby guidelines, Drug Science and education.
Heart failure with preserved ejection fraction (HFpEF) causes symptoms of breathlessness and leg swelling. It is associated with significant number of hospital admissions and could lead to the patient's death. In HFpEF, the pumping function of the heart is normal but the heart is too stiff to fill properly. The first line investigation is an ultrasound of the heart (echocardiography). A number of parameters are assessed that indicate stiffness within the heart or raised pressures within the heart. However, most of these parameters lack sensitivity which can make HFpEF difficult…
- : * Male or female > 18yrs of age. * Symptoms of dysponea on exertion. * NTproBNP >400 ng/L in sinus rhythm (SR). * Baseline TTE demonstrating a dilated LA (LA>34 ml/m2), but that otherwise does not meet the current criteria for the diagnosis of HFpEF or HFrEF (preserved LV systolic function, Normal E/e', no evidence of LVH, Estimated PAP < 35mmhg).
Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.